Displaying all 3 publications

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  1. Yasin ZAM, Ibrahim F, Rashid NN, Razif MFM, Yusof R
    Curr Pharm Biotechnol, 2017;18(11):864-876.
    PMID: 29256348 DOI: 10.2174/1389201019666171219105920
    BACKGROUND: Skin is the largest and most visible organ of the body. Many of its functions include temperature regulation, immunity from microorganisms, maintaining electrolyte balance, and protection from physical injuries, chemical agents and ultraviolet (UV) radiation. Aging occurs in every layer of the skin, primarily due to the degradation of its components. Induction of degradative enzymes and the abundant production of reactive oxygen species lead to skin aging. Understanding the complexity of skin structure and factors contributing to the skin aging will help us impede the aging process. Applications of anti-aging products are a common method to prevent or repair damages that lead to aging.

    CONCLUSION: This review will provide information on the causes and indicators of skin aging as well as examine studies that have used plants to produce anti-aging products.

    Matched MeSH terms: Skin Physiological Phenomena/drug effects
  2. Nour S, Imani R, Chaudhry GR, Sharifi AM
    J Biomed Mater Res A, 2021 04;109(4):453-478.
    PMID: 32985051 DOI: 10.1002/jbm.a.37105
    Skin injuries and in particular, chronic wounds, are one of the major prevalent medical problems, worldwide. Due to the pivotal role of angiogenesis in tissue regeneration, impaired angiogenesis can cause several complications during the wound healing process and skin regeneration. Therefore, induction or promotion of angiogenesis can be considered as a promising approach to accelerate wound healing. This article presents a comprehensive overview of current and emerging angiogenesis induction methods applied in several studies for skin regeneration, which are classified into the cell, growth factor, scaffold, and biological/chemical compound-based strategies. In addition, the advantages and disadvantages of these angiogenic strategies along with related research examples are discussed in order to demonstrate their potential in the treatment of wounds.
    Matched MeSH terms: Skin Physiological Phenomena/drug effects
  3. Abdul Rahim N, Makpol S, Chua KH, Yusof YA, Top GM, Ngah WZ
    Med J Malaysia, 2008 Jul;63 Suppl A:71-2.
    PMID: 19024989
    Stress-induced premature senescence (SIPS) model is in vitro model of cellular aging. In this study, apoptosis was evaluated in SIPS model and in replicative senescent fibroblasts. We also compared the activity of senescence-associated beta-galactosidase (SA-beta gal) as a biomarker of cellular aging. Our results suggested that SIPS model and senescent fibroblasts might share similar mechanism of aging and apoptosis pathway.
    Matched MeSH terms: Skin Physiological Phenomena/drug effects*
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