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Effectiveness of blood flow restricted exercise compared with standard exercise in patients with recurrent low back pain: study protocol for a randomized controlled trial

Amano S 1 , Ludin AF 2 , Clift R 3 , Nakazawa M 4 , Law TD 5 , Rush LJ 6 Show all authors , Manini TM 7 , Thomas JS 8 , Russ DW 9 , Clark BC 10

Affiliations 

  • 1 Ohio Musculoskeletal and Neurological Institute (OMNI), Ohio University, 250 Irvine Hall, 1 Ohio University, Athens, OH, 43147, USA. amano@ohio.edu
  • 2 Ohio Musculoskeletal and Neurological Institute (OMNI), Ohio University, 250 Irvine Hall, 1 Ohio University, Athens, OH, 43147, USA
  • 3 Clinical and Translational Research Unit (CTRU), Ohio University, Athens, OH, 45701, USA. cliftr@ohio.edu
  • 4 Ohio Musculoskeletal and Neurological Institute (OMNI), Ohio University, 250 Irvine Hall, 1 Ohio University, Athens, OH, 43147, USA. nakazawa@ohio.edu
  • 5 Ohio Musculoskeletal and Neurological Institute (OMNI), Ohio University, 250 Irvine Hall, 1 Ohio University, Athens, OH, 43147, USA. lawt@ohio.edu
  • 6 Clinical and Translational Research Unit (CTRU), Ohio University, Athens, OH, 45701, USA. rush@ohio.edu
  • 7 Department of Geriatric Medicine, University of Florida, 2004 Mowry Road, PO Box 100107, Gainesville, FL, 32611, USA. tmanini@ufl.edu
  • 8 Ohio Musculoskeletal and Neurological Institute (OMNI), Ohio University, 250 Irvine Hall, 1 Ohio University, Athens, OH, 43147, USA. thomasj5@ohio.edu
  • 9 Ohio Musculoskeletal and Neurological Institute (OMNI), Ohio University, 250 Irvine Hall, 1 Ohio University, Athens, OH, 43147, USA. russd@ohio.edu
  • 10 Ohio Musculoskeletal and Neurological Institute (OMNI), Ohio University, 250 Irvine Hall, 1 Ohio University, Athens, OH, 43147, USA. clarkb2@ohio.edu
Trials, 2016;17:81.
PMID: 26867541 DOI: 10.1186/s13063-016-1214-7

Abstract

Low back pain is a highly prevalent condition in the United States and has a staggeringly negative impact on society in terms of expenses and disability. It has previously been suggested that rehabilitation strategies for persons with recurrent low back pain should be directed to the medial back muscles as these muscles provide functional support of the lumbar region. However, many individuals with low back pain cannot safely and effectively induce trunk muscle adaptation using traditional high-load resistance exercise, and no viable low-load protocols to induce trunk extensor muscle adaptation exist. Herein, we present the study protocol for a randomized controlled trial that will investigate the "cross-transfer" of effects of a novel exercise modality, blood flow restricted exercise, on cross-sectional area (primary outcome), strength and endurance (secondary outcomes) of trunk extensor muscles, as well as the pain, disability, and rate of recurrence of low back pain (tertiary outcomes).

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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