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Fulltext Development of folliculitis in a patient with recalcitrant pustular psoriasis following acitretin treatment: A case report

Nur Ashikin Ahmad, Tarita Taib, Meera Kuppusamy

Journal of Clinical and Health Sciences, 2017;2(1):48-51.
MyJurnal

Oral retinoids are among the drugs of choice for pustular psoriasis. Therapy with retinoids, including acitretin, is potent teratogens with other common side effects such as mucocutaneous involvement. Mucocutaneous side effects including dry lips (cheilitis), skin peeling, hair loss (alopecia), dry skin, or rhinitis are dose-related, with cheilitis occurring in more than 75% of patients receiving the highest doses of acitretin (75 mg/day). We report on a 37-year-old woman who developed folliculitis with acitretin which is a rare cutaneous side effect. She presented with eruptions pruritic papules with follicular pattern on anterior thigh and forearms after almost 1 year of treatment with acitretin (50mg OD) for pustular psoriasis. The skin lesion was treated successfully with skin dressing and antibiotic treatment and skin biopsy is suggestive of folliculitis. Several treatments for pustular psoriasis including topical steroids, methotrexate and oral prednisolone were ineffective or not tolerated. Treatment with acitretin which are 50mg OD provided partial resolution of skin lesions. The case is hereby reported because of its rarity and folliculitis must be considered in the differential diagnosis of a popular eruption, especially in patients with high dose acitretin.

Matched MeSH terms: Forearm
Fulltext Pulled/nursemaid’s elbow

Mohd Miswan M. F., Mohamad Saifudin Othman, Ferdhany Muhamad Effendi, Khairul Nizam Rozali, Mohd Ikraam Ibrahim

Malays Fam Physician, 2017;12(1):26-28.
MyJurnal

Nursemaid’s elbow is a radial head subluxation caused by axial traction on the extended arm while
the forearm is pronated, allowing for slippage of the radial head. A 2-year-old boy presented with
pain, swelling and reduced range of movement of the right elbow for 4 days. The mother noted that
the child was moving the right upper limb less often and there was tenderness over the right elbow.
X-ray of the right elbow showed subluxation of the elbow joint with no obvious fracture. A trial of
conservative management was decided upon and the patient was placed on a right elbow backslab
with the right forearm in a supine position. On follow-up, there was no swelling, tenderness or
neurological deficit noted. A repeate x-ray revealed normal findings.

Matched MeSH terms: Forearm
Skin lightening properties of zerumbone cream: A placebo-controlled study

Kuek WN, Tiang YR, Yow HY, Tan LKS, How CW, Looi QHD, et al.

J Cosmet Dermatol, 2024 Jun;23(6):2117-2124.
PMID: 38366687 DOI: 10.1111/jocd.16234

OBJECTIVE: Despite the demonstrated anti-melanogenic and UV protective effects of Zerumbone (ZER) in vitro, there is a lack of clinical trials that have been done to assess these properties. The primary objective of this study was to assess the effectiveness of ZER in lightening the skin tone of human participants with a single-blind approach.
METHODS: Twenty-six participants were randomly assigned to two groups to investigate the application location (left or right volar forearm) for the placebo and ZER creams. Both creams were topically administered to the volar forearms twice daily over a duration of 4 weeks. Initial skin irritation was assessed before and 30 min after applying creams. The melanin and erythema levels were quantified with Mexameter MX 18.
RESULTS: Twenty participants were included in the analysis. The cream formulation had excellent physical properties and was well-received by the participants. The initial skin irritation study results indicated that neither of the creams elicited an allergic reaction. The administration of ZER cream resulted in a statistically significant reduction in melanin levels (p

Matched MeSH terms: Forearm
Autogenous forearm loop arteriovenous fistula creation

Tang WJ, Mat Saad AZ

J Vasc Access, 2018 Mar;19(2):191-194.
PMID: 29148006 DOI: 10.5301/jva.5000801

INTRODUCTION: Arteriovenous fistula is a lifeline for end-stage kidney disease patients on dialysis. The quality of the vein and artery to be used plays a crucial role in attaining a functioning, reliable and long-lasting arteriovenous fistula. The aim of the study is to present an alternative for haemodialysis access to preserve the upper arm vasculature for future use - the forearm loop arteriovenous fistula.
METHODS: From October 2015 to September 2016, 202 patients with chronic kidney disease (CKD), stages 4 and 5, underwent arteriovenous fistula creation at the Universiti Sains Malaysia Hospital, Malaysia. Nine patients, with severe atherosclerosis of the distal artery, but with satisfactory veins, underwent forearm loop arteriovenous fistula creation. Maturation of the fistula was based on the classification by the National Kidney Foundation Kidney Disease Outcomes Quality Initiative (NKF KDOQI).
RESULTS: All nine patients who underwent forearm loop arteriovenous fistula have had diabetes mellitus for more than 10 years. Only one fistula failed to mature within 6 weeks. Two arteriovenous fistulas thrombosed at 3 and 5 months, respectively, after the commencement of haemodialysis. However, the other six matured fistulas are still functioning well after a year of regular usage.
CONCLUSIONS: Distal forearm arteries in diabetics may be severely atherosclerotic. Forearm loop arteriovenous fistula can be considered as the primary access for cases decided as inconvenient for fistula creation due to severe occlusive atherosclerotic disease of the forearm arteries; in order to preserve upper arm veins for future access procedures.

Matched MeSH terms: Forearm/blood supply*