Affiliations 

  • 1 a Laboratory of Natural Products Chemistry , Institute for Tropical Biology and Conservation, Universiti Malaysia Sabah , Kota Kinabalu 88400 , Malaysia
  • 2 b Institute for Tropical Biology and Conservation, Universiti Malaysia Sabah , Kota Kinabalu 88400 , Malaysia
J Asian Nat Prod Res, 2016 Jul;18(7):690-6.
PMID: 26828126 DOI: 10.1080/10286020.2015.1134503

Abstract

A new compound, chandonanol (1), along with four known compounds, chandonanthone (2), iso-chandonanthone (3), anastreptene (4), and (6R,7S)-sesquiphellandrene (5), was isolated from the MeOH extract of Bornean liverwort Chandonanthus hirtellus. The structure of the new metabolite was established by analyses of the spectroscopic data (1D NMR, 2D NMR, HRESIMS, and IR). These compounds were tested for their activity against antibiotic-resistant clinical strains. Chandonanol (1) exhibited potent bactericidal activity against Staphylococcus aureus and Escherichia coli.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.