Affiliations 

  • 1 Dept. of ECE, ITER, SOA Deemed to be University, Odisha, India
  • 2 Dept. of Electronics and Computer Engineering, Ngee Ann Polytechnic, Singapore; Dept. of Biomedical Engineering, School of Science and Technology, Singapore University of Social Science, Singapore; School of Medicaine, Faculty of Health and Medical Sciences, Taylor's University, 47500, Subang Jaya, Malaysia. Electronic address: aru@np.edu.sg
  • 3 Dept. of Mathematics, Silicon Institute of Technology, Bhubaneswar, Odisha, India
  • 4 Dept. of Neurology, All India Institute of Medical Sciences, Bhubaneswar, India
  • 5 School of Electronics Engineering, KIIT Deemed to be University, Odisha, India. Electronic address: sukanta.sabatfet@kiit.ac.in
Comput Biol Med, 2018 12 01;103:116-129.
PMID: 30359807 DOI: 10.1016/j.compbiomed.2018.10.016

Abstract

It is difficult to develop an accurate algorithm to detect the stroke lesions using magnetic resonance imaging (MRI) images due to variation in different lesion sizes, variation in morphological structure, and similarity in intensity of lesion with normal brain in three types of stroke, namely partial anterior circulation syndrome (PACS), lacunar syndrome (LACS) and total anterior circulation stroke (TACS). In this paper, we have integrated the advantages of Delaunay triangulation (DT) and fractional order Darwinian particle swarm optimization (FODPSO), called DT-FODPSO technique for automatic segmentation of the structure of the stroke lesion. The approach was validated on 192 MRI images obtained from different stroke subjects. Statistical and morphological features were extracted and classified according to the Oxfordshire community stroke project (OCSP) using support vector machine (SVM) and random forest (RF) classifiers. The method effectively detected the stroke lesions and achieved promising results with an average sensitivity of 0.93, accuracy of 0.95, JI of 0.89 and Dice similarity index of 0.93 using RF classifier. These promising results indicates the DT based optimized approach is efficient in detecting ischemic stroke and it can aid the neuro-radiologists to validate their routine screening.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.