• 1 a Laboratory of Natural Products Chemistry, Institute for Tropical Biology and Conservation , Universiti Malaysia Sabah , Kota Kinabalu 88400 , Malaysia
J Asian Nat Prod Res, 2019 Mar;21(3):241-247.
PMID: 29281900 DOI: 10.1080/10286020.2017.1417265


Two new halogenated nonterpenoids C15-acetogenins, nangallenes A-B (1-2), together with two known halogenated compounds itomanallene A (3) and 2,10-dibromo-3-chloro-α-chamigrene (4), were isolated and identified from the organic extract of the marine red alga Laurencia nangii Masuda collected from the coastal waters in Semporna, Borneo. Their structures were established by means of spectroscopic analysis including IR, high-resolution electrospray ionization mass spectrometry (HRESI-MS), and 1D and 2D NMR techniques. All these metabolites were submitted for the antifungal assay against four species of selected marine fungi. Compounds 1-4 showed potent activity against Haliphthoros sabahensis and Lagenidium thermophilum.

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