The presence of calcification in a particular FDG-avid soft tissue lesion may at times present uncertainty
regarding the clinical course of the disease pathology. Calcific deposits are not specific for either benign
or malignant aetiologies (Brant et al., 2010). Altered glucose metabolism with associated calcification
may underpin underlying aggressive pathophysiology with necrosis as sequelae. Mantle Cell Lymphoma
(MCL) is a subtype of non-Hodgkin’s lymphoma. It is a rare B-cell NHL that is prevalent in men over
the age of 60. The disease may be aggressive but it can also behave in a more indolent fashion in some
patients. MCL comprises about 5% of all NHLs. The disease is called Mantle Cell Lymphoma because the
tumour cells originally come from the ‘mantle zone’ of the lymph node (Zhou et al., 2004). Pretreatment
Hodgkin’s lymphoma with calcification may masquerade as other second primary pathologies, e.g.
extraosseous osteosarcoma or myositis ossificans (Apter et al., 2002; Korek-Amorosa et al., 1974). A
calcified perineural lymphoma prior to treatment is exceedingly rare and calcification usually occurs
one to five years after chemotherapy or radiation therapy with an incidence of 2% (Apter et al., 2002).
This case documents how the manifestation of a rare malignant perineural mantle cell lymphoma may
be indistinguishable from other pathological entities based on its pattern of distribution in a combined
FDG- PET-CT study.
Colo-colic intussusception is a rare manifestation of a primary tumour in an adult patient. This article
aims to document the rarity of colo-colic intussusception features on the 18 FDG- PET-CT in a patient
with primary colonic carcinoma. An 18 FDG-PET-CT was performed for the purpose of pretreatment
staging of a colonic carcinoma in a 61-year-old man following a diagnostic colosnoscopic biopsy. He
presented with abdominal distension and peri-rectal bleeding for a month. The fused 18 F-FDG PET-CT
image revealed an FDG-avid mass in the left hemicolon showing a rim of FDG avidity denoting the head
of intussusceptum. There are also multiple FDG-avid nodules seen along the anti-mesenteric colonic fat
suspicious for lymph nodes metastasis. Debulking of tumour revealed a mucinous adenocarcinoma of
colon with a metastatic lymph node. 18 FDG PET-CT features of intussusception in colonic carcinoma
have never been described before. It can potentially become a preferred diagnostic tool in delineating a
potential tumour mass within the intussusceptions that help improve prognosis in patients with malignancy.
A majority of the clinical use of positron emission tomography (PET)-computed tomography (CT) is related to cancer management. Its application in evaluating inflammatory diseases and pyrexia of unknown origin is becoming popular. We reviewed the fluorine-18-fluorodeoxyglucose PET-CT findings of an 80-year-old woman with nonspecific clinical presentation consisting of generalised malaise, moderately high fever and weight loss. Prior CT and magnetic resonance imaging were not helpful in providing a clinical diagnosis. The diagnosis was Horton's arteritis, and the patient responded well to high-dose steroids.
Chronic pain is a common medical issue. Beside chronic devastating pain, patients also suffer dysfunction more generally, including in the physical, emotional, social, recreational, vocational, financial, and legal spheres. Integrated multidisciplinary and multimodal chronic pain management programmes offer clear evidence for relief of suffering and return to functional lifestyles.
To establish the role of positron-emission tomography (PET)-computed tomography (CT) in post-transplant lymphoproliferative disorder (PTLD) patients, compared to conventional imaging (ultrasonography/CT/magnetic resonance imaging) in relation to its accuracy, sensitivity and specificity.