Fulltext

Factors Associated with Intention to Donate Hematopoietic Stem Cells among Blood Donors

Ting CY 1 , Lee YF 2 , Lim CJ 3 , Ting RSK 4 , Md Zahrin MM 5 , Ahmad AS 6 Show all authors , Wong JSY 7 , Arip M 8 , Zakaria Z 8 , Ahmad Zaidi Adruce S 9 , Tnay JKS 10 , Wong YS 5

Affiliations 

  • 1 Pharmacy Practice and Development Division, Sarawak State Health Department, Ministry of Health, Kuching, Malaysia
  • 2 Institute of Global Health, Faculty of Medicine, University of Geneva, Geneva, Switzerland
  • 3 Clinical Research and Innovation Office, Tan Tock Seng Hospital, Singapore, Singapore
  • 4 Jeffrey Cheah School of Medicine and Health Sciences, Monash University, Selangor, Malaysia
  • 5 Blood Transfusion Services and Blood Bank Department, Sarawak General Hospital, Ministry of Health, Kuching, Malaysia
  • 6 Blood Transfusion Services and Blood Bank Unit, Sibu Hospital, Ministry of Health, Sibu, Malaysia
  • 7 Hospital Miri, Ministry of Health, Miri, Malaysia
  • 8 Institute for Medical Research, Ministry of Health, Kuala Lumpur, Malaysia
  • 9 Faculty of Cognitive Sciences and Human Development, Universiti Malalysia Sarawak, Kota Samarahan, Malaysia
  • 10 Institute of Borneo Studies, Universiti Malalysia Sarawak, Kota Samarahan, Malaysia
Transfus Med Hemother, 2021 May;48(3):188-195.
PMID: 34177425 DOI: 10.1159/000512197

Abstract

Introduction: Past studies pay little attention to the intention to donate hematopoietic stem cells (HSC) among blood donors. This study investigated the level of and the influence of socio-demographic characteristics, knowledge, attitude, subjective norm and self-efficacy on the intention to donate HSC among blood donors.

Methods: This cross-sectional study recruited blood donors at selected public hospitals in the Malaysian State of Sarawak in 2019. A structured questionnaire was developed based on the review of relevant literature. It gathered information on socio-demographic characteristics, knowledge, attitude, subjective norm and self-efficacy on the intention to donate HSC. Variables with a p value <0.200 in bivariate analysis were included in the variable selection for regression modeling to examine their associations with the intention to donate HSC.

Results: A total of 569 blood donors participated (94.5% response rate). Overall, 87.1% reported a positive intention to donate HSC. In the regression model, the factor with the greatest association with intention to donate HSC was subjective norms about HSC donation (β = 0.35, 95% CI 0.27-0.42), followed by attitude about regulations of HSC donation (β= 0.21, 95% CI 0.13-0.35), self-efficacy on HSC donation (β = 0.15, 95% CI 0.09-0.32), attitude about the potential side effects of HSC donation (β = 0.14, 95% CI 0.02-0.10) and highest education level (β = 0.10, 95% CI 0.03-0.44).

Conclusions: The findings can be used to formulate a better strategy in promoting HSC donation among blood donors in the region.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

Similar publications