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Kt/V: achievement, predictors and relationship to mortality in hemodialysis patients in the Gulf Cooperation Council countries: results from DOPPS (2012-18)

AlSahow A 1 , Muenz D 2 , Al-Ghonaim MA 3 , Al Salmi I 4 , Hassan M 5 , Al Aradi AH 6 Show all authors , Hamad A 7 , Al-Ghamdi SMG 8 , Shaheen FAM 9 , Alyousef A 10 , Bieber B 2 , Robinson BM 2 , Pisoni RL 2

Affiliations 

  • 1 Nephrology Division, Jahra Hospital, Jahra, Kuwait
  • 2 Arbor Research Collaborative for Health, Ann Arbor, MI, USA
  • 3 Medicine Department, Saudi Center for Organ Transplantation, King Saud University, Riyadh, KSA
  • 4 Renal Medicine Department, Royal Hospital, Muscat, Oman
  • 5 Nephrology Division, Shaikh Khalifa Medical Center, Abu Dhabi, UAE
  • 6 Nephrology Division, Salmaniya Medical Complex, Manama, Bahrain
  • 7 Nephrology Department, Hamad Hospital, Doha, Qatar
  • 8 Medicine Department, Faculty of Medicine, King Abdulaziz University, Jeddah, KSA
  • 9 Nephrology Division, Solyman Fakeeh Hospital, Jeddah, KSA
  • 10 Nephrology Division, Farwaniya Hospital, Sabah AlNasser, Kuwait
Clin Kidney J, 2021 Mar;14(3):820-830.
PMID: 33777365 DOI: 10.1093/ckj/sfz195

Abstract

BACKGROUND: Dialysis adequacy, as measured by single pool Kt/V, is an important parameter for assessing hemodialysis (HD) patients' health. Guidelines have recommended Kt/V of 1.2 as the minimum dose for thrice-weekly HD. We describe Kt/V achievement, its predictors and its relationship with mortality in the Gulf Cooperation Council (GCC) (Bahrain, Kuwait, Oman, Qatar, Saudi Arabia and the United Arab Emirates).

METHODS: We analyzed data (2012-18) from the prospective cohort Dialysis Outcomes and Practice Patterns Study for 1544 GCC patients ≥18 years old and on dialysis >180 days.

RESULTS: Thirty-four percent of GCC HD patients had low Kt/V (<1.2) versus 5%-17% in Canada, Europe, Japan and the USA. Across the GCC countries, low Kt/V prevalence ranged from 10% to 54%. In multivariable logistic regression, low Kt/V was more common (P 

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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