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Release behavior and toxicity profiles towards A549 cell lines of ciprofloxacin from its layered zinc hydroxide intercalation compound

Abdul Latip AF 1 , Hussein MZ 1 , Stanslas J 2 , Wong CC 2 , Adnan R 3

Affiliations 

  • 1 Materials Synthesis and Characterization Laboratory (MSCL), Institute of Advanced Technology (ITMA), Universiti Putra Malaysia UPM, 43400 Serdang, Selangor, Malaysia
  • 2 Pharmacotherapeutics Unit, Department of Medicine, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia UPM, 43400 Serdang, Selangor, Malaysia
  • 3 School of Chemical Sciences, Universiti Sains Malaysia, 11800 Pulau, Pinang, Malaysia
Chem Cent J, 2013;7:119.
PMID: 23849189 DOI: 10.1186/1752-153X-7-119

Abstract

Layered hydroxides salts (LHS), a layered inorganic compound is gaining attention in a wide range of applications, particularly due to its unique anion exchange properties. In this work, layered zinc hydroxide nitrate (LZH), a family member of LHS was intercalated with anionic ciprofloxacin (CFX), a broad spectrum antibiotic via ion exchange in a mixture solution of water:ethanol.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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