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Cosmetic Applications of Bee Venom

El-Wahed AAA 1 , Khalifa SAM 2 , Elashal MH 3 , Musharraf SG 4 , Saeed A 5 , Khatib A 6 Show all authors , Tahir HE 7 , Zou X 7 , Naggar YA 8 , Mehmood A 9 , Wang K 10 , El-Seedi HR 3

Affiliations 

  • 1 Department of Bee Research, Plant Protection Research Institute, Agricultural Research Centre, Giza 12627, Egypt
  • 2 Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, S-106 91 Stockholm, Sweden
  • 3 Department of Chemistry, Faculty of Science, Menoufia University, Shebin El-Kom 32512, Egypt
  • 4 H.E.J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi 75270, Pakistan
  • 5 Department of Chemistry, Quaid-i-Azam University, Islamabad 45320, Pakistan
  • 6 Pharmacognosy Research Group, Department of Pharmaceutical Chemistry, Kulliyyah of Pharmacy, International Islamic University Malaysia, Kuantan 25200, Pahang Darul Makmur, Malaysia
  • 7 School of Food and Biological Engineering, Jiangsu University, Zhenjiang 212013, China
  • 8 General Zoology, Institute for Biology, Martin Luther University Halle-Wittenberg, Hoher Weg 8, 06120 Halle, Germany
  • 9 Beijing Engineering and Technology Research Center of Food Additives, Beijing Technology and Business University, Beijing 100048, China
  • 10 Institute of Apicultural Research, Chinese Academy of Agricultural Sciences, Beijing 100093, China
Toxins (Basel), 2021 11 18;13(11).
PMID: 34822594 DOI: 10.3390/toxins13110810

Abstract

Bee venom (BV) is a typical toxin secreted by stingers of honeybee workers. BV and BV therapy have long been attractive to different cultures, with extensive studies during recent decades. Nowadays, BV is applied to combat several skin diseases, such as atopic dermatitis, acne vulgaris, alopecia, vitiligo, and psoriasis. BV is used extensively in topical preparations as cosmetics and used as dressing for wound healing, as well as in facemasks. Nevertheless, the safety of BV as a therapeutic choice has always been a concern due to the immune system reaction in some people due to BV use. The documented unfavorable impact is explained by the fact that the skin reactions to BV might expand to excessive immunological responses, including anaphylaxis, that typically resolve over numerous days. This review aims to address bee venom therapeutic uses in skin cosmetics.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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