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Specific roles of strigolactones in plant physiology and remediation of heavy metals from contaminated soil

Faizan M, Cheng SH, Tonny SH, Robab MI

Plant Physiol Biochem, 2022 Dec 01;192:186-195.
PMID: 36244191 DOI: 10.1016/j.plaphy.2022.10.004

Strigolactones (SLs) have been implicated in various developmental processes of the plant, including the response against several abiotic stresses. It is well known as a class of endogenous phytohormones that regulates shoot branching, secondary growth and root morphology. This hormone facilitates plants in responding to nitrogen and phosphorus starvation by shaping the above and below ground structural design. SLs actively participate within regulatory networks of plant stress adaptation that are governed by phytohormones. Heavy metals (HMs) in soil are considered a serious environmental problem that causes various harmful effects on plants. SLs along with other plant hormones imply the role in plant architecture is far from being fully understood. Strategy to remove/remediation of HMs from the soil with the help of SLs has not been defined yet. Therefore, the present review aims to comprehensively provide an overview of SLs role in fine-tuning plant architectures, relation with other plant hormones under abiotic stress, and remediation of HMs contaminated soil using SLs.
How ICT and globalization interact with the environment: a case of the Chinese economy

Bibi M, Khan MK, Tufail MMB, Godil DI, Usman R, Faizan M

Environ Sci Pollut Res Int, 2023 Jan;30(3):8207-8225.
PMID: 36053426 DOI: 10.1007/s11356-022-22677-7

An era of rapid changes in the technological and economic aspects of developing and developed countries can have detrimental extortions on the environment around the world. From the perspective of globalization, the rapid development and growth can reroute to enhance the interaction between people, organizations, and countries across the globe including China through the usage of information and communication technology which in turn contributes to the economic growth of one side, whereas on the other side, it affects the environmental quality. Referring to this aspect, this study is focused to inspect the link between information and communication technology, and globalization with the facets of degradation in the environment that as CO2 emission and ecological footprint by keeping the view of economic growth prospects as well via using the EKC hypothesis. In our study, time-series data was employed from 1987 to 2020 for China using the Dynamic ARDL approach. Grounded on the findings of the study, economic growth from the sight of GDP fallouts in rising the emission of CO2 and EFP in the short and long run whereas GDP sqr cause decrease in the CO2 emission and EFP. Thus, this authorizes the presence of inverted U-shaped existence among GDP sqr, CO2 emission, and EFP. Therefore, this provides provision for the EKC hypothesis in China. Furthermore, ICT and globalization cause a decline in the emission of CO2 and EFP in the short and long run respectively. In combatting challenges linked to the environment, globalization, as well as ICT, is seen as a crucial factor based on the pieces of evidence in our study while the policy implications are also proposed in the paper.
Fulltext Time to Treatment Initiation and Retrospective Analysis of Antiretroviral Therapy Outcomes among HIV-positive Methadone Maintenance Therapy Clients in Primary Health-care Centers, Kuantan, Pahang

Ramlan AR, Mohamed Nazar NI, Tumian A, Ab Rahman NS, Mohamad D, Abdul Talib MS, et al.

J Pharm Bioallied Sci, 2020 Nov;12(Suppl 2):S810-S815.
PMID: 33828381 DOI: 10.4103/jpbs.JPBS_3_20

Introduction: Methadone maintenance therapy (MMT) program helped to improve access to antiretroviral therapy (ART) among people who inject drugs (PWID) with human immunodeficiency virus (HIV). However, the time to treatment initiation (TTI) and outcomes of ART intervention in this population have scarcely been analyzed.
Objectives: The aim of this study was to analyze the TTI and outcomes of ART among MMT clients in primary health-care centers in Kuantan, Pahang.
Materials and Methods: This was a retrospective evaluation of MMT clients from 2006 to 2019. The TTI was calculated from the day of MMT enrolment to ART initiation. The trends of CD4 counts and viral loads were descriptively evaluated. Cox proportional hazard model was used to analyze the survival and treatment retention rate.
Results: A total of 67 MMT clients from six primary health-care centers were HIV-positive, of which 37 clients were started on ART. The mean TTI of ART was 27 months. The clients who were given ART had a mean CD4 count of 119 cells/mm3 at baseline and increased to 219 cells/mm3 after 6 months of ART. Only two patients (5.4%) in the ART subgroup had an unsuppressed viral load. The initiation of ART had reduced the risk of death by 72.8% (hazard ratio = 0.27, P = 0.024), and they are 13.1 times more likely to remain in treatment (P < 0.01).
Conclusion: The TTI of ART was delayed in this population. MMT clients who were given ART have better CD4 and viral load outcomes, helped reduced death risk and showed higher retention rates in MMT program.
A theoretical investigation of the lead-free double perovskites halides Rb2 XCl6 (X = Se, Ti) for optoelectronic and thermoelectric applications

Al-Qaisi S, Mebed AM, Mushtaq M, Rai DP, Alrebdi TA, Sheikh RA, et al.

J Comput Chem, 2023 Jul 15;44(19):1690-1703.
PMID: 37093704 DOI: 10.1002/jcc.27119

In this study, structural, electronic, optical, thermoelectric, and thermodynamics properties of vacancy-ordered double perovskites Rb2 XCl6 (X = Se, Ti) were explored theoretically. The results revealed that Rb2SeCl6 and Rb2 TiCl6 are indirect band gap (Eg ) semiconductors with Eg values of 2.95 eV, and 2.84 eV respectively. The calculated properties (phonons, elastic constant, Poisson's ratio, and Pugh's ratio) revealed that both materials are dynamically and chemically stable and can exhibit brittle (Rb2 SeCl6 ) and ductile (Rb2 TiCl6 ) nature. From the analysis of optical parameters, it was noticed that the refractive index of the materials has a value of 1.5-2.0 where light absorption was found from the visible to the ultraviolet region. The thermoelectric properties determined by using the BoltzTrap code demonstrated that at room temperature, the Figure of merit (ZT) was found to be 0.74 and 0.76 for Rb2 SeCl6 and Rb2 TiCl6 , respectively. Despite a moderate value of ZT in such materials, further studies might explore effective methods for tuning the electronic band gap and improving the thermoelectric response of the material for practical energy production applications.