MyMedR

Displaying all 5 publications

Abstract:

Sort:

Hand-arm vibration disorder among grass-cutter workers in Malaysia

Azmir NA, Ghazali MI, Yahya MN, Ali MH

Int J Occup Saf Ergon, 2016 Apr 6.
PMID: 27050159

Prolonged exposure to hand-transmitted vibration from grass-cutting machines has been associated with increasing occurrences of symptoms and signs of occupational diseases related to hand-arm vibration syndrome (HAVS).
Spectrum of upper airway pathology in children with Down syndrome in a single tertiary centre

Yahya MN, Goh BS, Mohammad Nasseri FZ, Kamal Nor NA, Wan Md Zin WN, Abdul Latif H

Acta Otolaryngol, 2022 Feb 02.
PMID: 35107400 DOI: 10.1080/00016489.2022.2028007

BACKGROUND: Down syndrome (DS) is the most common human chromosomal genetic disorder; caused by extra copy of chromosome 21-one out of 792 babies globally and one in 950 in Malaysia.
OBJECTIVES: To obtain spectrum of upper airway pathology in DS children-prevalence, causes and management practices.
MATERIALS AND METHODS: A cross-sectional study of children with DS aged less than 18 years old with signs of UAO was conducted. Diagnosis of UAO, management and final outcome was observed and documented.
RESULTS: Ninety-one patients were recruited. 20 cases (22%) had significant noisy breathing which indicates the prevalence of upper airway pathology (p=.025). Laryngomalacia (34.5%) was the most common pathology, followed by paediatric SDB (24.1%), tracheal bronchus (17.2%), tracheal stenosis (6.9%), and tracheomalacia (6.9%). Seven cases (7.7%) presented with respiratory distress. 12 cases were managed conservatively, while eight cases required further investigations under general anaesthesia (GA) with/without surgical intervention. Six cases showed symptoms resolution within a week post-surgical intervention, and another case resolved after 30 days and one case resolved after 8 months of post-surgical intervention.
CONCLUSION AND SIGNIFICANCE: Early detection and high index of suspicion is required to diagnose and treat these anomalies timely.
Fulltext Effect of Salinity on Hydroxyapatite Nanoparticles Flooding in Enhanced Oil Recovery: A Mechanistic Study

Ngouangna EN, Jaafar MZ, Norddin M, Agi A, Yakasai F, Oseh JO, et al.

ACS Omega, 2023 May 23;8(20):17819-17833.
PMID: 37251146 DOI: 10.1021/acsomega.3c00695

Fluid-fluid interactions can affect any enhanced oil recovery (EOR) method, including nanofluid (NF) brine-water flooding. Flooding with NFs changes wettability and lowers oil-water interfacial tension (IFT). Preparation and modification affect the nanoparticle (NP) performance. Hydroxyapatite (HAP) NPs in EOR are yet to be properly verified. HAP was synthesized in this study using co-precipitation and in situ surface functionalization with sodium dodecyl sulfate in order to investigate its impact on EOR processes at high temperatures and different salinities. The following techniques were employed, in that sequence, to verify its synthesis: transmission electron microscopy, zeta potential, thermogravimetric analysis, Fourier transform infrared spectroscopy, X-ray diffraction, particle size analysis, and energy-dispersive X-ray spectra. The outcomes showed the production of HAP, with the particles being evenly dispersed and stable in aqueous solution. The particles' surface charge increased from -5 to -27 mV when the pH was changed from 1 to 13. The HAP NFs at 0.1 wt % altered the wettability of sandstone core plugs from oil-wet at 111.7 to water-wet at 9.0 contact angles at salinity ranges of 5000 ppm to 30,000 ppm. Additionally, the IFT was reduced to 3 mN/m HAP with an incremental oil recovery of 17.9% of the initial oil in place. The HAP NF thus demonstrated excellent effectiveness in EOR through IFT reduction, wettability change, and oil displacement in both low and high salinity conditions.
Antioxidant activity and phenolic profile of various morphological parts of underutilised Baccaurea angulata fruit

Ahmed IA, Mikail MA, Bin Ibrahim M, Bin Hazali N, Rasad MS, Ghani RA, et al.

Food Chem, 2015 Apr 1;172:778-87.
PMID: 25442620 DOI: 10.1016/j.foodchem.2014.09.122

Baccaurea angulata is an underutilised tropical fruit of Borneo Island of Malaysia. The effect of solvents was examined on yield, total phenolic (TPC), total flavonoids (TFC), total carotene content (TCC), free radical scavenging activities and lipid peroxidation inhibition activities. The results indicated that the pulp (edible portion) had the highest yield, while methanol extracts were significantly (p < 0.01) found to contain higher TPC, TFC and TCC than phosphate buffered saline (PBS) extracts for all the fruits parts. The methanol extracts also showed remarkable antiradical activity and significant lipid peroxidation inhibition activities, with their IC50 results highly comparable to that of commercial blueberry. The variations in the results among the extracts suggest different interactions, such as negative or antagonistic (interference), additive and synergistic effect interactions. The study indicated that B. angulata like other underutilised tropical fruits contained remarkable primary antioxidants. Thus, the fruit has the potential to be sources of antioxidant components.
Baccaurea angulata fruit inhibits lipid peroxidation and induces the increase in antioxidant enzyme activities

Mikail MA, Ahmed IA, Ibrahim M, Hazali N, Abdul Rasad MS, Abdul Ghani R, et al.

Eur J Nutr, 2016 Jun;55(4):1435-44.
PMID: 26091909 DOI: 10.1007/s00394-015-0961-7

PURPOSE: The consequence of the increased demand due to the population expansion has put tremendous pressure on the natural supply of fruits. Hence, there is an unprecedented growing interest in the exploration of the potentials of underutilized fruits as alternatives to the commercially available fruits. Baccaurea angulata is an underutilized fruit widely distributed in Borneo Island of Malaysia. The present study was conducted to investigate the effects of B. angulata whole fruit (WF), skin (SK) and pulp (PL) juices on malondialdehyde (MDA) levels and antioxidant enzymes in rabbits fed high-cholesterol diet.
METHODS: Thirty-six male rabbits of New Zealand strain were randomly assigned to six groups. Rabbits were fed either a standard pellet (group NC) or a high-cholesterol diet (groups HC, PC, WF, SK and PL). Groups WF, SK and PL were also given 1 ml/kg/day B. angulata WF, SK and PL juices, respectively.
RESULTS: Baccaurea angulata had high antioxidant activities. The administration of the various juices significantly reduced (p