ISH ADA-04 TRANSCRIPTOME PATHWAY ANALYSIS OF AUTONOMOUS AND PHYSIOLOGICAL ALDOSTERONE-PRODUCING HUMAN TISSUE

Zhou J; Lam B; Neogi S; Yeo G; Azizan E; Brown M

ISH ADA-04 TRANSCRIPTOME PATHWAY ANALYSIS OF AUTONOMOUS AND PHYSIOLOGICAL ALDOSTERONE-PRODUCING HUMAN TISSUE

Zhou J ¹ , Lam B , Neogi S , Yeo G , Azizan E , Brown M

Affiliations

¹ aDepartment of Clinical Pharmacology Unit, Department of Medicine, University of Cambridge, United Kingdom bDepartment of Wellcome Trust-MRC Institute of Metabolic Science, Box 289, Addenbrooke's Hospital, Cambridge, MRC Metabolic Diseases Unit, University of Cambridge Metabolic Research Laboratories, United Kingdom cDepartment of Clinical Biochemistry, Genomics CoreLab, Cambridge National Institute for Health Research (NIHR) Biomedical Research Centre (BRC), United Kingdom dDepartment of medicine, Faculty of Medicine, The National University of Malaysia (UKM) Medical Centre, Kuala Lumpur, Malaysia

J Hypertens, 2016 Sep;34 Suppl 1 - ISH 2016 Abstract Book:e40.

PMID: 27753883

Abstract

Primary aldosteronism (PA) is the most common type of secondary hypertension occurring in ∼10% of hypertensive patients. Up to 50% of PA is caused by aldosterone-producing adenomas (APA). This study is to identify the potential biological processes and canonical pathways involved with aldosterone regulation, APA formation, or APA and ZG cell functions.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.