Affiliations 

  • 1 School of Computer Science and Engineering, Vellore Institute of Technology, Vellore, India
  • 2 School of Information Technology and Engineering, Vellore Institute of Technology, Vellore, India
  • 3 Center for Cyber Security, Faculty of Information Science and Technology, Universiti Kebangsaan Malaysia (UKM), Bangi, Malaysia
  • 4 Department of Mechanical Engineering, University of South Carolina, Columbia, SC, United States
  • 5 Computer Science Department, College of Science and Humanities, Imam Abdulrahman Bin Faisal University, Jubail, Saudi Arabia
  • 6 Computer Science Department, College of Computer Engineering and Science, Prince Sattam Bin Abdulaziz University, Al-Kharj, Saudi Arabia
  • 7 Department of Mathematics, College of Science and Humanity, Prince Sattam Bin Abdulaziz University, Al-Kharj, Saudi Arabia
Front Public Health, 2021;9:751536.
PMID: 34708019 DOI: 10.3389/fpubh.2021.751536

Abstract

Alzheimer's Disease (AD) is a neurodegenerative irreversible brain disorder that gradually wipes out the memory, thinking skills and eventually the ability to carry out day-to-day tasks. The amount of AD patients is rapidly increasing due to several lifestyle changes that affect biological functions. Detection of AD at its early stages helps in the treatment of patients. In this paper, a predictive and preventive model that uses biomarkers such as the amyloid-beta protein is proposed to detect, predict, and prevent AD onset. A Convolution Neural Network (CNN) based model is developed to predict AD at its early stages. The results obtained proved that the proposed model outperforms the traditional Machine Learning (ML) algorithms such as Logistic Regression, Support Vector Machine, Decision Tree Classifier, and K Nearest Neighbor algorithms.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.