Displaying publications 381 - 400 of 1500 in total

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  1. Fulltext ‘Sub-superscan’ in bone scan – an important feature of extensive bone metastases
    Khadijah Abdul Hamid, Mohammad Nazri Md Shah
    Malaysian Journal of Medicine and Health Sciences, 2020;16(102):75-77.
    MyJurnal
    A Superscan is described as a ‘beautiful bone scan’. In a superscan, the uptake of 99mTc-Methelene Diphosphonate (MDP) is prominent in the skeleton relative to soft tissue with absent or faint visualisation of the kidneys. This finding could be misinterpreted as a normal bone scan. A ‘Sub-superscan’ is a term used for scan findings in which the up- take is atypical of a superscan, but the patient has extensive bone metastases, as presented in our case report.
    Matched MeSH terms: Tomography, X-Ray Computed
  2. Significance of Nasal Septum Angulation and Its Association with Rhinosinusitis Symptom Scores
    Lazim NM, Abdullah AM, Abdullah B, Ismail ZIM
    Medeni Med J, 2019;34(4):333-339.
    PMID: 32821458 DOI: 10.5222/MMJ.2019.25986
    Objective: The aim of the study was to determine the association of angulation of nasal septum with the severity of rhinosinusitis as measured by symptom score and Visual Analog Score (VAS).

    Method: The study was performed as a cross sectional study conducted at two different centres in Malaysia. Ninety-eight patients who were diagnosed with rhinosinusitis and fulfilled the selection criteria were assessed as for the symptom score and VAS and the measurement of angulation of nasal septum was performed through a coronal view of CT paranasal sinuses in bone window setting at osteomeatal complex level.

    Results: The result obtained from one-way ANOVA test revealed a significant association between category of severity of septal angulation and the symptom score of rhinosinusitis (p=0.025). In addition, the result obtained from one-way ANOVA test also revealed a significant association between category of severity of septal angulation and the VAS of rhinosinusitis (p<0.05).

    Conclusion: Severity of nasal septum angulation may be significantly associated with severity of rhinosinusitis based on symptom score and VAS. These findings could be used in tailored management of patient with rhinosinusitis especially during functional endoscopic sinus surgery.

    Matched MeSH terms: Tomography, X-Ray Computed
  3. Fulltext Narrowband Array Processing Beamforming Technique for Electrical Impedance Tomography
    Chitturi V, Farrukh N
    J Electr Bioimpedance, 2019 Jan;10(1):96-102.
    PMID: 33584889 DOI: 10.2478/joeb-2019-0014
    Electrical impedance tomography (EIT) has a large potential as a two dimensional imaging technique and is gaining attention among researchers across various fields of engineering. Beamforming techniques stem from the array signal processing field and is used for spatial filtering of array data to evaluate the location of objects. In this work the circular electrodes are treated as an array of sensors and beamforming technique is used to localize the object(s) in an electrical field. The conductivity distributions within a test tank is obtained by an EIT system in terms of electrode voltages. These voltages are then interpolated using elliptic partial differential equations. Finally, a narrowband beamformer detects the peak in the output response signal to localize the test object(s). Test results show that the beamforming technique can be used as a secondary method that may provide complementary information about accurate position of the test object(s) using an eight electrode EIT system. This method could possibly open new avenues for spatial EIT data filtering techniques with an understanding that the inverse problem is more likely considered here as a source localization algorithm instead as an image reconstruction algorithm.
    Matched MeSH terms: Tomography, X-Ray Computed
  4. Surgical management of a rare case of inverted intranasal mesiodens
    Mathew M, Sasikumar P, Vivek VJ, Kala R
    BMJ Case Rep, 2020 Oct 30;13(10).
    PMID: 33127709 DOI: 10.1136/bcr-2020-237982
    Matched MeSH terms: Tomography, X-Ray Computed
  5. Clinically important detection of infection as an 'incidental' finding during cancer staging using FDG-PET/CT
    Wong PS, Lau WF, Worth LJ, Thursky KA, Drummond E, Slavin MA, et al.
    Intern Med J, 2012 Feb;42(2):176-83.
    PMID: 21309995 DOI: 10.1111/j.1445-5994.2011.02450.x
    BACKGROUND:
    FDG-PET/CT is widely used in the management of a variety of malignancies with excellent overall accuracy, despite the potential for false positive results related to infection and inflammation.

    AIM:
      As cancer patients can develop clinically inapparent infections, we evaluated the prevalence and nature of incidental findings reported to be suggestive of infections that had been identified during clinical cancer staging with FDG-PET/CT.

    METHODS:
    The study involved a retrospective analysis of 60 patients managed primarily at our facility from a total of 121 cases identified as having possible infection on clinical reporting of more than 4500 cancer staging investigations performed during the calendar year of 2008.

    RESULTS:
    Occult infections were uncommon overall (≤1%), but most often because of pneumonia (31.6%), upper respiratory tract infections (21.1%) or wound infections (15.8%). Abnormal scans contributed to patients' management in 52.7% of cases. Two out of 13 patients whose scan abnormalities were not investigated further had worsening changes on repeated scan and one of these patients had clinical deterioration.

    CONCLUSIONS:
    In patients with FDG-PET/CT scans suggestive of infection and in whom a final diagnosis could be reached, the positive predictive value for FDG-PET/CT scans was 89% suggesting that abnormal scans indicative of infection should be investigated further in this population.
    Matched MeSH terms: Tomography, X-Ray Computed*; Positron-Emission Tomography*
  6. Fulltext A large mesenteric lipoma: an uncommon etiology of small bowel obstruction
    Vrshni Menaka R Siva Nathan, Mahedzan Mat Rabi
    Malaysian Journal of Medicine and Health Sciences, 2020;16(3):319-321.
    MyJurnal
    Fat density lesions or masses arising from the mesentery are best imaged in Computed Tomography or Magnetic Res- onance Imaging scans. This a case of a 75 year old man who presented with intestinal obstructive symptoms. Urgent computed tomography scan was carried out which revealed a large mesenteric lipoma compressing the small bowel at the level of the jejunal loops. Small bowel obstruction can be due to intrinsic, extrinsic and intraluminal causes. Mesenteric lipomas are uncommon, thus torsion or twisting of the mesenteric lipoma causing intestinal obstruction is exceptionally rare.
    Matched MeSH terms: Tomography
  7. Fulltext CT findings of congenital neonatal pyriform aperture stenosis
    Sidek HAB, Teh YG, Tangaperumal A, Zaki FM, Kew TY
    Oxf Med Case Reports, 2021 May;2021(5):omab018.
    PMID: 34055355 DOI: 10.1093/omcr/omab018
    Congenital neonatal pyriform aperture stenosis (CNPAS) is a rare but potentially lethal condition that causes respiratory distress. The characteristic narrowing of the pyriform aperture along with other associated craniofacial dysmorphism is diagnosed using cross-sectional imaging such as computed tomography (CT) and magnetic resonance imaging. CT scan is the imaging of choice for confirming and characterizing CNPAS. Infants are obligate nasal breathers in the first 5 months of life. Hence, a high degree of clinical suspicion, prompt imaging diagnosis and adequate respiratory support is critical to help reduce the morbidity of this condition.
    Matched MeSH terms: Tomography, X-Ray Computed
  8. Correlation and accuracy of contrast-enhanced computed tomography in assessing depth of invasion of oral tongue carcinoma
    Chin SY, Kadir K, Ibrahim N, Rahmat K
    Int J Oral Maxillofac Surg, 2021 Jun;50(6):718-724.
    PMID: 33162298 DOI: 10.1016/j.ijom.2020.09.025
    The aim of this study was to evaluate the correlation and accuracy of depth of invasion (DOI) measurement from preoperative contrast-enhanced computed tomography (CECT) scans in comparison to histopathological examination (HPE) in oral tongue squamous cell carcinoma (OTSCC). Preoperative CT scans of 18 OTSCC patients were reviewed retrospectively by a single observer to measure the DOI on axial and coronal sections; these were then compared to the HPE report. Mean DOI was compared between CECT and HPE using repeated measures ANOVA. The strength of correlation of CT-derived tumour depth was determined using the intra-class correlation coefficient (ICC) followed by assessment of accuracy by Bland-Altman plot. In general, the measurement of DOI was smaller on CECT, with a mean difference of 0.743mm on axial CT and 1.106mm on coronal CT. Regarding the correlation between CECT and HPE tumour depths, ICC was 0.956 for axial CT and 0.965 for coronal CT. Bland-Altman analysis showed that DOI from CECT and histopathological depth were in agreement with each other. In conclusion, there was excellent correlation and accurate measurement of DOI from CECT.
    Matched MeSH terms: Tomography, X-Ray Computed
  9. Fulltext Nasal airflow of patient with septal deviation and allergy rhinitis
    Lim ZF, Rajendran P, Musa MY, Lee CF
    Vis Comput Ind Biomed Art, 2021 May 20;4(1):14.
    PMID: 34014417 DOI: 10.1186/s42492-021-00080-2
    A numerical simulation of a patient's nasal airflow was developed via computational fluid dynamics. Accordingly, computerized tomography scans of a patient with septal deviation and allergic rhinitis were obtained. The three-dimensional (3D) nasal model was designed using InVesalius 3.0, which was then imported to (computer aided 3D interactive application) CATIA V5 for modification, and finally to analysis system (ANSYS) flow oriented logistics upgrade for enterprise networks (FLUENT) to obtain the numerical solution. The velocity contours of the cross-sectional area were analyzed on four main surfaces: the vestibule, nasal valve, middle turbinate, and nasopharynx. The pressure and velocity characteristics were assessed at both laminar and turbulent mass flow rates for both the standardized and the patient's model nasal cavity. The developed model of the patient is approximately half the size of the standardized model; hence, its velocity was approximately two times more than that of the standardized model.
    Matched MeSH terms: Tomography
  10. Radiation dose reduction in thoracic and abdomen-pelvic CT using tube current modulation: a phantom study
    Sabarudin A, Mustafa Z, Nassir KM, Hamid HA, Sun Z
    J Appl Clin Med Phys, 2015 Jan;16(1):319-328.
    PMID: 28297258 DOI: 10.1120/jacmp.v16i1.5135
    This phantom study was designed to compare the radiation dose in thoracic and abdomen-pelvic CT scans with and without use of tube current modulation (TCM). Effective dose (ED) and size-specific dose estimation (SSDE) were calculated with the absorbed doses measured at selective radiosensitive organs using a thermoluminescence dosimeter-100 (TLD-100). When compared to protocols without TCM, the ED and SSDE were reduced significantly with use of TCM for both the thoracic and abdomen-pelvic CT. With use of TCM, the ED was 6.50±0.29 mSv for thoracic and 6.01±0.20 mSv for the abdomen-pelvic CT protocols. However without use of TCM, the ED was 20.07±0.24 mSv and 17.30±0.41 mSv for the thoracic and abdomen-pelvic CT protocols, respectively. The corresponding SSDE was 10.18±0.48 mGy and 11.96±0.27 mGy for the thoracic and abdomen-pelvic CT protocols with TCM, and 31.56±0.43 mGy and 33.23±0.05 mGy for thoracic and abdomen-pelvic CT protocols without TCM, respectively. The highest absorbed dose was measured at the breast with 8.58±0.12 mGy in the TCM protocols and 51.52±14.72 mGy in the protocols without TCM during thoracic CT. In the abdomen-pelvic CT, the absorbed dose was highest at the skin with 9.30±1.28 mGy and 29.99±2.23 mGy in protocols with and without use of TCM, respectively. In conclusion, the TCM technique results in significant dose reduction; thus it is to be highly recommended in routine thoracic and abdomen-pelvic CT. PACS numbers: 87.57.Q-, 87.57.qp, 87.53.Bn.
    Matched MeSH terms: Tomography, X-Ray Computed
  11. An insight into the role of Artificial Intelligence in the early diagnosis of Alzheimer's disease
    Verma RK, Pandey M, Chawla P, Choudhury H, Mayuren J, Bhattamisra SK, et al.
    CNS Neurol Disord Drug Targets, 2021 May 11.
    PMID: 33982657 DOI: 10.2174/1871527320666210512014505
    BACKGROUND: The complication of Alzheimer's disease (AD) has made the development of its therapeutic a challenging task. Even after decades of research, we have achieved no more than a few years of symptomatic relief. The inability to diagnose the disease early is the foremost hurdle behind its treatment. Several studies have aimed to identify potential biomarkers that can be detected in body fluids (CSF, blood, urine, etc) or assessed by neuroimaging (i.e., PET and MRI). However, the clinical implementation of these biomarkers is incomplete as they cannot be validated.

    METHOD: To overcome the limitation, the use of artificial intelligence along with technical tools has been extensively investigated for AD diagnosis. For developing a promising artificial intelligence strategy that can diagnose AD early, it is critical to supervise neuropsychological outcomes and imaging-based readouts with a proper clinical review.

    CONCLUSION: Profound knowledge, a large data pool, and detailed investigations are required for the successful implementation of this tool. This review will enlighten various aspects of early diagnosis of AD using artificial intelligence.

    Matched MeSH terms: Positron-Emission Tomography
  12. Fulltext Comparison of Low-Pass Filters for SPECT Imaging
    Sayed IS, Ismail SS
    Int J Biomed Imaging, 2020;2020:9239753.
    PMID: 32308670 DOI: 10.1155/2020/9239753
    In single photon emission computed tomography (SPECT) imaging, the choice of a suitable filter and its parameters for noise reduction purposes is a big challenge. Adverse effects on image quality arise if an improper filter is selected. Filtered back projection (FBP) is the most popular technique for image reconstruction in SPECT. With this technique, different types of reconstruction filters are used, such as the Butterworth and the Hamming. In this study, the effects on the quality of reconstructed images of the Butterworth filter were compared with the ones of the Hamming filter. A Philips ADAC forte gamma camera was used. A low-energy, high-resolution collimator was installed on the gamma camera. SPECT data were acquired by scanning a phantom with an insert composed of hot and cold regions. A Technetium-99m radioactive solution was homogenously mixed into the phantom. Furthermore, a symmetrical energy window (20%) centered at 140 keV was adjusted. Images were reconstructed by the FBP method. Various cutoff frequency values, namely, 0.35, 0.40, 0.45, and 0.50 cycles/cm, were selected for both filters, whereas for the Butterworth filter, the order was set at 7. Images of hot and cold regions were analyzed in terms of detectability, contrast, and signal-to-noise ratio (SNR). The findings of our study indicate that the Butterworth filter was able to expose more hot and cold regions in reconstructed images. In addition, higher contrast values were recorded, as compared to the Hamming filter. However, with the Butterworth filter, the decrease in SNR for both types of regions with the increase in cutoff frequency as compared to the Hamming filter was obtained. Overall, the Butterworth filter under investigation provided superior results than the Hamming filter. Effects of both filters on the quality of hot and cold region images varied with the change in cutoff frequency.
    Matched MeSH terms: Tomography, Emission-Computed, Single-Photon
  13. Sickle Cell Maculopathy: Prevalence, Associations and Impact on Visual Acuity
    Sahak H, Saqalain M, Lott PW, McKibbin M
    Ophthalmologica, 2021;244(2):159-164.
    PMID: 33120391 DOI: 10.1159/000512636
    AIMS: To investigate the prevalence of sickle cell maculopathy (SCM), and associations with age, sex, genotype, proliferative sickle cell retinopathy (PSR) stage, and the impact on visual acuity.

    METHODS: Age, sex, and visual acuity were recorded and spectral domain OCT and ultra-wide-field images of the macula and retina were reviewed in a consecutive series of 74 adults with sickle cell disease.

    RESULTS: The median age was 37 years (range 19-73 years) and 36 cases (48.6%) were male. SCM was present in at least 1 eye of 40 cases (54.1%) or in 67 of all eyes (42.3%). SCM prevalence was 54.8%, 62.5%, and 25% for the HbSS, HbSC, and HbS/BThal or other genotypes, respectively. SCM was observed in 41 (39.4%) of the eyes with PSR stages 0, 1, and 2, and in 21 (51.2%) of the eyes with PSR stages 3, 4, and 5, respectively. Mild visual impairment or worse was present in 3 eyes (4.8%) with SCM but this was secondary to other pathology.

    CONCLUSION: SCM is a frequent finding in the eyes of adults with sickle cell disease. The prevalence is similar for the HbSS and HbSC genotypes and is not related to the PSR stage. High-contrast distance visual acuity is typically preserved.

    Matched MeSH terms: Tomography, Optical Coherence
  14. Fulltext Azygos continuation of the inferior vena cava in carcinoma of oesophagus.
    Mubarak, M.Y.
    International Medical Journal Malaysia, 2008;7(2):57-61.
    MyJurnal
    The azygos system enlarges in cases of obstruction to the superior vena cava or inferior vena cava and result in increase blood flow through the system. Azygos continuation of the inferior vena cava is usually congenital and asymptomatic. The azygos vein is the sole drainage of the blood from the lower half of the body to the heart. It is crucial to identify the anomaly as it might involve in the surgical planning of tumours in the thorax or abdomen. Computed Tomography is a non-invasive technique and provide important information about the tumour and the vascular anomaly.
    Matched MeSH terms: Tomography
  15. Fulltext Growth of Hepatocellular Carcinoma into the Right Atrium with Associated Pulmonary Tumour Emboli
    Amran, A.R., Ranganathan, S.
    International Medical Journal Malaysia, 2006;5(1):1-5.
    MyJurnal
    Hepatocellular carcinoma (HCC) presenting with right atrial metastases and pulmonary tumour embolism is rare . Intracavitary cardiac metastasis is uncommon and metastasis to the right atrium is even less common. The majority of such cases are believed to be due to advanced HCC such as Stage III or IV, in which the progression rate is high, and in infiltrative HCC it tends to be associated with vascular invasion. The diagnosis of pulmonary intravascular tumour emboli is difficult to establish both clinically and with conventional radiographic studies. We report a case hepatocellular carcinoma associated with tumour thrombus in the inferior vena cava (IVC), right atrium and pulmonary tumour embolism detected with multidetector helical computerized tomography (MDHCT).
    Matched MeSH terms: Tomography, Spiral Computed
  16. Fulltext An Accidental Finding of Pulmonary Sequestration in an Adult
    Amran, A.R.
    International Medical Journal Malaysia, 2006;5(1):1-6.
    MyJurnal
    Pulmonary sequestration is defined as a segment of ç separated from the tracheobronchial tree and receiving its blood supply from a systemic artery rather than a pulmonary arterial branch. Classically, it has been described in two forms: (1) intralobar sequestration (ILS), in which the sequestrated part of lung lies within normal pulmonary visceral pleura, and (2) extralobar sequestration (ELS), in which the abnormal segment of lung is completely separate and enclosed in its own pleural investment. The term sequestration was coined by Pryce in 1946 to describe a disconnected bronchopulmonary mass or cyst with an anomalous systemic artery. Since this original description, terminology has become confusing as investigator has recognized many variants of sequestration not strictly meeting the original description. The spectrum now recognized as a continuum, with normal vessels supplying abnormal lung at one end and abnormal vessels supplying normal lung at the other end. Recently, we incidentally found an asymptomatic, intralobar pulmonary sequestration during CT pneumocolon.
    Matched MeSH terms: Tomography, X-Ray Computed
  17. Fulltext The efficacy of pre-operative laparoscopy in the staging for gastric cancer
    Kandasami P
    International e-Journal of Science, Medicine & Education, 2012;6(Suppl 1):103-105.
    MyJurnal
    The only potential curative therapy for gastric cancer is the resection of both the tumor and the regional lymph nodes at the early stage of the disease. The majority of patients with gastric cancer in Malaysia have an advanced disease at initial diagnosis, and curative surgery is possible in less than 20% of operated cases. Acurate preoperative staging is crucial in determining the most suitable therapy and avoiding unnecessary attempts at curative surgery. While computed tomography remains as the most widely used imaging modality for gastric cancer staging, its ability to detect local invasion, peritoneal and liver metastases is limited. In the recent years laparoscopy has become an important component in the staging algorithm of gastric cancer. The aim of this review is to evaluate the efficacy of routine preoperative laparoscopic staging in the management of gastric cancer, and in particular describe the Malaysian experience.
    Matched MeSH terms: Tomography, X-Ray Computed
  18. Fulltext Dysphagia caused by an aberrant right subclavian artery
    Radhiana, H., Ahmad Razali, M.R., Wan Ishlah, W.L.
    International Medical Journal Malaysia, 2011;10(1):43-45.
    MyJurnal
    An aberrant right subclavian artery is the commonest aortic arch anomaly. Majority of them were asymptomatic. An aberrant subclavian artery is a rare cause of dysphagia in adults. This condition is also known as dysphagia lusoria. We report a case of dysphagia in a 49-year-old woman from an aberrant right subclavian artery. Diagnosis of her condition was made with barium swallow and MDCT (multidetector computed tomography) scan. She was managed conservatively.
    Matched MeSH terms: Multidetector Computed Tomography
  19. Fulltext Tuberous sclerosis with pulmonary lymphangioleiomyomatosis and renal angiomyolipomas
    Hui Min Chong, Shien Yee Ng
    International e-Journal of Science, Medicine & Education, 2014;8(2):30-34.
    MyJurnal
    The case report describes the presentation of a 19-year old female with tuberous sclerosis who presented with progressive dyspnoea over 2 days.
    Chest radiograph revealed bilateral pneumothorax. Computed tomography showed features of pulmonary lymphangioleiomyomatosis and bilateral renal angiomyolipomas. The coexistence of both conditions may cause devastating morbidity and mortality.
    Matched MeSH terms: Tomography, X-Ray Computed
  20. Fulltext Thoracic aortic aneurysm presenting as vocal cord paralysis
    Norly, S., Noorizan, Y., Ros’aini, P.
    International Medical Journal Malaysia, 2013;12(1):67-68.
    MyJurnal
    We present a case of 80-year-old man with two-year history of hoarseness of voice secondary to left vocal cord paralysis. CT scanning revealed a saccular thoracic aneurysm compressing the left recurrent laryngeal nerve. A review of literature on Ortner's or cardiovocal syndrome is presented.
    Matched MeSH terms: Tomography, X-Ray Computed
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