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  1. ELEXSON NILLIAN, AMIZA NUR, DIYANA NUR, AMIRAH ZAKIRAH, GRACE BEBEY
    MyJurnal
    Contamination of drinks with E. coli O157:H7 served in food premises such as restaurants can cause haemorrhagic colitis and haemolytic uremic syndrome to humans. The presence or absence of faecal pathogen was demonstrated using coliform group as indicator microorganisms. Therefore, this study was conducted to detect the presence of E. coli O157:H7 in drinking water from food restaurant premise in Kota Samarahan and Kuching to ensure safe and potable drinking water is served to the consumer. A total of thirty (n=30) drink samples including six types of each of the samples are cold plain water, iced tea, iced milo, syrup and iced milk tea. Most Probable Number (MPN) procedure was used in this study to enumerate the MPN values of coliform bacteria in each drink collected. A total of 53.33% (16/30) of the drink samples showed positive E. coli detection. Then, the PCR assay showed 6.25% (one out of 16 isolates) samples were positive and carried stx1 gene produced by E. coli O157:H7 in iced milo sample types. This study showed the drinks collected from food premises was contaminated with faecal contamination, which was not safe to drink by the consumer. Therefore, preventive actions should be taken to prevent foodborne illness outbreak in future
  2. Micky Vincent, Latifah Suali, Afizul Safwan Azahari, Patricia Rowena Mark Baran, Elexson Nillian, Lesley Maurice Bilung
    MyJurnal
    Yeast growth and biomass production are greatly influenced by the length of the
    incubation period during cultivation. Therefore, this study was conducted to
    investigate the growth kinetics of five Lipomyces starkeyi strains as determined by
    biomass production. The five L. starkeyi strains, namely L. starkeyi ATCC 12659, L.
    starkeyi MV-1, L. starkeyi MV-4, L. starkeyi MV-5 and L. starkeyi MV-8, were inoculated
    in sterilized Yeast Malt broth, and, incubated for 192 hr at ambient temperature.
    Biomass yields were assessed and calculated gravimetrically every 24 hr. Results
    indicated that the optimal biomass production of L. starkeyi ATCC 12659, L. starkeyi
    MV-1, L. starkeyi MV-4, L. starkeyi MV-5 and L. starkeyi MV-8 were at 120, 168, 144,
    168 and 120 hr, with the concentrations of 6.64, 6.43, 9.78, 11.23 and 8.56 g/L,
    respectively. These results indicate that each L. starkeyi strain requires specific
    incubation period for the optimum production of fungal biomass. Therefore, by
    cultivating each L. starkeyi strain at the predetermined incubation period, biomass
    yields could significantly be improved for further downstream applications such as
    single cell protein and lipid production.
  3. Elexson Nillian, Malini Mathialagan, Samuel Lihan, Grace Bebey, Patrick Guda Benjamin
    MyJurnal
    Kaempferia galangal rhizome is one of the traditional medicinal plant species in
    Zingiberaceae family and well known as “cekur” in Borneo. Rapid emergence of
    multidrug resistance of V. cholerae biofilm has increased the failure of antibiotic
    treatment in recent years. This research was designed to demonstrate the
    antimicrobial activity of K. galangal rhizome extract against twenty six (n=26) V. cholera
    biofilm which were isolated from outbreak in Limbang, Sarawak in 2016. K. galangal
    rhizome was analyzed by methanol extraction and tested against biofilm of V. cholerae.
    The susceptibility of V. cholerae towards K. galangal rhizome was evaluated using disk
    diffusion method which showed a maximum zone of inhibition of 12.0 mm at 1000
    mg/mL concentration. As a result, the MBEC50 of V. cholerae was between 125 mg/mL
    to 250 mg/mL while more than 90% biofilm eradication (MBEC90) was achieved by 500
    mg/mL extract concentration. Extract-treated cell showed change in the morphology
    of V. cholerae by destruction of cell wall. K. galangal rhizome extract acts as a potent
    antibiofilm agent with dual actions by preventing and eradicating the biofilm of V.
    cholerae.
  4. Dayang Najwa AB, Elexson N, Dalene L, Teng ST
    Microb Ecol, 2024 Mar 15;87(1):51.
    PMID: 38488929 DOI: 10.1007/s00248-024-02356-5
    In aquatic environments, Vibrio and cyanobacteria establish varying relationships influenced by environmental factors. To investigate their association, this study spanned 5 months at a local shrimp farm, covering the shrimp larvae stocking cycle until harvesting. A total of 32 samples were collected from pond A (n = 6), pond B (n = 6), effluent (n = 10), and influent (n = 10). Vibrio species and cyanobacteria density were observed, and canonical correspondence analysis (CCA) assessed their correlation. CCA revealed a minor correlation (p = 0.847, 0.255, 0.288, and 0.304) between Vibrio and cyanobacteria in pond A, pond B, effluent, and influent water, respectively. Notably, Vibrio showed a stronger correlation with pH (6.14-7.64), while cyanobacteria correlated with pH, salinity (17.4-24 ppt), and temperature (30.8-31.5 °C), with salinity as the most influential factor. This suggests that factors beyond cyanobacteria influence Vibrio survival. Future research could explore species-specific relationships, regional dynamics, and multidimensional landscapes to better understand Vibrio-cyanobacteria connections. Managing water parameters may prove more efficient in controlling vibriosis in shrimp farms than targeting cyanobacterial populations.
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