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  1. Nguyen TB, Nguyen TK, Chen CW, Chen WH, Bui XT, Lam SS, et al.
    Bioresour Technol, 2023 Aug;382:129182.
    PMID: 37210031 DOI: 10.1016/j.biortech.2023.129182
    In this study, biochar produced from sunflower seeds husk was activated through ZnCl2 to support the NiCo2O4 nanoparticles (NiCo2O4@ZSF) in catalytic activation of peroxymonosulfate (PMS) toward tetracycline (TC) removal from aqueous solution. The good dispersion of NiCo2O4 NPs on the ZSF surface provided sufficient active sites and abundant functional groups for the adsorption and catalytic reaction. The NiCo2O4@ZSF activating PMS showed high removal efficiency up to 99% after 30 min under optimal condition ([NiCo2O4@ZSF] = 25 mg L-1, [PMS] = 0.04 mM, [TC] = 0.02 mM and pH = 7). The catalyst also exhibited good adsorption performance with a maximum adsorption capacity of 322.58 mg g-1. Sulfate radicals (SO4•-), superoxide radical (O2•-), and singlet oxygen (1O2) played a decisive role in the NiCo2O4@ZSF/PMS system. In conclusion, our research elucidated the production of highly efficient carbon-based catalysts for environmental remediation, and also emphasized the potential application of NiCo2O4 doped biochar.
  2. Ng SM, Malene IV, Nguyen TK, Le K, Lim YXL, Lek N, et al.
    BMC Endocr Disord, 2023 Nov 16;23(1):249.
    PMID: 37974071 DOI: 10.1186/s12902-023-01501-4
    BACKGROUND: There is minimal data of health outcomes for Type 1 Diabetes (T1D) in Southeast Asia (SEA) where government funding of insulin and blood glucose monitoring either do not exist or is limited. The full impact of Covid-19 pandemic on the national economies of SEA remain unknown. In the midst of the pandemic, in 2021, HelloType1 was developed by Action4Diabetes (A4D), a non-government organisation charity in collaboration with Southeast Asia local healthcare professionals as an innovative digital educational resource platform of T1D in local languages. HelloType1 was launched in Cambodia, Vietnam, Thailand and Malaysia in 2021 to 2022 with Memorandums of Understandings (MOUs) signed between A4D and each country. Internet data analytics were undertaken between the 1st of January 2022 to 31st of December 2022.

    AIMS: The aims of this study were to explore the usability and internet data analytics of the HelloType1 online educational platform within each country.

    METHODS: The data analytics were extracted Google analytics that tracks data from the website hellotype1.com and Facebook analytics associated with the website.

    RESULTS: There was a 147% increase in the number of HelloType1 users between the first 6 months versus the latter 6 months in 2022 and a 15% increase in the number of pages visited were noted. The majority of traffic source were coming from organic searches with a significant increase of 80% growth in 2022.

    CONCLUSIONS: The results of the analytics provide important insights on how an innovative diabetes digital educational resource in local languages may be optimally delivered in low-middle income countries with limited resources.

  3. Kong APS, Lew T, Lau ESH, Lim LL, Kesavadev J, Jia W, et al.
    Diabetes Obes Metab, 2020 04;22(4):669-679.
    PMID: 31903728 DOI: 10.1111/dom.13950
    AIMS: To explore the pattern of insulin use and glycaemic control in Asian people with type 2 diabetes, stratified by gender, young-onset diabetes (YOD; diagnosed before age 40 years), and diabetic kidney disease (DKD; estimated glomerular filtration rate [eGFR] 
  4. Lim LL, Lau ESH, Kong APS, Fu AWC, Lau V, Jia W, et al.
    Lancet Reg Health West Pac, 2023 Mar;32:100663.
    PMID: 36785858 DOI: 10.1016/j.lanwpc.2022.100663
    BACKGROUND: In Asia, diabetes-associated death due to cardiorenal diseases were 2-3 times higher in women than men which might be due to gender disparity in quality of care and health habits.

    METHODS: Adults with type 2 diabetes (T2D) from 11 Asian countries/areas were assessed using the same protocol (2007-2015). We compared treatment target attainment (HbA1c < 7%, blood pressure [BP] < 130/80 mmHg, risk-based LDL-cholesterol, lack of central obesity [waist circumference <90 cm in men or <80 cm in women), use of cardiorenal-protective drugs (renin-angiotensin system [RAS] inhibitors, statins), and self-reported health habits including self-monitoring blood glucose (SMBG) by gender. Analyses were stratified by countries/areas, age of natural menopause (<50 vs. ≥50 years), and comorbidities (atherosclerotic cardiovascular disease [ASCVD], heart failure, kidney impairment [eGFR < 60 mL/min/1.73 m2]).

    FINDINGS: Among 106,376 patients (53.2% men; median (interquartile range) diabetes duration: 6.0 (2.0-12.0) years; mean ± SD HbA1c 8.0 ± 1.9%; 27% insulin-treated), women were older and less likely to receive college education than men (28.9% vs. 48.8%). Women were less likely to smoke/drink alcohol and were physically less active than men. Women had lower BP (<130/80 mmHg: 29.4% vs. 25.7%), less general obesity (54.8% vs. 57.8%) but more central obesity than men (77.5% vs. 57.3%). Women were less likely to have ASCVD (12.8% vs. 17.0%) or heart failure (1.3% vs. 2.3%), but more likely to have kidney impairment (22.3% vs. 17.6%) and any-site cancer than men (2.5% vs. 1.6%). In most countries/areas, more men attained HbA1c <7% and risk-based LDL-cholesterol level than women. After adjusting for potential confounders including countries and centres, men had 1.63 odds ratio (95% CI 1.51, 1.74) of attaining ≥3 treatment targets than women.

    INTERPRETATION: Asian women with T2D had worse quality of care than men especially in middle-income countries/areas, calling for targeted implementation programs to close these care gaps.

    SPONSOR: Asia Diabetes Foundation.

    FUNDING: Nil.

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