Collagen Triple Helix Repeat Containing-1 (CTHRC1) Expression in Oral Squamous Cell Carcinoma (OSCC): Prognostic Value and Clinico-Pathological Implications

Lee CE; Vincent-Chong VK; Ramanathan A; Kallarakkal TG; Karen-Ng LP; Ghani WM; Rahman ZA; Ismail SM; Abraham MT; Tay KK; Mustafa WM; Cheong SC; Zain RB

doi:10.7150/ijms.11605

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Collagen Triple Helix Repeat Containing-1 (CTHRC1) Expression in Oral Squamous Cell Carcinoma (OSCC): Prognostic Value and Clinico-Pathological Implications

Lee CE , Vincent-Chong VK , Ramanathan A , Kallarakkal TG , Karen-Ng LP , Ghani WM Show all authors , Rahman ZA , Ismail SM , Abraham MT , Tay KK , Mustafa WM , Cheong SC ¹ , Zain RB

Affiliations

¹ 2. Department of Oro-Maxillofacial Surgical and Medical Sciences, Faculty of Dentistry, University of Malaya, Kuala Lumpur, Malaysia; ; 6. Oral Cancer Research Team, Cancer Research Initiatives Foundation (CARIF), Selangor Darul Ehsan, Malaysia

Int J Med Sci, 2015;12(12):937-45.

PMID: 26664254 DOI: 10.7150/ijms.11605

Abstract

Collagen Triple Helix Repeat Containing 1 (CTHRC1) is a protein often found to be over-expressed in various types of human cancers. However, correlation between CTHRC1 expression level with clinico-pathological characteristics and prognosis in oral cancer remains unclear. Therefore, this study aimed to determine mRNA and protein expression of CTHRC1 in oral squamous cell carcinoma (OSCC) and to evaluate the clinical and prognostic impact of CTHRC1 in OSCC.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.