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Fulltext Transport infrastructure, economic growth, and transport CO2 emissions nexus: Does green energy consumption in the transport sector matter?

Dai J, Alvarado R, Ali S, Ahmed Z, Meo MS

Environ Sci Pollut Res Int, 2023 Mar;30(14):40094-40106.
PMID: 36607580 DOI: 10.1007/s11356-022-25100-3

Attaining Sustainable Development Goals (SDGs) is important to control the adverse impacts of climate change and achieve sustainable development. Among the 17 SDGs, target 13 emphasizes enhancing urgent actions to combat climate-related changes. This target is also dependent on target 7, which advocates enhancing access to cheap alternative sustainable energy. To accomplish these targets, it is vital to curb the transport CO2 emissions (TCO2) which increased by approximately 80% from 1990 to 2019. Thus, this study assesses the role of transport renewable energy consumption (TRN) in TCO2 by taking into consideration transport fossil fuel consumption (TTF) and road infrastructure (RF) from 1970 to 2019 for the United States (US) with the intention to suggest some suitable mitigation policies. Also, this study assessed the presence of transport environmental Kuznets curve (EKC) to assess the direction of transport-induced growth. The study used the Bayer-Hanck cointegration test which utilizes four different cointegration techniques to decide cointegration along with the Gradual Shift causality test which considers structural shift and fractional integration in time series data. The long-run findings of the Dynamic Ordinary Least Squares (DOLS) test, which counters endogeneity and serial correlation, revealed that the transport renewable energy use mitigates as well as Granger causes TCO2. However, transport fossil fuel usage and road infrastructure enhance TCO2. Surprisingly, the transport EKC is invalid in the case of the US, and increased growth levels are harmful to the environment. The association between TCO2 and economic growth is similar to a U-shaped curve. The Spectral Causality test revealed the growth hypothesis regarding transport fossil fuel use and economic growth connection, which suggests that policymakers should be cautious while decreasing the usage of transport fossil fuels because it may hamper economic progress. These findings call for revisiting growth strategies and increasing green energy utilization in the transport sector to mitigate transport emissions.
Examining the role of gender diversity on ownership structure-sustainable performance nexus: fresh evidence from emerging markets

Karim S, Naeem MA, Meero AA, Rabbani MR

Environ Sci Pollut Res Int, 2023 Mar;30(15):42829-42844.
PMID: 34826080 DOI: 10.1007/s11356-021-17459-6

The current research presents fresh insights on empirically presenting the relationship between ownership structure and corporate sustainable performance of two emerging markets: Malaysia and Pakistan. Moreover, the moderating role of gender diversity is observed on the relationship between ownership structure and corporate sustainable performance. Dynamic estimator, named system generalized method of moments, is used for estimations that control for potential dynamic endogeneity, simultaneity, and reverse causality. Findings reveal that ownership concentration and state ownership are negatively related to economic, social, and environmental indicators of CSP both in Malaysia and Pakistan, whereas directors' ownership is positively associated with all sustainability indicators. Financial institution's ownership showed a positive significant impact on CSP in Malaysia, whereas an insignificant relationship is observed in Pakistan. Meanwhile, the moderating impact of women directors on the relationship between ownership structure and corporate sustainable performance reveals a significant impact in Malaysia and an insignificant impact in Pakistan. Generally, the findings of the study have practical implications for regulatory authorities, securities commissions, and policymakers of Malaysia and Pakistan. Moreover, there is a need to bring reforms into corporate governance structures in Pakistan, where weak economic conditions leave a frail impact of ownership structure on CSP and an insignificant moderating impact of board gender diversity.
Fulltext Dataset from dried blood spot acylcarnitine for detection of Carnitine-Acylcarnitine Translocase (CACT) deficiency and Carnitine Palmitoyl Transferase 2 (CPT2) deficiency

Habib A, Nazri MIBA, Rahman SA

Data Brief, 2023 Jun;48:109090.
PMID: 37020897 DOI: 10.1016/j.dib.2023.109090

Clinical diagnosis of inborn errors of metabolism in the suspected patients is usually guided by the initial general investigations in the laboratory such as the concentration of ammonia, blood gases status, blood glucose and ketones. The establishment of a biochemical diagnosis in patients with inborn errors of metabolism depends on the detection of the specific metabolites in the abnormal metabolic pathway which can appear in any of the body fluids but are most commonly tested in blood and urine samples. Acylcarnitine and/or acylcarnitine ratio in patients with carnitine acylcarnitine translocase and carnitine palmitoyl transferase deficiency showed an abnormal profile regardless of the metabolic status of patients. The acylcarnitine was derived from the analysis of dried blood spot using multiple reaction monitoring (MRM) which was performed using quadrupole mass spectrometry. The dataset presented in this article was generated from analysis of acylcarnitines in the 17,121 dried blood spots from symptomatic Malaysian patients less than fifty years old who exhibited symptoms suggestive of inborn errors of metabolism, but had a normal acylcarnitine profile. A precursor or ion scan of m/z 85 was selected for the analysis. Quantification of each analyte was obtained using the signal intensity ratio of the acylcarnitine to its internal standard. The acylcarnitines analyzed included C0, C2, C3, C3DC, C4, C5, C5:1, C5DC, C5OH, C6, C8, C10, C12, C14, C16, C18, C18:1, C16OH, C18OH and C18:1OH and was analyzed using Neolynx V4.0 software. We decided to choose the 1st and 99th percentiles as the minimum and maximum cut-offs. The filtered part of data in this article was used in the article Novel mutations associated with Carnitine-Acylcarnitine Translocase and Carnitine Palmitoyl Transferase 2 deficiencies in Malaysia. This dataset is intended to enable the scientific communities to get access to the raw dataset for future translational research use in inborn errors of metabolism as very few acylcarnitine data was developed and published for the symptomatic patients suspected of inborn errors of metabolism especially in the Asian population.
Fulltext Effect of Carcinomas on Autosomal Trait Screening: A Review Article

Alhatim H, Abdullah MNH, Abu Bakar S, Amer SA

Curr Issues Mol Biol, 2023 Sep 04;45(9):7275-7285.
PMID: 37754244 DOI: 10.3390/cimb45090460

This review highlights the effect of carcinomas on the results of the examination of autosomal genetic traits for identification and paternity tests when carcinoid tissue is the only source and no other samples are available. In DNA typing or genetic fingerprinting, variable elements are isolated and identified within the base pair sequences that form the DNA. The person's probable identity can be determined by analysing nucleotide sequences in particular regions of DNA unique to everyone. Genetics plays an increasingly important role in the risk stratification and management of carcinoma patients. The available information from previous studies has indicated that in some incidents, including mass disasters and crimes such as terrorist incidents, biological evidence may not be available at the scene of the accident, except for some unknown human remains found in the form of undefined human tissues. If these tissues have cancerous tumours, it may affect the examination of the genetic traits derived from these samples, thereby resulting in a failure to identify the person. Pathology units, more often, verify the identity of the patients who were diagnosed with cancer in reference to their deceased tumorous relatives. Genetic fingerprinting (GF) is also used in paternity testing when the alleged parent disappeared or died and earlier was diagnosed and treated for cancer.
The Impact of Laparoscopic Intraperitoneal Instillation of Ropivacaine in Enhancing Respiratory Recovery and Reducing Acute Postoperative Pain in Laparoscopic Sleeve Gastrectomy: a Double-Blinded Randomised Control; RELiEVE Trial

Zheng LQ, Kosai NR, Ani MFC, Maaya M

Obes Surg, 2023 Oct;33(10):3141-3146.
PMID: 37667104 DOI: 10.1007/s11695-023-06777-y

PURPOSE: Laparoscopic intraperitoneal instillation of local anaesthetic in bariatric surgery proven to reduce postoperative pain. Limited data are available regarding the use of instillation ropivacaine and its impact on the recovery of respiratory effort. This study aims to evaluate the efficacy of laparoscopic intraperitoneal instillation of ropivacaine in reducing acute postoperative pain and enhancing the recovery of respiratory effort in laparoscopic sleeve gastrectomy.
MATERIALS AND METHODS: This double-blinded RCT enrolled 110 patients who underwent laparoscopic sleeve gastrectomy at Hospital Canselor Tuanku Muhriz UKM from November 2020 to May 2021. Any patients with previous abdominal surgery, chronic kidney disease, or liver disease were excluded. The patients were randomised into two groups: (i) the IPLA group which received ropivacaine intraperitoneal instillation at the dissected left crus and (ii) the placebo group (sterile water instillation). Perioperative analgesia was standardised. The first 24-h postoperative pain was assessed using a VAS. The respiratory effort was assessed using incentive spirometry simultaneously.
RESULTS: Total of 110 patients were recruited. The VAS score was lower with an enhanced recovery of respiratory effort in the local anaesthetic group compared to the placebo group (P < 0.05) within the first 24 h postoperatively. In addition, the placebo group required additional postoperative analgesia (P < 0.05). No side effects were reported with the use of intraperitoneal instillation of ropivacaine.
CONCLUSION: The use of intraperitoneal instillation of ropivacaine in laparoscopic sleeve gastrectomy is recommended as it is safe, effectively reduces acute postoperative pain, and enhances the recovery of respiratory effort postoperatively.
Fulltext A rare presentation of a gastric volvulus in an adult Bochdalek hernia: a case report

Azhar A, Karim ZRA, Aripin YM, Abid Amir M

J Surg Case Rep, 2023 Sep;2023(9):rjad540.
PMID: 37790291 DOI: 10.1093/jscr/rjad540

A Bochdalek hernia is a common congenital diaphragmatic defect in infants. A late presentation during adulthood is rare with misleading signs and symptoms, resulting in misdiagnosis and errors in treatment. We describe a 30-year-old man who presented with abdominal pain and chronic choking sensation, which was previously treated as peptic ulcer disease. During the present admission, radiological imaging performed revealed loops of bowel and a gastric volvulus in the left hemithorax. The patient underwent a successful emergency surgery and repair of a Bochdalek hernia. Due to its rarity and ambiguous presentation, a symptomatic Bochdalek hernia in an adult is commonly misdiagnosed. A comprehensive evaluation is pertinent for early diagnosis and treatment, to prevent complications arising from obstruction and strangulation of herniated intraabdominal contents.
Capital structure determinants across sectors: Comparison of observed evidences from the use of time series and panel data estimators

Rehan R, Abdul Hadi AR, Hussain HI, Adnan Hye QM

Heliyon, 2023 Sep;9(9):e19618.
PMID: 37810001 DOI: 10.1016/j.heliyon.2023.e19618

This comparative study is an attempt to explore the determinants of capital structure for Malaysian firms listed in various sectors level. Within the framework of traditional and moderate dynamic capital structure theories, the key determinants such as fixed assets, current assets, return on equity, size, earning per share and total assets are tested in relation to the debt-equity ratio. The large-scale study entails data collected from 551 listed firms of Bursa Malaysia main market over 12 years period i.e. 2005-2016. Notably, this study combines Time Series econometrics with Panel Data analysis to enhance methodological robustness. Moreover, the comparative analysis approach is designated to recognize the most persistent capital structure determinants. In the first place, the Multiple Regression analysis (MRA) is selected as a baseline estimation method. Subsequently, the Auto Regression Distributed Lag model (ARDL), the Panel Data Static models, and Dynamic model via the Generalized Method of Moments (GMM) are employed to identify the capital structure determinants for the firms listed at Bursa Malaysia. The outcomes are surprising and indicate that the entire market is primarily controlled by the studied determinant total assets, which is significant in both construction and property sectors through MRA, ARDL, and GMM analysis. Technically, the significant role of tangibility and the existence of speed of adjustment across sectors imply that the Dynamic Capital Structure is the most prominent among all, followed by the Dynamic Trade-off theory.
The determinants of carbon emissions in Belt and Road Initiative countries: analyzing the interactive role of information and communication technologies

Ji D, Sibt-E-Ali M, Amin A, Ayub B

Environ Sci Pollut Res Int, 2023 Oct;30(46):103198-103211.
PMID: 37682436 DOI: 10.1007/s11356-023-29719-8

Belt and Road Initiative (BRI) countries have benefited greatly from the intelligent growth of the green economy made possible by the widespread adoption of internet and mobile phone technologies. In addition, renewable energy consumption endorses sustainable development. Therefore, the purpose of this research is to determine if the use of information and communication technology (ICT) and renewable energy consumption has an effect on sustainable development in BRI countries, while using the augmented mean group (AMG) model, AMG robustness test, and panel Dumitrescu-Hurlin causality test to get robust results. According to the results of the study, the information and communication technology, renewable consumption, human capital, and urbanization reduces the emission of carbon dioxide emission in BRI countries while economic growth enhances the CO2 emission. Therefore, it is recommended that BRI countries increase their inter-regional cooperation in order to boost investment in renewable energy, effectively use the spillover effect of technology and knowledge, and end the resource curse in environmental policy. Based on the results, the authors of this paper propose a number of important steps toward environmental sustainability.
Personality assessment in military - Bright and dark sides of the assessment measures: A review

Sohail M, Naeem F, Javaid MU, Ibikunle AK

Work, 2023;76(3):979-990.
PMID: 37182851 DOI: 10.3233/WOR-220454

BACKGROUND: Personality assessment has its own bright and dark sides, especially in the military setting. It is at play since the emergence of clinical psychology and its application in the recruitment process during World War I and II. Change in personality assessment trends, the evolution of complex personality traits, and changing geopolitical settings across the world necessitate the development of cost-effective, time-efficient, and reliable assessment measures that overcome issues in current assessment measures and fulfil the needs of present timesOBJECTIVE:The objective of this paper is to explore the evolution of personality assessment measures and their uses in military settings along with the comparison of self-report and non-self-report measures. It would give directions for the development of new measures to overcome the issues and drawbacks associated with current measures of research.
METHODS: The research question was formulated using the most valid SPIDER technique for a comprehensive search. PubMed, Google Scholar, and PsycNet databases were searched. 19 articles were selected based on inclusion and exclusion criteria out of 775 articles.
RESULTS: Thematic analyses show that personality assessment in the military is done to a) detect psychopathology, b) detect aberrant responses, c) recruit new personnel, d) predict training and performance outcomes, and e) predict leadership. The research contributes to the body of knowledge by showing an integrated picture of the most widely used assessment tools and the purpose it serves.
CONCLUSION: There is a need to develop assessment measures that are culture free and can assess more complex personality attributes.
The new wave of Congo virus in Pakistan: emerging threat

Masood I, Tahir MJ, Naeem A, Shrateh ON, Ahmed A

Trop Med Health, 2023 Nov 14;51(1):62.
PMID: 37957782 DOI: 10.1186/s41182-023-00559-z

Congo virus, or Crimean-Congo hemorrhagic fever (CCHF), is a tick-borne disease caused by a single-stranded RNA virus (genus nairovirus, Bunyaviridae family). It spreads through infected ticks' bites or contact with viremic individuals or livestock. Factors supporting its spread include hot, humid climates, limited pesticide use, poor animal control, inadequate irrigation during monsoons, and vector control deficiencies. Nosocomial transmission in under-resourced hospitals poses a threat to healthcare workers. Decades of CCHF cases persist in Pakistan due to these factors, with six deaths reported by June 2023. To combat the epidemic, Pakistan should raise awareness, improve irrigation, establish surveillance systems, and implement livestock quarantine and vaccination.
Nitrate and Nitrogen Oxides: Sources, Health Effects and Their Remediation

Hakeem KR, Sabir M, Ozturk M, Akhtar MS, Ibrahim FH

Rev Environ Contam Toxicol, 2017;242:183-217.
PMID: 27734212 DOI: 10.1007/398_2016_11

Increased use of nitrogenous (N) fertilizers in agriculture has significantly altered the global N-cycle because they release nitrogenous gases of environmental concerns. The emission of nitrous oxide (N2O) contributes to the global greenhouse gas accumulation and the stratospheric ozone depletion. In addition, it causes nitrate leaching problem deteriorating ground water quality. The nitrate toxicity has been reported in a number of studies showing the health hazards like methemoglobinemia in infants and is a potent cause of cancer. Despite these evident negative environmental as well as health impacts, consumption of N fertilizer cannot be reduced in view of the food security for the teeming growing world population. Various agronomic and genetic modifications have been practiced to tackle this problem. Some agronomic techniques adopted include split application of N, use of slow-release fertilizers, nitrification inhibitors and encouraging the use of organic manure over chemical fertilizers. As a matter of fact, the use of chemical means to remediate nitrate from the environment is very difficult and costly. Particularly, removal of nitrate from water is difficult task because it is chemically non-reactive in dilute aqueous solutions. Hence, the use of biological means for nitrate remediation offers a promising strategy to minimize the ill effects of nitrates and nitrites. One of the important goals to reduce N-fertilizer application can be effectively achieved by choosing N-efficient genotypes. This will ensure the optimum uptake of applied N in a balanced manner and exploring the molecular mechanisms for their uptake as well as metabolism in assimilatory pathways. The objectives of this paper are to evaluate the interrelations which exist in the terrestrial ecosystems between the plant type and characteristics of nutrient uptake and analyze the global consumption and demand for fertilizer nitrogen in relation to cereal production, evaluate the various methods used to determine nitrogen use efficincy (NUE), determine NUE for the major cereals grown across large agroclimatic regions, determine the key factors that control NUE, and finally analyze various strategies available to improve the use efficiency of fertilizer nitrogen.
Fulltext Andaliman (Zanthoxylum acanthopodium DC.) a herbal medicine from North Sumatera, Indonesia: Phytochemical and pharmacological review

Adrian, Syahputra RA, Juwita NA, Astyka R, Lubis MF

Heliyon, 2023 May;9(5):e16159.
PMID: 37251868 DOI: 10.1016/j.heliyon.2023.e16159

Andaliman (Z. acanthopodium DC) is a kind of flowering plant that belongs to the Rutaceae family. The habitats are found in southwestern China (Guangxi, Guizhou, Sichuan, Tibet, and Yunnan), Bangladesh, Bhutan, northern India, and northeastern India (Arunachal Pradesh, Assam, Manipur, Meghalaya, Nagaland, Sikkim, Uttar Pradesh, and West Bengal), Nepal, Laos, Burma, Vietnam, North Sumatra highlands, Peninsular Malaysia, and northern Thailand. Andaliman is indigenous to North Sumatra, more specifically the Toba Samosir District, North Tapanuli, and the Dairi region. The phytochemical investigation showed some terpenoids as well as other compounds such as alkaloids, flavonoids, glycosides, tannins, and saponins, but they have not been entirely identified. In Indonesia, the plant is employed both in the culinary industry as an additive for flavoring food and in the traditional medical system for treating various diseases. It was reported to possess antibacterial, antifungal, anti-inflammatory, anticancer, cardioprotective, hepatoprotective, nephroprotective, and wound healing properties, alongside other activities related to pregnancy that were tested in vitro and in vivo. The results of the investigation were based on previously published studies. This review serves as information and a summary, thereby making further exploration of Andaliman to be easier.
Fulltext Overview of Electrospinning for Tissue Engineering Applications

Zulkifli MZA, Nordin D, Shaari N, Kamarudin SK

Polymers (Basel), 2023 May 23;15(11).
PMID: 37299217 DOI: 10.3390/polym15112418

Tissue engineering (TE) is an emerging field of study that incorporates the principles of biology, medicine, and engineering for designing biological substitutes to maintain, restore, or improve tissue functions with the goal of avoiding organ transplantation. Amongst the various scaffolding techniques, electrospinning is one of the most widely used techniques to synthesise a nanofibrous scaffold. Electrospinning as a potential tissue engineering scaffolding technique has attracted a great deal of interest and has been widely discussed in many studies. The high surface-to-volume ratio of nanofibres, coupled with their ability to fabricate scaffolds that may mimic extracellular matrices, facilitates cell migration, proliferation, adhesion, and differentiation. These are all very desirable properties for TE applications. However, despite its widespread use and distinct advantages, electrospun scaffolds suffer from two major practical limitations: poor cell penetration and poor load-bearing applications. Furthermore, electrospun scaffolds have low mechanical strength. Several solutions have been offered by various research groups to overcome these limitations. This review provides an overview of the electrospinning techniques used to synthesise nanofibres for TE applications. In addition, we describe current research on nanofibre fabrication and characterisation, including the main limitations of electrospinning and some possible solutions to overcome these limitations.
Fulltext Factors affecting repurchase intention of organic food among generation Z (Evidence from developing economy)

Bhutto MY, Khan MA, Sun C, Hashim S, Khan HT

PLoS One, 2023;18(3):e0281527.
PMID: 36961791 DOI: 10.1371/journal.pone.0281527

Organic food has gained much importance due to consumers' rising environmental and health concerns. Purchase intention of organic food has been explored widely, but the repurchase intention of organic food has gained little attention among researchers. So, it has become important to explore repurchase intention among generation Z; a generation considered more educated and aware of rising environmental concerns. Generation Z is more tech-savvy and brand conscious, so its impact on repurchase intention through consumer satisfaction has been explored. The data in this paper was collected from 400 respondents through a structured questionnaire in Islamabad, Pakistan. We used the PLS-SEM approach for data analysis and results; we found that social media influence and brand purchase impact brand awareness and positively impact brand awareness on consumer satisfaction. Moreover, it is also found that consumer satisfaction positively impacts the repurchase intention of organic food. Our study found that Generation Z has a strong social media influence, so marketers' managers must consider and address the issues when consumers consider social media for their concerns and suggestion.
An unexpected presentation of very severe hypertriglyceridemia in a boy with Coffin-Lowry syndrome: a case report

Tan SL, Ahmad Narihan MGB, Koa AJ

BMC Pediatr, 2023 Oct 28;23(1):541.
PMID: 37898736 DOI: 10.1186/s12887-023-04376-5

BACKGROUND: Coffin-Lowry syndrome (CLS) is a rare X-linked condition with intellectual disability, growth retardation, characteristic facies and skeletal anomalies. To date, hypertriglyceridemia has not been reported in literature to be associated with CLS.
CASE PRESENTATION: Herein, we report a case of very severe hypertriglyceridemia 32 mmol/L (2834 mg/dL) detected incidentally at three months old in an otherwise well boy born late preterm with intrauterine growth restriction, when he presented with lipaemic plasma. He was later diagnosed with CLS. No pathogenic mutations were found for hypertriglyceridemia, and no secondary causes could explain his very severe hypertriglyceridemia.
CONCLUSIONS: The very severe hypertriglyceridemia in this case may appear to be a serious presentation of an unrecognised clinical feature of CLS, further expanding its phenotype.
Fulltext A Comprehensive Review on the Applications of Exosomes and Liposomes in Regenerative Medicine and Tissue Engineering

Shafiei M, Ansari MNM, Razak SIA, Khan MUA

Polymers (Basel), 2021 Jul 30;13(15).
PMID: 34372132 DOI: 10.3390/polym13152529

Tissue engineering and regenerative medicine are generally concerned with reconstructing cells, tissues, or organs to restore typical biological characteristics. Liposomes are round vesicles with a hydrophilic center and bilayers of amphiphiles which are the most influential family of nanomedicine. Liposomes have extensive research, engineering, and medicine uses, particularly in a drug delivery system, genes, and vaccines for treatments. Exosomes are extracellular vesicles (EVs) that carry various biomolecular cargos such as miRNA, mRNA, DNA, and proteins. As exosomal cargo changes with adjustments in parent cells and position, research of exosomal cargo constituents provides a rare chance for sicknesses prognosis and care. Exosomes have a more substantial degree of bioactivity and immunogenicity than liposomes as they are distinctly chiefly formed by cells, which improves their steadiness in the bloodstream, and enhances their absorption potential and medicinal effectiveness in vitro and in vivo. In this review, the crucial challenges of exosome and liposome science and their functions in disease improvement and therapeutic applications in tissue engineering and regenerative medicine strategies are prominently highlighted.
Leptin and calorie intake among different nicotine dependent groups

Suhaimi MZ, Sanip Z, Jan HJ, Yusoff HM

Ann Saudi Med, 2016;36(6):404-408.
PMID: 27920412

BACKGROUND: Exposure to nicotine via tobacco smoking may influence leptin release and decrease food intake among smokers. However, the effect of nicotine exposure on leptin and food intake among different nicotine dependent groups is unclear.
OBJECTIVE: We aimed to measure leptin and calorie intake among different nicotine dependent groups.
DESIGN: Cross-sectional study.
SETTING: Research department in school of medical sciences.
PATIENTS AND METHODS: Subjects were selected by purposive (non-probability) sampling and categorized as having low, moderate and high nicotine dependency based on the Fagerstrom Test for Nicotine Dependence (FTND) score. Diet was recorded by interview. Anthropometry, blood pressure, body composition, lipid profile, and physical activity level were measured accordingly. Fasting serum leptin was measured using a commercial ELISA kit.
MAIN OUTCOME MEASURE(S): Nicotine dependency, 24-hour diet, clinical anthropometric and clinical measurements.
RESULTS: In 107 Malay male smokers leptin concentration was inversely correlated with nicotine dependence. However, body weight, smoking period, blood pressure, body composition, lipid profile and physical activity level were not significantly different among low, moderately and highly dependent smoking groups. Leptin concentration and total calorie intake were also not significantly different among these groups.
CONCLUSION: Leptin concentration was inversely correlated with nicotine dependence, but leptin concentration and total calorie intake status were not significantly different among our different nicotine dependency subjects.
LIMITATIONS: Purposive sampling for subject recruitment and inaccurate information in the self-administered questionnaire.
Vitex doniana seed activated carbon for methylene blue adsorption: equilibrium and kinetics

Francis AO, Kevin OS, Ahmad Zaini MA

Int J Phytoremediation, 2023;25(12):1625-1635.
PMID: 36823750 DOI: 10.1080/15226514.2023.2179013

This study evaluated the characteristics of zinc chloride modified vitex doniana seed activated carbon (VDZnCl2) for the removal of methylene blue. VDZnCl2 was characterized for textural properties, surface morphology and surface chemistry. Batch adsorption of methylene blue by VDZnCl2 was evaluated for the effects of concentration, contact time, adsorbent dosage, and solution pH. The surface area increased from 14 to 933 m2/g with porous texture to facilitate adsorption. The SEM micrograph showed varieties of pores with widened cavities. The FTIR spectra showed the characteristics of O-H and C=C groups commonly found in carbonaceous materials. The maximum methylene blue adsorption was recorded as 238 mg/g at concentration range of 1-800 mg/L and VDZnCl2 dosage of 50 mg. Sips isotherm fitted well with the equilibrium data, suggesting that the adsorption by VDZnCl2 was a physical process onto its heterogeneous surface, while the applicability of pseudo-first-order kinetics implies that external diffusion was the rate controlling mechanism. The performance put up by VDZnCl2 suggested that it is a potential adsorbent substitute for dye wastewater treatment.
Fulltext First record of the genus Passiena (Araneae, Lycosidae) from China, with the first description of the male of P.spinicrus Thorell, 1890 from Malaysia

Tan B, Irfan M, Zhang ZS, Wang LY

Zookeys, 2023;1182:1-9.
PMID: 37868119 DOI: 10.3897/zookeys.1182.109532

The genus Passiena is recorded for the first time from China with Passienaduanisp. nov. (♂♀) from Guangxi described here. In addition, the male of P.spinicrus Thorell, 1890 is described for the first time based on a specimen from Malaysia and colour photographs of freshly collected material are also presented. Detailed morphological descriptions, photographs, genital illustrations, and a distribution map for the two species are provided.
Fulltext Effect of Nigella sativa and its bioactive compound on type 2 epithelial to mesenchymal transition: a systematic review

Nordin A, Kamal H, Yazid MD, Saim A, Idrus R

BMC Complement Altern Med, 2019 Oct 30;19(1):290.
PMID: 31666058 DOI: 10.1186/s12906-019-2706-2

BACKGROUND: Nigella sativa or commonly known as black seed or black cumin is one of the most ubiquitous complementary medicine. Epithelial to mesenchymal transition (EMT) of type 2 is defined by the balance between wound healing and tissue fibrosis, which is dependent to the state of inflammation. This systematic review is conducted to provide an overview regarding the reported effect of Nigella sativa and its bioactive compound on the type 2 EMT.
METHODS: A search was done in EBSCOHOST, OVID and SCOPUS database to obtain potentially relevant articles that were published between 1823 and August 2019. This review includes studies that focus on the effect of Nigella sativa and its bioactive compound on the events related to type 2 EMT.
RESULTS: A total of 1393 research articles were found to be potentially related to the effect of Nigella sativa and its bioactive compound, thymoquinone on Type 2 EMT. After screening was done, 22 research articles met inclusion criteria and were included in this review. Majority of the studies, reported better wound healing rate or significant prevention of tissue inflammation and organ fibrosis following Nigella sativa or thymoquinone treatments. In terms of wound healing, studies included reported progression of EMT related pathological changes after treatment with Nigella sativa or thymoquinone. Alternatively, in terms of fibrosis and inflammation, studies included reported reversal of pathological changes related to EMT after treatment with Nigella sativa or thymoquinone.
CONCLUSION: Through this review, Nigella sativa and thymoquinone have been associated with events in Type 2 EMT. They have been shown to promote wound healing, attenuate tissue inflammation, and prevent organ fibrosis via regulation of the EMT process.

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