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A Commensal Protozoan Strikes a Balance in the Gut

Loke P 1 , Lim YAL 2

Affiliations 

  • 1 Department of Microbiology, New York University School of Medicine, New York, NY 10016, USA. Electronic address: png.loke@nyumc.org
  • 2 Department of Parasitology, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia. Electronic address: limailian@um.edu.my
Cell Host Microbe, 2016 10 12;20(4):417-419.
PMID: 27736641 DOI: 10.1016/j.chom.2016.09.016

Abstract

Gut commensals profoundly affect host immunity and intestinal homeostasis, but the impact of commensal eukaryotic protozoans is poorly understood. In a recent Cell paper, Chudnovskiy et al. (2016) identify a commensal protozoan, Tritrichomonas musculis, that can enhance anti-bacterial defenses, but at the cost of increasing intestinal inflammation.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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