MyMedR

Association of ADRA2A and MTHFR gene polymorphisms with weight loss following antipsychotic switching to aripiprazole or ziprasidone

Roffeei SN, Reynolds GP, Zainal NZ, Said MA, Hatim A, Aida SA, et al.

Hum Psychopharmacol, 2014 Jan;29(1):38-45.

PMID: 24424705 DOI: 10.1002/hup.2366

Various genetic polymorphisms have been reported to be associated with antipsychotic-induced weight gain. In this study, we aimed to determine whether risk polymorphisms in 12 candidate genes are associated with reduction in body mass index (BMI) of patients following switching of antipsychotics to aripiprazole or ziprasidone.

Religiousness, religious coping methods and distress level among psychiatric patients in Malaysia

Nurasikin MS, Khatijah LA, Aini A, Ramli M, Aida SA, Zainal NZ, et al.

Int J Soc Psychiatry, 2013 Jun;59(4):332-8.

PMID: 22408116 DOI: 10.1177/0020764012437127

Patients having psychiatric diagnoses often experience high level of distress. Religiousness is often used by them as part of their coping mechanism and problem-solving strategies.

Validation of the Malay version of the Multidimensional Scale of Perceived Social Support (MSPSS-M) among a group of medical students in Faculty of Medicine, University Malaya

Ng CG, Amer Siddiq AN, Aida SA, Zainal NZ, Koh OH

Asian J Psychiatr, 2010 Mar;3(1):3-6.

PMID: 23051129 DOI: 10.1016/j.ajp.2009.12.001

OBJECTIVE: The aim of this study was to validate the Malay version of the Multidimensional Scale of Perceived Social Support (MSPSS-M) among a group of medical students in Faculty of Medicine, University Malaya.
METHODS: 237 students participated in the study. They were given the Malay version of MSPSS, medical outcome study (MOS) social support survey, Malay version of General Health Questionnaire (GHQ), Malay version of Beck Depression Inventory (BDI) and English version of MSPSS. A week later, these students were again given the Malay version of MSPSS.
RESULTS: The instrument displayed good internal consistency (Cronbach's alpha=0.89), parallel form reliability (0.94) and test-retest reliability (0.77) (Spearman's rho, p<0.01). The negative correlation of the total and subscales of the instrument with the Malay version of GHQ and BDI confirmed its validity. Extraction method of the 12 items MSPSS using principle axis factoring with direct oblimin rotation converged into three factors of perceived social support (Family, Friends and Significant Others) with reliability coefficients of 0.88, 0.82 and 0.94, respectively.
CONCLUSION: The Malay version of the MSPSS demonstrated good psychometric properties in measuring social support among a group of medical students from Faculty of Medicine, University Malaya and it could be used as a simple instrument on young educated Malaysian adolescents.

Prevalence of psychiatric disorders among juvenile offenders in Malaysian prisons and association with socio-demographic and personal factors

Aida SA, Aili HH, Manveen KS, Salwina WI, Subash KP, Ng CG, et al.

Int J Prison Health, 2014;10(2):132-43.

PMID: 25764076 DOI: 10.1108/IJPH-06-2013-0029

The number of juvenile offenders admitted to Malaysian prisons is alarming. The purpose of this paper is to determine the presence of any psychiatric disorders and their association with personal characteristics of juvenile detainees in prisons across Peninsular Malaysia.

Association of FTO, LEPR and MTHFR gene polymorphisms with metabolic syndrome in schizophrenia patients receiving antipsychotics

Roffeei SN, Mohamed Z, Reynolds GP, Said MA, Hatim A, Mohamed EH, et al.

Pharmacogenomics, 2014 Mar;15(4):477-85.

PMID: 24624915 DOI: 10.2217/pgs.13.220

The occurrence of metabolic syndrome (MS) in schizophrenia patients receiving long-term antipsychotics (APs) contributes to their high mortality rate. We aimed to determine whether genetic polymorphisms of identified candidate genes are associated with MS in our study population.

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