Affiliations 

  • 1 Department of Dermatology, Hospital Sultanah Aminah, and Clinical School Johor Bahru, Monash University Malaysia, Subang Jaya, Malaysia
  • 2 University of Alabama School of Medicine, Birmingham, Alabama, USA
  • 3 Nihon University School of Medicine, Tokyo, Japan
  • 4 Second Hospital Affiliated to Xi'an Jiaotong University, Xi'an, China
  • 5 Department of Dermatology, Radboud University, Nijmegen, The Netherlands
  • 6 IFPA (International Federation of Psoriasis Associations), Stockholm, Sweden
  • 7 Dermatology Department, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain
  • 8 Department of Dermatology, University of São Paulo, São Paulo, Brazil
  • 9 Department of Dermatology ASST-Spedali Civili Hospital, University of Brescia, Brescia, Italy
Exp Dermatol, 2023 Aug;32(8):1284-1295.
PMID: 36999936 DOI: 10.1111/exd.14794

Abstract

A key principle of clinical studies and case reports is that they should reflect the demographics and epidemiology of the patient population concerned. Here, we have compiled a diverse group of clinical cases of generalized pustular psoriasis (GPP) to showcase the differences in GPP presentation in patients worldwide. We attempt to capture the broad spectrum of clinical presentations of GPP and showcase the diversity of the patient population. The patients included in this series are diverse in age, genetic background, skin phototype and medical history. Moreover, they present with a variety of clinical courses of GPP and different degrees of systemic involvement, and experience flares triggered by different inciting factors. The key learnings from this case series may support physicians in identifying and managing patients with this rare and multifaceted disease that can affect patients both physically and psychologically.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.