MyMedR

John Desmond Gimlette: "one of God's own"

Fleming PR

J Med Biogr, 1998 Nov;6(4):222-6.

Matched MeSH terms: Tropical Medicine/history*

Fulltext Pneumonia in the tropics: Report from the Task Force on tropical diseases by the World Federation of Societies of Intensive and Critical Care Medicine

Nor MBM, Richards GA, McGloughlin S, Amin PR, Council of the World Federation of Societies of Intensive and Critical Care Medicine

J Crit Care, 2017 12;42:360-365.

PMID: 29129538 DOI: 10.1016/j.jcrc.2017.11.004

The aetiology of community acquired pneumonia varies according to the region in which it is acquired. This review discusses those causes of CAP that occur in the tropics and might not be readily recognizable when transplanted to other sites. Various forms of pneumonia including the viral causes such as influenza (seasonal and avian varieties), the coronaviruses and the Hantavirus as well as bacterial causes, specifically the pneumonic form of Yersinia pestis and melioidosis are discussed.

Matched MeSH terms: Tropical Medicine

Intensive care in severe malaria: Report from the task force on tropical diseases by the World Federation of Societies of Intensive and Critical Care Medicine

Karnad DR, Nor MBM, Richards GA, Baker T, Amin P, Council of the World Federation of Societies of Intensive and Critical Care Medicine

J Crit Care, 2018 Feb;43:356-360.

PMID: 29132978 DOI: 10.1016/j.jcrc.2017.11.007

Severe malaria is common in tropical countries in Africa, Asia, Oceania and South and Central America. It may also occur in travelers returning from endemic areas. Plasmodium falciparum accounts for most cases, although P vivax is increasingly found to cause severe malaria in Asia. Cerebral malaria is common in children in Africa, manifests as coma and seizures, and has a high morbidity and mortality. In other regions, adults may also develop cerebral malaria but neurological sequelae in survivors are rare. Acute kidney injury, liver dysfunction, thrombocytopenia, disseminated intravascular coagulopathy (DIC) and acute respiratory distress syndrome (ARDS) are also common in severe malaria. Metabolic abnormalities include hypoglycemia, hyponatremia and lactic acidosis. Bacterial infection may coexist in patients presenting with shock or ARDS and this along with a high parasite load has a high mortality. Intravenous artesunate has replaced quinine as the antimalarial agent of choice. Critical care management as per severe sepsis is also applicable to severe malaria. Aggressive fluid boluses may not be appropriate in children. Blood transfusions may be required and treatment of seizures and raised intracranial pressure is important in cerebral malaria in children. Mortality in severe disease ranges from 8 to 30% despite treatment.

Matched MeSH terms: Tropical Medicine*

Sepsis in tropical regions: Report from the task force on tropical diseases by the World Federation of Societies of Intensive and Critical Care Medicine

McGloughlin S, Richards GA, Nor MBM, Prayag S, Baker T, Amin P

J Crit Care, 2018 08;46:115-118.

PMID: 29310974 DOI: 10.1016/j.jcrc.2017.12.018

Sepsis and septic shock in the tropics are caused by a wide array of organisms. These infections are encountered mainly in low and middle-income countries (LMIC) where a lack of infrastructure and medical facilities contribute to the high morbidity and mortality. Published sepsis guidelines are based on studies primarily performed in high income countries and as such recommendations may or may not be relevant to practice in the tropics. Failure to adhere to guidelines, particularly among non-intensive care specialists even in high-income countries, is an area of concern for sepsis management. Additionally, inappropriate use of antimicrobials has led to significant antimicrobial resistance. Access to rapid, low-cost, and accurate diagnostic tests is critical in countries where tropical diseases are prevalent to facilitate early diagnosis and treatment. Implementation of performance improvement programs may improve outcomes for patients with sepsis and the addition of resuscitation and treatment bundles may further reduce mortality. Associated co-morbidities such as malnutrition and HIV influence outcomes and must be considered.

Matched MeSH terms: Tropical Medicine/organization & administration

Tropical medicine and industrial development

Waddy BB

J Trop Med Hyg, 1974 Apr;77(4):s:19-21.

PMID: 4841357

Matched MeSH terms: Tropical Medicine*

Tropical myositis in Malaya

ROBIN GC

J Trop Med Hyg, 1961 Nov;64:288-91.

PMID: 14492859

Matched MeSH terms: Tropical Medicine*

Medical problems of the operational infantry soldier in Malaya

ARCHER TC

J R Army Med Corps, 1958 Jan;104(1):1-13.

PMID: 13502878

Matched MeSH terms: Tropical Medicine*

Nutrition in adverse environments, 3. The metabolic effects of a restricted food intake on men working in a tropical environment

Crowdy JP, Consolazio CF, Forbes AL, Haisman MF, Worsley DE

Hum Nutr Appl Nutr, 1982 Oct;36(5):325-44.

PMID: 7141879

As part of a research programme concerned with the need to lighten the load carried by soldiers engaged in long foot patrols, a field experiment was undertaken in West Malaysia. For 12 d a group of 15 men consumed 7.4 MJ/d (1770 kcal/d) whilst a control group of 14 men ate 12.9 MJ/d (3080 kcal/d); both groups expended on average about 15.8 MJ/d (3770 kcal/d). The low-energy group incurred an energy deficit of 98 MJ (23 410 kcal) with a weight loss of 3.9 kg, whereas corresponding figures for the control group were 37 MJ (8840 kcal) and 2.4 kg. Before, during and after the energy deprivation phase, assessment was made of work capacity (estimated VO2 max), vigilance and military skills but no difference was found between the groups.

Matched MeSH terms: Tropical Medicine/trends*

Fulltext Social sciences research in neglected tropical diseases 1: the ongoing neglect in the neglected tropical diseases

Allotey P, Reidpath DD, Pokhrel S

Health Res Policy Syst, 2010 Oct 21;8:32.

PMID: 20961461 DOI: 10.1186/1478-4505-8-32

Centuries of scientific advances and developments in biomedical sciences have brought us a long way to understanding and managing disease processes, by reducing them to simplified cause-effect models. For most of the infectious diseases known today, we have the methods and technology to identify the causative agent, understand the mechanism by which pathology is induced and develop the treatment (drugs, vaccines, medical or surgical procedures) to cure, manage or control.Disease, however, occurs within a context of lives fraught with complexity. For any given infectious disease, who gets it, when, why, the duration, the severity, the outcome, the sequelae, are bound by a complex interplay of factors related as much to the individual as it is to the physical, social, cultural, political and economic environments. Furthermore each of these factors is in a dynamic state of change, evolving over time as they interact with each other. Simple solutions to infectious diseases are therefore rarely sustainable solutions. Sustainability would require the development of interdisciplinary sciences that allow us to acknowledge, understand and address these complexities as they occur, rather than rely solely on a form of science based on reducing the management of disease to simple paradigms.In this review we examine the current global health responses to the 'neglected' tropical diseases, which have been prioritised on the basis of an acknowledgment of the complexity of the poverty-disease cycle. However research and interventions for neglected tropical diseases, largely neglect the social and ecological contextual, factors that make these diseases persist in the target populations, continuing instead to focus on the simple biomedical interventions. We highlight the gaps in the approaches and explore the potential of enhanced interdisciplinary work in the development of long term solutions to disease control.

Matched MeSH terms: Tropical Medicine

Fulltext Cinnamon: a multifaceted medicinal plant

Rao PV, Gan SH

Evid Based Complement Alternat Med, 2014;2014:642942.

PMID: 24817901 DOI: 10.1155/2014/642942

Cinnamon (Cinnamomum zeylanicum, and Cinnamon cassia), the eternal tree of tropical medicine, belongs to the Lauraceae family. Cinnamon is one of the most important spices used daily by people all over the world. Cinnamon primarily contains vital oils and other derivatives, such as cinnamaldehyde, cinnamic acid, and cinnamate. In addition to being an antioxidant, anti-inflammatory, antidiabetic, antimicrobial, anticancer, lipid-lowering, and cardiovascular-disease-lowering compound, cinnamon has also been reported to have activities against neurological disorders, such as Parkinson's and Alzheimer's diseases. This review illustrates the pharmacological prospective of cinnamon and its use in daily life.

Matched MeSH terms: Tropical Medicine

Mosquito control with green nanopesticides: towards the One Health approach? A review of non-target effects

Benelli G, Maggi F, Pavela R, Murugan K, Govindarajan M, Vaseeharan B, et al.

Environ Sci Pollut Res Int, 2018 Apr;25(11):10184-10206.

PMID: 28755145 DOI: 10.1007/s11356-017-9752-4

The rapid spread of highly aggressive arboviruses, parasites, and bacteria along with the development of resistance in the pathogens and parasites, as well as in their arthropod vectors, represents a huge challenge in modern parasitology and tropical medicine. Eco-friendly vector control programs are crucial to fight, besides malaria, the spread of dengue, West Nile, chikungunya, and Zika virus, as well as other arboviruses such as St. Louis encephalitis and Japanese encephalitis. However, research efforts on the control of mosquito vectors are experiencing a serious lack of eco-friendly and highly effective pesticides, as well as the limited success of most biocontrol tools currently applied. Most importantly, a cooperative interface between the two disciplines is still lacking. To face this challenge, we have reviewed a wide number of promising results in the field of green-fabricated pesticides tested against mosquito vectors, outlining several examples of synergy with classic biological control tools. The non-target effects of green-fabricated nanopesticides, including acute toxicity, genotoxicity, and impact on behavioral traits of mosquito predators, have been critically discussed. In the final section, we have identified several key challenges at the interface between "green" nanotechnology and classic biological control, which deserve further research attention.

Matched MeSH terms: Tropical Medicine

Iron deficiency in the tropics

Fleming AF

Clin Haematol, 1982 Jun;11(2):365-88.

PMID: 7042157

Matched MeSH terms: Tropical Medicine*

Disease, race, and empire

Anderson W

Bull Hist Med, 1996;70(1):62-7.

PMID: 8850070

Matched MeSH terms: Tropical Medicine/history*

Where is the postcolonial history of medicine? Essay review

Anderson W

Bull Hist Med, 1998;72(3):522-30.

PMID: 9780451

Matched MeSH terms: Tropical Medicine/history*

Fulltext Yellow fever vaccination in Malaya by subcutaneous injection and multiple puncture. Haemagglutinin-inhibiting antibody responses in persons with and without pre-existing antibody

Gordon Smith CE, McMahon DA, Turner LH

Bull World Health Organ, 1963;29:75-80.

PMID: 14043754

In view of the risk of introduction of yellow fever into South-East Asia, comparative studies have been made of yellow fever vaccination in Malayan volunteers with a high prevalence of antibody to related viruses and in volunteers without related antibody. In a previous paper the neutralizing antibody responses of these volunteers were reported. The present paper describes the haemagglutinin-inhibiting (HI) antibody responses of the same groups of volunteers and discusses the relationship of these responses to the neutralizing antibody responses.The HI responses to yellow fever following vaccination closely paralleled the neutralizing antibody responses whether vaccination was subcutaneous or by multiple puncture. Volunteers with a high level of YF HI antibody due to infection with other group B viruses were found to be less likely to show a significant YF HI response than those without antibody. 90% of HI responses could be detected by the 21st day after vaccination.As with neutralizing antibody responses, volunteers given vaccine doses of 50-500 mouse intracerebral LD(50) subcutaneously gave greater responses than those given higher doses.

Matched MeSH terms: Tropical Medicine*

Fulltext Filariasis of the axilla in a patient returning from travel abroad: a case report

Roethlisberger M, Wuerstlein R, Majores M, Müller-Stöver I, Seitz HM, Rhiem K, et al.

Breast care (Basel, Switzerland), 2012 Dec;7(6):487-9.

PMID: 24715832 DOI: 10.1159/000345471

BACKGROUND: The term filariasis comprises a group of parasitic infections caused by helminths belonging to different genera in the superfamily Filaroidea. The human parasites occur mainly in tropical and subtropical regions, but filariae are also found in temperate climates, where they can infect wild and domestic animals. Humans are rarely infected by these zoonotic parasites.

PATIENTS AND METHODS: A 55-year-old patient presented with a new-onset, subcutaneous, non-tender palpable mass in the right axilla. Ultrasonography showed a 1.3-cm, solid, singular encapsulated node. Sonography of the breast on both sides, axilla and lymphatic drainage on the left side, lymphatic drainage on the right side, and mammography on both sides were without pathological findings. The node was excised under local anesthesia as the patient refused minimal invasive biopsy.

RESULTS: On histopathological examination, the tail of a parasite of the group of filariae was found. The patient revealed that she had stayed in Africa and Malaysia for professional reasons. 6 months before the time of diagnosis, she had also suffered from a fever and poor general condition after a trip abroad. The patient was referred for further treatment to the Institute for Tropical Medicine at the University of Dusseldorf, where a treatment with ivermectin was conducted on the basis of positive staining with antibodies against filariae.

CONCLUSION: Our case demonstrates the importance of interdisciplinary collaboration between breast center, pathology, and other specialties such as microbiology and tropical medicine.

Matched MeSH terms: Tropical Medicine

Fever and rash in a returning traveller

Kumar N, Lewis DJ

BMJ, 2012;344:e2400.

PMID: 22496299 DOI: 10.1136/bmj.e2400

Matched MeSH terms: Tropical Medicine

Fulltext The etiology of beri-beri

Manson P

Br Med J, 1909;1(2521):1007-1009.

[Malaya in full text]

Matched MeSH terms: Tropical Medicine

Low and declining attack rates of imported typhoid fever in the Netherlands 1997-2014, in spite of a restricted vaccination policy

Suryapranata FS, Prins M, Sonder GJ

BMC Infect Dis, 2016 12 01;16(1):731.

PMID: 27905890

BACKGROUND: Typhoid fever mainly occurs in (sub) tropical regions where sanitary conditions remain poor. In other regions it occurs mainly among returning travelers or their direct contacts. The aim of this study was to evaluate the current Dutch guidelines for typhoid vaccination.

METHOD: Crude annual attack rates (AR) per 100,000 Dutch travelers were calculated during the period 1997 to 2014 by dividing the number of typhoid fever cases by the estimated total number of travelers to a specific country or region. Regions of exposure and possible risk factors were evaluated.

RESULTS: During the study period 607 cases of typhoid fever were reported. Most cases were imported from Asia (60%). Almost half of the cases were ethnically related to typhoid risk regions and 37% were cases visiting friends and relatives. The overall ARs for travelers to all regions declined significantly. Countries with the highest ARs were India (29 per 100,000), Indonesia (8 per 100,000), and Morocco (10 per 100,000). There was a significant decline in ARs among travelers to popular travel destinations such as Morocco, Turkey, and Indonesia. ARs among travelers to intermediate-risk areas according to the Dutch guidelines such as Latin America or Sub-Saharan Africa remained very low, despite the restricted vaccination policy for these areas compared to many other guidelines.

CONCLUSION: The overall AR of typhoid fever among travelers returning to the Netherlands is very low and has declined in the past 20 years. The Dutch vaccination policy not to vaccinate short-term travelers to Latin-America, Sub-Saharan Africa, Thailand and Malaysia seems to be justified, because the ARs for these destinations remain very low. These results suggest that further restriction of the Dutch vaccination policy is justified.

Matched MeSH terms: Tropical Medicine

[The relation of the faculty of veterinary medicine with the tropics: from developig assistance-projects to international cooporation 1987-2007]

Paling RW

Argos, 2008.

PMID: 20642142

In the introduction three stages are distinguished in the relation between the Faculty of Veterinary Medicine and the tropics: (1) Development of a veterinary infrastructure (research and education) in the former colonies, Netherlands-Indies, Surinam and The Netherlands Antilles (1850 - ca. 1949); (2) Developing Aid Assistance (1965-2000) and (3) Cooperation on the basis of bilateral treaties that express the mutual interests of the two countries involved (1993-today). The Faculty in Utrecht entered into such alliances with sister faculties in Thailand, South-Africa and Malaysia. As a result of internal and external factors the study of tropical veterinary medicine was no longer core business of the Faculty of Veterinary Medicine in Utrecht. Tropical veterinary medicine was incorporated in the Department of Parasitology and Tropical Veterinary Medicine. The Office for International Cooperation of the Faculty of Veterinary Medicine, founded in 1987, partly took over the role of the former institute. Its activities are education and information, research support of the ongoing projects and networking. The accent moved from aid to cooperation for mutual interest.

Matched MeSH terms: Tropical Medicine/history*

Displaying publications 41 - 60 of 64 in total