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Unilateral rhino-orbital-cerebral mucormycosis with contralateral endogenous fungal endophthalmitis

Ho HC 1 , Liew OH 2 , Teh SS 2 , Hanizasurana H 2 , Ibrahim M 3 , Shatriah I 3

Affiliations 

  • 1 Department of Ophthalmology, School of Medical Sciences, Universiti Sains Malaysia, Kelantan, Malaysia ; Department of Ophthalmology, Hospital Selayang, Lebuhraya Selayang-Kepong, Selangor Darul Ehsan, Malaysia
  • 2 Department of Ophthalmology, Hospital Selayang, Lebuhraya Selayang-Kepong, Selangor Darul Ehsan, Malaysia
  • 3 Department of Ophthalmology, School of Medical Sciences, Universiti Sains Malaysia, Kelantan, Malaysia
Clin Ophthalmol, 2015;9:553-6.
PMID: 25848206 DOI: 10.2147/OPTH.S82204

Abstract

Rhino-orbital-cerebral mucormycosis (ROCM) is an uncommon but fatal fungal infection. We report a rare case of unilateral ROCM with ipsilateral central retinal artery occlusion and contralateral choroiditis, which later progressed to endogenous fungal endophthalmitis. The patient was successfully treated with sinuses debridement, systemic liposomal amphotericin B, and intravitreal amphotericin B. The endophthalmitis completely resolved with good vision, but the ROCM eye remained blind due to central retinal artery occlusion.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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