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Genome sequencing and annotation of multidrug resistant Mycobacterium tuberculosis (MDR-TB) PR10 strain

Halim MZ 1 , Jaafar MM 1 , Teh LK 2 , Ismail MI 1 , Lee LS 1 , Ngeow YF 3 Show all authors , Nor NM 4 , Zainuddin ZF 5 , Tang TH 6 , Najimudin MN 7 , Salleh MZ 2

Affiliations 

  • 1 Integrative Pharmacogenomics Institute (iPROMISE), Universiti Teknologi MARA (UiTM), Malaysia
  • 2 Integrative Pharmacogenomics Institute (iPROMISE), Universiti Teknologi MARA (UiTM), Malaysia; Faculty of Pharmacy, Universiti Teknologi MARA (UiTM), Selangor, Malaysia
  • 3 Faculty of Medicine & Health Sciences, Universiti Tunku Abdul Rahman, Malaysia
  • 4 School of Health Sciences, Health Campus, Universiti Sains Malaysia, Malaysia; Institute for Research in Molecular Medicine (INFORMM), Universiti Sains Malaysia, Malaysia
  • 5 School of Health Sciences, Health Campus, Universiti Sains Malaysia, Malaysia; Business and Technopreneur Development Division, Malaysian Technology Development Corporation (MTDC) Sdn. Bhd, Malaysia
  • 6 Advanced Medical and Dental Institute (AMDI), Universiti Sains Malaysia, Malaysia
  • 7 School of Biological Sciences, Universiti Sains Malaysia, Malaysia
Genom Data, 2016 Mar;7:245-6.
PMID: 26981419 DOI: 10.1016/j.gdata.2016.01.002

Abstract

Here, we report the draft genome sequence and annotation of a multidrug resistant Mycobacterium tuberculosis strain PR10 (MDR-TB PR10) isolated from a patient diagnosed with tuberculosis. The size of the draft genome MDR-TB PR10 is 4.34 Mbp with 65.6% of G + C content and consists of 4637 predicted genes. The determinants were categorized by RAST into 400 subsystems with 4286 coding sequences and 50 RNAs. The whole genome shotgun project has been deposited at DDBJ/EMBL/GenBank under the accession number CP010968.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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