Displaying publications 41 - 51 of 51 in total

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  1. Anboo S, Lau SY, Kansedo J, Yap PS, Hadibarata T, Jeevanandam J, et al.
    Biotechnol Bioeng, 2022 Oct;119(10):2609-2638.
    PMID: 35851660 DOI: 10.1002/bit.28185
    Over the past decade, nanotechnology has been developed and employed across various entities. Among the numerous nanostructured material types, enzyme-incorporated nanomaterials have shown great potential in various fields, as an alternative to biologically derived as well as synthetically developed hybrid structures. The mechanism of incorporating enzyme onto a nanostructure depends on several factors including the method of immobilization, type of nanomaterial, as well as operational and environmental conditions. The prospects of enzyme-incorporated nanomaterials have shown promising results across various applications, such as biocatalysts, biosensors, drug therapy, and wastewater treatment. This is due to their excellent ability to exhibit chemical and physical properties such as high surface-to-volume ratio, recovery and/or reusability rates, sensitivity, response scale, and stable catalytic activity across wide operating conditions. In this review, the evolution of enzyme-incorporated nanomaterials along with their impact on our society due to its state-of-the-art properties, and its significance across different industrial applications are discussed. In addition, the weakness and future prospects of enzyme-incorporated nanomaterials were also discussed to guide scientists for futuristic research and development in this field.
  2. Sukmono Y, Hadibarata T, Kristanti RA, Singh A, Al Farraj DA, Elshikh MS
    J Contam Hydrol, 2024 Nov;267:104440.
    PMID: 39396457 DOI: 10.1016/j.jconhyd.2024.104440
    Indonesia generates approximately 7.8 million tons of plastic waste annually, which 4.9 million tons is mismanaged. Presently, there is significant concern on microplastics (MPs) pollution in aquatic environment. The research on the prevalence of MPs in river systems are comparatively lower than the studies conducted on marine systems. The primary goal of this research was to look into the prevalence of MPs in the river water of Mahakam of Tenggarong City, Indonesia. To adequately represent this area, a meticulous selection method was used to find five separate sampling locations, with two stations at each location, positioned 200 m apart on opposite sides of the river. According to the study's findings, MPs has been observed in the range of 19.2 ± 1.8 to 58.5 ± 3.5 particles/l. Based on the MPs type, fragments (43.4 %) were the most common type of MPs found in water samples. Furthermore, 44.6 % of the MPs had size smaller than 1000 μm. The prevalent hues observed in the water samples were transparent and black, composing 75.6 % of overall formation. The determination of microplastic polymers employed Attenuated Total Reflection-Fourier Transform Infrared (ATR-FTIR) spectroscopy, revealing the presence of various type, such as polyethylene (PE) and polypropylene (PP).
  3. Hadibarata T, Teh ZC, Rubiyatno, Zubir MM, Khudhair AB, Yusoff AR, et al.
    Bioprocess Biosyst Eng, 2013 Oct;36(10):1455-61.
    PMID: 23334282 DOI: 10.1007/s00449-013-0884-8
    The use of biomaterials or microorganisms in PAHs degradation had presented an eye-catching performance. Pleurotus eryngii is a white rot fungus, which is easily isolated from the decayed woods in the tropical rain forest, used to determine the capability to utilize naphthalene, a two-ring polycyclic aromatic hydrocarbon as source of carbon and energy. In the meantime, biotransformation of naphthalene to intermediates and other by-products during degradation was investigated in this study. Pleurotus eryngii had been incubated in liquid medium formulated with naphthalene for 14 days. The presence of metabolites of naphthalene suggests that Pleurotus eryngii begin the ring cleavage by dioxygenation on C1 and C4 position to give 1,4-naphthaquinone. 1,4-Naphthaquinone was further degraded to benzoic acid, where the proposed terepthalic acid is absent in the cultured extract. Further degradation of benzoic acid by Pleurotus eryngii shows the existence of catechol as a result of the combination of decarboxylation and hydroxylation process. Unfortunately, phthalic acid was not detected in this study. Several enzymes, including manganese peroxidase, lignin peroxidase, laccase, 1,2-dioxygenase and 2,3-dioxygenase are enzymes responsible for naphthalene degradation. Reduction of naphthalene and the presence of metabolites in liquid medium showed the ability of Pleurotus eryngii to utilize naphthalene as carbon source instead of a limited glucose amount.
  4. Al Farraj DA, Hadibarata T, Yuniarto A, Syafiuddin A, Surtikanti HK, Elshikh MS, et al.
    Bioprocess Biosyst Eng, 2019 Jun;42(6):963-969.
    PMID: 30888502 DOI: 10.1007/s00449-019-02096-8
    Polycyclic aromatics hydrocarbons (PAHs) are ubiquitous and toxic pollutants that are dangerous to humans and living organism in aquatic environment. Normally, PAHs has lower molecular weight such as phenanthrene and naphthalene that are easy and efficient to degrade, but high-molecular-weight PAHs such as chrysene and pyrene are difficult to be biodegraded by common microorganism. This study investigated the isolation and characterization of a potential halophilic bacterium capable of utilizing two high-molecular-weight PAHs. At the end of the experiment (25-30 days of incubation), bacterial counts have reached a maximum level (over 40 × 1016 CFU/mL). The highest biodegradation rate of 77% of chrysene in 20 days and 92% of pyrene in 25 days was obtained at pH 7, temperature 25 °C, agitation of 150 rpm and Tween 80 surfactant showing to be the most impressive parameters for HMWPAHs biodegradation in this research. The metabolism of initial compounds revealed that Hortaea sp. B15 utilized pyrene to form phthalic acid while chrysene was metabolized to form 1-hydroxy-2-naphthoic acid. The result showed that Hortaea sp. B15 can be promoted for the study of in situ biodegradation of high molecular weight PAH.
  5. Choong WS, Hadibarata T, Yuniarto A, Tang KHD, Abdullah F, Syafrudin M, et al.
    Mar Pollut Bull, 2021 Nov;172:112880.
    PMID: 34428625 DOI: 10.1016/j.marpolbul.2021.112880
    The Baram River is one of the largest rivers in Sarawak, where many large industries, such as plywood, sawmills, shipyards, interisland ports, and other wood-based industries are located along the river. Microplastic contamination has become a widespread and growing concern worldwide because of the small sizes of microplastics and their presence in seafood such as fish, squid, scallop, crabs, shrimp, and mussels. In this study, microplastics were found in all sampling stations. Out of the 4017 microplastics found in the water and sediment, microplastics fragment accounted for 67.8% of total microplastics, followed by fiber, film, pellet, and foam. Five microplastic polymer types were detected by ATR-FTIR, including polyethylene (PE), polyester (PET) fibers, silicon polymer, nitrile, and polystyrene (PS). The most common microplastics size range in Baram River was 0.3-1 mm, with blue as the highly abundant color.
  6. Ismanto A, Hadibarata T, Widada S, Indrayanti E, Ismunarti DH, Safinatunnajah N, et al.
    Bioprocess Biosyst Eng, 2023 Mar;46(3):467-482.
    PMID: 36520279 DOI: 10.1007/s00449-022-02826-5
    Groundwater is defined as water that exists underground in voids or gaps in sediments and is extracted for human consumption from aquifers. It is critical to our daily lives because it contributes to the sustainability of our natural ecosystem while also providing economic benefits. Heavy metals are metallic compounds with a relatively high atomic weight and density compared to water. In Malaysia, heavy metal contamination of groundwater has become a concern due to rapid population growth, economic development, and a lack of environmental awareness. Environmental factors or their behaviors, such as density, viscosity, or volume, affect the distribution and transportation of heavy metals. The article discusses the difficulties created by the presence of heavy metals in groundwater supplies and the resulting health problems. Additionally, remediation methods are discussed for managing contaminated water to preserve the ecological environment for current and future generations, as well as their advantages and disadvantages.
  7. Hadibarata T, Zubir MM, Rubiyatno, Chuang TZ, Yusoff AR, Salim MR, et al.
    Folia Microbiol (Praha), 2013 Sep;58(5):385-91.
    PMID: 23307571 DOI: 10.1007/s12223-013-0221-2
    Characterization of anthracene metabolites produced by Armillaria sp. F022 was performed in the enzymatic system. The fungal culture was conducted in 100-mL Erlenmeyer flask containing mineral salt broth medium (20 mL) and incubated at 120 rpm for 5-30 days. The culture broth was then centrifuged at 10,000 rpm for 45 min to obtain the extract. Additionally, the effect of glucose consumption, laccase activity, and biomass production in degradation of anthracene were also investigated. Approximately, 92 % of the initial concentration of anthracene was degraded within 30 days of incubation. Dynamic pattern of the biomass production was affected the laccase activity during the experiment. The biomass of the fungus increased with the increasing of laccase activity. The isolation and characterization of four metabolites indicated that the structure of anthracene was transformed by Armillaria sp. F022 in two routes. First, anthracene was oxidized to form anthraquinone, benzoic acid, and second, converted into other products, 2-hydroxy-3-naphthoic acid and coumarin. Gas chromatography-mass spectrometry analysis also revealed that the molecular structure of anthracene was transformed by the action of the enzyme, generating a series of intermediate compounds such as anthraquinone by ring-cleavage reactions. The ligninolytic enzymes expecially free extracellular laccase played an important role in the transformation of anthracene during degradation period.
  8. Ismanto A, Hadibarata T, Kristanti RA, Sugianto DN, Widada S, Atmodjo W, et al.
    Mar Pollut Bull, 2023 Nov;196:115563.
    PMID: 37797535 DOI: 10.1016/j.marpolbul.2023.115563
    This study aimed to address the pressing issue of plastic pollution in aquatic ecosystems by assessing the prevalence and distribution of microplastics (MPs) in water and riverbank sediments of the Pekalongan River, a vital water source in Indonesia. From the present findings, MP concentrations in water ranged from 45.2 to 99.1 particles/L, while sediment concentrations ranged from 0.77 to 1.01 particles/g. This study revealed that fragment and film MPs constituted 30.1 % and 25.4 % of the total, respectively, with MPs measuring <1 mm and constituting 51.4 % of the total. Colored MPs, particularly blue and black MPs, accounted for 34 % of the total. The primary polymer components, as determined via Fourier transform infrared spectroscopy, were identified as polystyrene, polyester, and polyamide. In response to the escalating plastic waste crisis caused by single-use plastics, Pekalongan's local government implemented refuse segregation and recycling programs as part of its efforts to transition toward zero-waste practices.
  9. Andreas, Hadibarata T, Sathishkumar P, Prasetia H, Hikmat, Pusfitasari ED, et al.
    Chemosphere, 2021 Aug;276:130185.
    PMID: 33743420 DOI: 10.1016/j.chemosphere.2021.130185
    Indonesia is the second-largest contributor of microplastics (MPs) pollution in the marine ecosystem. Most MPs pollution-related studies in Indonesia focus on seawater, sediment, with less information found on the commercially important fish species used for human consumption. Skipjack Tuna (Euthynnus affinis) is one of the major exporting fishery commodities from Indonesia. This exploratory study aimed to determine MPs presence in the digestive tract of Skipjack Tuna from the Southern Coast of Java, Indonesia. The fish samples were collected from five different fish traditional auction market along the Southern Coast of Java, Indonesia, namely Pangandaran, Pamayang Sari, Ciletuh, Santolo, and Palabuhan Ratu. The gastrointestinal tract of Skipjack tuna was pretreated using alkaline destruction and filtered. The presence of MPs in the treated samples was visually identified using an optical microscope, while Polybrominated diphenyl ethers (PBDEs) contaminants were analyzed using Gas Chromatography-Mass Spectrometry (GC-MS). A total of 19 suspected MPs particles were found in the form of filament (84%), angular (11%), and round (5%). This result would provide a better indication of the MPs contamination in marine life species in the Southern Coast of Java, Indonesia, as useful information for marine environmental monitoring program in the future.
  10. Ismanto A, Hadibarata T, Sugianto DN, Zainuri M, Kristanti RA, Wisha UJ, et al.
    Mar Pollut Bull, 2023 Nov;196:115677.
    PMID: 37862842 DOI: 10.1016/j.marpolbul.2023.115677
    The main aim of this study was to assess the presence of microplastics in the water and sediments of the Surakarta city river basin in Indonesia. In order to accurately reflect the river basin, a deliberate selection process was employed to choose three separate sampling locations and twelve sampling points. The results of the study revealed that fragments and fibers were the primary types of microplastics seen in both water and sediment samples. Furthermore, a considerable percentage of microplastics, comprising 53.8 % of the total, had dimensions below 1 mm. Moreover, the prevailing hues identified in the water samples were blue and black, comprising 45.1 % of the overall composition. In contrast, same color categories accounted for 23.3 % of the microplastics found in the soil samples. The analysis of microplastic polymers was carried out utilizing ATR-FTIR spectroscopy, which yielded the identification of various types including polystyrene, silicone polymer, polyester, and polyamide.
  11. Anindita MA, Ismanto A, Zainuri M, Hadibarata T, Kunarso K, Maslukah L, et al.
    Environ Monit Assess, 2024 Aug 23;196(9):832.
    PMID: 39177841 DOI: 10.1007/s10661-024-13016-z
    This research aims to understand the extent of microplastic contamination in Pekalongan waters, Central Java, and its potential impact on fishing grounds, aligning with Indonesia's National Action Plan for Handling Marine Debris 2018-2025. The study employs a 2D hydrodynamics modelling approach with Mike 21 Software to map the spatial distribution of microplastic movement concerning fishing areas during the west and east monsoon seasons. The results showed that microplastic particles follow tidal currents in Pekalongan waters, with their movement influenced by factors such as current, wind, and tidal conditions. The trajectory of microplastics entering fishing ground areas poses potential contamination risk for fish caught by fishermen, threatening the health of marine ecosystems and the stability of their structure and function.
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