Affiliations 

  • 1 Department of Chemistry, Christ University, Bangalore 560029, Karnataka, India
  • 2 Department of Food Science and Biotechnology, College of Life Sciences, Sejong University, Seoul, South Korea
  • 3 Department of Life Sciences, Christ University, Bangalore 560029, Karnataka, India
  • 4 Department of Botany, Sri Vidya Mandir Arts and Science College (Autonomous), Krishnagiri 636 902, Tamil Nadu, India
  • 5 Universidad UTE, Centro de Investigación en Salud Públicay Epidemiología Clínica (CISPEC), Quito 170527, Ecuador; Department of Biomaterials, Saveetha Dental College and Hospital, Saveetha Institute of Medical and Technical Sciences, Chennai 600077, India. Electronic address: khesam2@live.utm.my
  • 6 Department of Smart Engineering and Advanced Technology, Faculty of Artificial Intelligence, Universiti Teknologi Malaysia, Jalan Sultan Yahya Petra, 54100 Kuala Lumpur, Malaysia. Electronic address: shreeshivadasan.kl@utm.my
  • 7 Department of Life Sciences, Christ University, Bangalore 560029, Karnataka, India. Electronic address: vasantha.vl@christuniversity.in
Int J Pharm, 2025 Feb 10;670:125105.
PMID: 39722373 DOI: 10.1016/j.ijpharm.2024.125105

Abstract

The biosynthesis of nanomaterials is a vast and expanding field of study due to their applications in a variety of fields, particularly the pharmaceutical and biomedical fields. Various synthetic routes, including physical and chemical methods, have been developed in order to generate metal nanoparticles (NPs) with definite shapes and sizes. In this review, focused on the recent advancements in the green synthetic methods for the generation of silver, zinc and copper NPs with simple and eco-friendly approaches and the potential of the biosynthesized metal and metal oxide NPs as alternative and therapeutic agent for the treatment of inflammatory diseases. Inflammation is a body's own defense mechanism that can become chronic inflammation affecting healthy cells. Owning to the size-based advantages of NPs which can mitigate in theses medical conditions and serve as anti-inflammatory drugs. The factors influencing their physicochemical properties, toxicity, biocompatibility and mode of action to formulate an effective nanomedicine in the treatment of inflammation.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.