Affiliations 

  • 1 School of Health Sciences, Universiti Sains Malaysia, Health Campus, 16150, Kubang Kerian, Kelantan, Malaysia
  • 2 DNA Databank Division (D13), Criminal Investigation Department, Royal Malaysian Police, 43200, Cheras, Selangor, Malaysia
  • 3 Noguchi Memorial Institute for Medical Research, University of Ghana, Legon, 00233, Accra, Ghana
  • 4 Forensic Science Laboratory, Criminal Investigation Department, Ghana Police Service, 00233, Accra, Ghana
  • 5 School of Biological Sciences, Victoria University of Wellington, P.O. Box 600, Wellington, New Zealand
  • 6 School of Health Sciences, Universiti Sains Malaysia, Health Campus, 16150, Kubang Kerian, Kelantan, Malaysia. edinur@usm.my
Int J Legal Med, 2020 Jul;134(4):1313-1315.
PMID: 31154498 DOI: 10.1007/s00414-019-02099-w

Abstract

In this study, 268 samples for unrelated males belonging to the five major human subpopulation groups in Ghana (Akan, Ewe, Mole-Dagbon, Ga-Dangme and Guang) were genetically characterised for 23 Y chromosome short tandem repeat (STR) loci using the Powerplex® Y23 STR kit. A total of 263 complete haplotypes were recorded of which 258 were unique. The haplotype diversity, discriminating capacity and match probability for the pooled population data were 0.9998, 0.9627 and 0.0039, respectively. The pairwise genetic distance (RST) for the Ghanaian datasets and other reference populations deposited in the Y-STR Haplotype Reference Database (YHRD) were estimated and mapped using multidimensional scaling (MDS) plot. The Guang and Ewe were significantly different from the Akan, Mole-Dagbon and Ga-Dangme. However, the five Ghanaian datasets were all plotted close together with other African populations in the MDS data mapping.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.