Affiliations 

  • 1 a Centre for Drug Delivery Research, Faculty of Pharmacy , Universiti Kebangsaan Malaysia , Kuala Lumpur , Malaysia
  • 2 b Institute of Systems Biology (INBIOSIS) , Universiti Kebangsaan Malaysia , Bangi , Selangor , Malaysia
  • 3 d Faculty of Pharmacy , Universiti Kebangsaan Malaysia , Kuala Lumpur , Malaysia
Expert Opin Drug Deliv, 2016 May;13(5):621-32.
PMID: 26943455 DOI: 10.1517/17425247.2016.1160889

Abstract

Oral insulin administration suffers gastrointestinal tract (GIT) degradation and inadequate absorption from the intestinal epithelium resulting in poor bioavailability. This study entails in vitro and in vivo assessment of stimuli-responsive hydrogel microparticles (MPs) in an attempt to circumvent GI barrier and enhance oral insulin bioavailability.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.