Mechanical ventilation practices in Asian intensive care units: A multicenter cross-sectional study

Nam KH 1 , Phua J 2 , Du B 3 , Ohshimo S 4 , Kim HJ 5 , Lim CM 6 Show all authors , Myatra SN 7 , Adib NABN 8 , Arabi YM 9 , Chan MC 10 , Faruq MO 11 , Redjeki IS 12 , Son DN 13 , Nafees KMK 14 , Priyankara D 15 , Patjanasoontorn B 16 , Palo JE 17 , Konkayev A 18 , Shrestha GS 19 , Koh Y 20 , IMPROVE Study Investigators, for the Asian Critical Care Clinical Trials Group

Affiliations 

  • 1 Department of Critical Care Medicine, Seongnam Citizens Medical Center, Seongnam, South Korea
  • 2 FAST and Chronic Programmes, Alexandra Hospital, National University Health System, Singapore; Division of Respiratory and Critical Care Medicine, Department of Medicine, National University Hospital, National University Health System, Singapore
  • 3 State Key Laboratory of Complex, Severe, and Rare Diseases, Medical ICU, Peking Union Medical College Hospital, Beijing, China
  • 4 Department of Emergency and Critical Care Medicine, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan
  • 5 Department of Clinical Epidemiology and Biostatistics, ASAN Medical Center, University of Ulsan College of Medicine, Seoul, South Korea
  • 6 Department of Pulmonary and Critical Care Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea
  • 7 Department of Anaesthesiology, Critical Care and Pain, Tata Memorial Hospital, Homi Bhabha National Institute, Mumbai, India
  • 8 Hospital Sultanah Nur Zahirah, Kuala Terengganu, Malaysia
  • 9 King Saud Bin Abdulaziz University for Health Sciences, King Abdullah International Medical Research Center, Ministry of National Guard Health Affairs, Riyadh, Saudi Arabia
  • 10 Division of Critical Care and Respiratory Therapy, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan; National Chung Hsing University, Taichung, Taiwan
  • 11 Critical Care Medicine and Emergency Medicine, United Medical College and United Hospital, Dhaka 1212, Bangladesh
  • 12 Faculty of Medicine, Department of Anesthesiology and Intensive Care, Padjadjaran University, Dr. Hasan Sadikin National Referral Hospital Bandung, Bandung, Indonesia
  • 13 Center for Critical Care Medicine, Bach Mai Hospital, University of Medicine and Pharmacy, Hanoi National University, Viet Nam
  • 14 RIPAS Hospital, Bandar Seri Begawan, Brunei Darussalam
  • 15 Critical Care Medicine, National Hospital of Sri Lanka, Sri Lanka
  • 16 Division of Respiratory and Critical Care Medicine, Department of Internal Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand
  • 17 Acute and Critical Care Institute, The Medical City, Pasig City, Philippines
  • 18 Anaesthesia and ICU Department, Astana Medical University, Institution of Traumatology and Orthopedics, Nur-Sultan, Kazakhstan
  • 19 Department of Critical Care Medicine Institute of Medicine, Tribhuvan University Teaching Hospital, Kathmandu, Nepal
  • 20 Department of Pulmonary and Critical Care Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea. Electronic address: yskoh@amc.seoul.kr
J Crit Care, 2024 Feb;79:154452.
PMID: 37948944 DOI: 10.1016/j.jcrc.2023.154452

Abstract

PURPOSE: This study investigated current practices of mechanical ventilation in Asian intensive care units, focusing on tidal volume, plateau pressure, and positive end-expiratory pressure (PEEP).

MATERIALS AND METHODS: In this multicenter cross-sectional study, data on mechanical ventilation and clinical outcomes were collected. Predictors of mortality were analyzed by univariate and multivariable logistic regression. A scoring system was generated to predict 28-day mortality.

RESULTS: A total of 1408 patients were enrolled. In 138 patients with acute respiratory distress syndrome (ARDS), 65.9% were on a tidal volume ≤ 8 ml/kg predicted body weight (PBW), and 71.3% were on sufficient PEEP. In 1270 patients without ARDS, 88.8% were on a tidal volume ≤ 10 ml/kg PBW. A plateau pressure 

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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