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Alteration of glucose lowering effect of glibenclamide on single and multiple treatments with fenofibrate in experimental rats and rabbit models

Candasamy M 1 , Murthy TE 2 , Gubiyappa KS 1 , Chellappan DK 1 , Gupta G 1

Affiliations 

  • 1 Department of Life Sciences, School of Pharmacy, International Medical University, Bukit Jalil, Kuala Lumpur, Malaysia
  • 2 Department of Pharmaceutics, Bapatla College of Pharmacy, Bapatla, Andhra Pradesh, India
J Basic Clin Pharm, 2014 Jun;5(3):62-7.
PMID: 25278668 DOI: 10.4103/0976-0105.139728

Abstract

Diabetes mellitus is a syndrome of multiple etiologies. Both type 1 and type 2 diabetes lead to multiple abnormalities of lipid and lipoprotein metabolism. The aim of this investigation was to study the influence of fenofibrate on the blood glucose lowering effect of glibenclamide.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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