Affiliations 

  • 1 Department of Otorhinolaryngology, Hospital Shah Alam Selangor, Shah Alam, MYS
  • 2 Department of Otorhinolaryngology, University Kebangsaan Malaysia Medical Center, Kuala Lumpur, MYS
Cureus, 2023 Sep;15(9):e45710.
PMID: 37868511 DOI: 10.7759/cureus.45710

Abstract

Actinomycosis is a progressive granulomatous infection caused by the bacteria Actinomyces israelii. Classically, the three most common clinical forms are cervicofacial, thoracic, and abdominopelvic. On the contrary, nasopharyngeal actinomycosis is considered to be a rare clinical disease, and its occurrence is extremely low. The infection can take place without any preceding infection or on immunocompromised status. A 25-year-old male with no previous medical history presented with persistent nasal congestion and rhinorrhea. A nasal endoscopy examination revealed an unclearly demarcated nasopharyngeal mass, and a complete microbiology and pathology analysis showed actinomycetes colonies. After two weeks of oral Augmentin therapy, the patient's illness was completely eradicated. Diagnosis of nasopharyngeal actinomycosis is exceptionally crucial, and with early treatment of appropriate antibiotic therapy, the prognosis is excellent. Careful follow-up after adequate treatment as the possibility of frequent relapse is common.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.