The aim of the present study was to assess the anti-obesity and lipolysis effects of Strobilanthes
crispus leaves extract (SCE) in diet-induced obese (DIO) rats by administering 1% (w/w) of
SCE in drinking water. Methods: Normal Sprague-Dawley rats were induced obese using a
high-fat (HF) diet formulation for 14 weeks. DIO rats were subsequently treated with 1% (w/w)
SCE while the HF diet was switched to normal rat chow diet. Food intake, water intake and
bodyweight were measured weekly. Other parameters e.g. blood lipid profile were determined
in normal and DIO rats before and after treatment with SCE. Histopathological changes in the
liver were also observed after treatment. Results: Prior to treatment, DIO rats have significantly
higher (p