Association of FTO, LEPR and MTHFR gene polymorphisms with metabolic syndrome in schizophrenia patients receiving antipsychotics

Roffeei SN 1 , Mohamed Z , Reynolds GP , Said MA , Hatim A , Mohamed EH Show all authors , Aida SA , Zainal NZ

Affiliations 

  • 1 Pharmacogenomics Laboratory, Department of Pharmacology, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia
Pharmacogenomics, 2014 Mar;15(4):477-85.
PMID: 24624915 DOI: 10.2217/pgs.13.220

Abstract

The occurrence of metabolic syndrome (MS) in schizophrenia patients receiving long-term antipsychotics (APs) contributes to their high mortality rate. We aimed to determine whether genetic polymorphisms of identified candidate genes are associated with MS in our study population.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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