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Photodynamic therapy for polypoidal choroidal vasculopathy secondary to choroidal nevus

Wong JG 1 , Lai XJ 2 , Sarafian RY 3 , Wong HS 4 , Smith JB 5

Affiliations 

  • 1 Strathfield Retina Clinic, Sydney, NSW, Australia; Medical Retina Unit, Sydney Eye Hospital, Sydney, NSW, Australia; Save Sight Institute, University of Sydney, Sydney, NSW, Australia
  • 2 Strathfield Retina Clinic, Sydney, NSW, Australia
  • 3 School of Medicine, University of Queensland, Brisbane, QLD, Australia
  • 4 Department of Ophthalmology, Universiti Kebangsaan Malaysia Medical Centre, Kuala Lumpur, Malaysia
  • 5 Ophthalmology Clinic, Children's Hospital Westmead, Sydney, NSW, Australia
Int Med Case Rep J, 2017;10:51-54.
PMID: 28243154 DOI: 10.2147/IMCRJ.S107648

Abstract

We report a case of a Caucasian female who developed active polypoidal choroidal vasculopathy (PCV) at the edge of a stable choroidal nevus and was successfully treated with verteporfin photodynamic therapy. No active polyp was detectable on indocyanine green angiography 2 years after treatment, and good vision was maintained. Indocyanine green angiography is a useful investigation to diagnose PCV and may be underutilized. Unlike treatment of choroidal neovascularization secondary to choroidal nevus, management of PCV secondary to nevus may not require intravitreal anti-vascular endothelial growth factor therapy. Photodynamic monotherapy may be an effective treatment of secondary PCV.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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