Affiliations 

  • 1 Department of Environmental and Occupational Health, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400, UPM, Serdang, Selangor Darul Ehsan, Malaysia
  • 2 Department of Environmental and Occupational Health, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400, UPM, Serdang, Selangor Darul Ehsan, Malaysia. Electronic address: smpraveena@upm.edu.my
  • 3 Department of Environmental Sciences, Faculty of Environmental Studies, Universiti Putra Malaysia, 43400, UPM, Serdang, Selangor Darul Ehsan, Malaysia
Ecotoxicol Environ Saf, 2019 Dec 15;185:109681.
PMID: 31561079 DOI: 10.1016/j.ecoenv.2019.109681

Abstract

Studies on the occurrence of pharmaceutical residues in drinking water were conducted especially in developed countries. However, limited studies reported the occurrence of pharmaceutical residues in developing countries. Thus, this study is conducted to fill the knowledge gap of pharmaceutical residue occurrences in developing countries, particularly in Malaysia, along with public awareness level and its potential human health risk. This study investigates public awareness level of drinking water quality and pharmaceutical handling, the occurrence of nine pharmaceutical residues (amoxicillin, caffeine, chloramphenicol, ciprofloxacin, dexamethasone, diclofenac, nitrofurazone, sulfamethoxazole, and triclosan) and potential human health risks in drinking water from Kajang (Malaysia) using commercially competitive enzyme-linked immunosorbent assay kits. In general, the public awareness level of Kajang population showed poor knowledge (82.02%), and less positive attitude (98.88%) with a good practice score (57.3%). Ciprofloxacin was detected at the highest concentration (0.667 ng/L) while amoxicillin was at the lowest concentration (0.001 ng/L) in drinking water from Kajang (Malaysia). Nevertheless, all the reported occurrences were lower than previous studies conducted elsewhere. There was no appreciable potential human health risk for all the pharmaceutical residues as the risk quotient (RQ) values were less than 1 (RQ 

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.