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Arrhythmia detection using deep convolutional neural network with long duration ECG signals

Yıldırım Ö, Pławiak P, Tan RS, Acharya UR

Comput Biol Med, 2018 11 01;102:411-420.
PMID: 30245122 DOI: 10.1016/j.compbiomed.2018.09.009

This article presents a new deep learning approach for cardiac arrhythmia (17 classes) detection based on long-duration electrocardiography (ECG) signal analysis. Cardiovascular disease prevention is one of the most important tasks of any health care system as about 50 million people are at risk of heart disease in the world. Although automatic analysis of ECG signal is very popular, current methods are not satisfactory. The goal of our research was to design a new method based on deep learning to efficiently and quickly classify cardiac arrhythmias. Described research are based on 1000 ECG signal fragments from the MIT - BIH Arrhythmia database for one lead (MLII) from 45 persons. Approach based on the analysis of 10-s ECG signal fragments (not a single QRS complex) is applied (on average, 13 times less classifications/analysis). A complete end-to-end structure was designed instead of the hand-crafted feature extraction and selection used in traditional methods. Our main contribution is to design a new 1D-Convolutional Neural Network model (1D-CNN). The proposed method is 1) efficient, 2) fast (real-time classification) 3) non-complex and 4) simple to use (combined feature extraction and selection, and classification in one stage). Deep 1D-CNN achieved a recognition overall accuracy of 17 cardiac arrhythmia disorders (classes) at a level of 91.33% and classification time per single sample of 0.015 s. Compared to the current research, our results are one of the best results to date, and our solution can be implemented in mobile devices and cloud computing.
A new machine learning technique for an accurate diagnosis of coronary artery disease

Abdar M, Książek W, Acharya UR, Tan RS, Makarenkov V, Pławiak P

Comput Methods Programs Biomed, 2019 Oct;179:104992.
PMID: 31443858 DOI: 10.1016/j.cmpb.2019.104992

BACKGROUND AND OBJECTIVE: Coronary artery disease (CAD) is one of the commonest diseases around the world. An early and accurate diagnosis of CAD allows a timely administration of appropriate treatment and helps to reduce the mortality. Herein, we describe an innovative machine learning methodology that enables an accurate detection of CAD and apply it to data collected from Iranian patients.
METHODS: We first tested ten traditional machine learning algorithms, and then the three-best performing algorithms (three types of SVM) were used in the rest of the study. To improve the performance of these algorithms, a data preprocessing with normalization was carried out. Moreover, a genetic algorithm and particle swarm optimization, coupled with stratified 10-fold cross-validation, were used twice: for optimization of classifier parameters and for parallel selection of features.
RESULTS: The presented approach enhanced the performance of all traditional machine learning algorithms used in this study. We also introduced a new optimization technique called N2Genetic optimizer (a new genetic training). Our experiments demonstrated that N2Genetic-nuSVM provided the accuracy of 93.08% and F1-score of 91.51% when predicting CAD outcomes among the patients included in a well-known Z-Alizadeh Sani dataset. These results are competitive and comparable to the best results in the field.
CONCLUSIONS: We showed that machine-learning techniques optimized by the proposed approach, can lead to highly accurate models intended for both clinical and research use.
Fulltext Application of Computational Intelligence Methods for the Automated Identification of Paper-Ink Samples Based on LIBS

Rzecki K, Sośnicki T, Baran M, Niedźwiecki M, Król M, Łojewski T, et al.

Sensors (Basel), 2018 Oct 29;18(11).
PMID: 30380626 DOI: 10.3390/s18113670

Laser-induced breakdown spectroscopy (LIBS) is an important analysis technique with applications in many industrial branches and fields of scientific research. Nowadays, the advantages of LIBS are impaired by the main drawback in the interpretation of obtained spectra and identification of observed spectral lines. This procedure is highly time-consuming since it is essentially based on the comparison of lines present in the spectrum with the literature database. This paper proposes the use of various computational intelligence methods to develop a reliable and fast classification of quasi-destructively acquired LIBS spectra into a set of predefined classes. We focus on a specific problem of classification of paper-ink samples into 30 separate, predefined classes. For each of 30 classes (10 pens of each of 5 ink types combined with 10 sheets of 5 paper types plus empty pages), 100 LIBS spectra are collected. Four variants of preprocessing, seven classifiers (decision trees, random forest, k-nearest neighbor, support vector machine, probabilistic neural network, multi-layer perceptron, and generalized regression neural network), 5-fold stratified cross-validation, and a test on an independent set (for methods evaluation) scenarios are employed. Our developed system yielded an accuracy of 99.08%, obtained using the random forest classifier. Our results clearly demonstrates that machine learning methods can be used to identify the paper-ink samples based on LIBS reliably at a faster rate.
An intrusion detection model to detect zero-day attacks in unseen data using machine learning

Dai Z, Por LY, Chen YL, Yang J, Ku CS, Alizadehsani R, et al.

PLoS One, 2024;19(9):e0308469.
PMID: 39259729 DOI: 10.1371/journal.pone.0308469

In an era marked by pervasive digital connectivity, cybersecurity concerns have escalated. The rapid evolution of technology has led to a spectrum of cyber threats, including sophisticated zero-day attacks. This research addresses the challenge of existing intrusion detection systems in identifying zero-day attacks using the CIC-MalMem-2022 dataset and autoencoders for anomaly detection. The trained autoencoder is integrated with XGBoost and Random Forest, resulting in the models XGBoost-AE and Random Forest-AE. The study demonstrates that incorporating an anomaly detector into traditional models significantly enhances performance. The Random Forest-AE model achieved 100% accuracy, precision, recall, F1 score, and Matthews Correlation Coefficient (MCC), outperforming the methods proposed by Balasubramanian et al., Khan, Mezina et al., Smith et al., and Dener et al. When tested on unseen data, the Random Forest-AE model achieved an accuracy of 99.9892%, precision of 100%, recall of 99.9803%, F1 score of 99.9901%, and MCC of 99.8313%. This research highlights the effectiveness of the proposed model in maintaining high accuracy even with previously unseen data.
Fulltext Stages prediction of Alzheimer's disease with shallow 2D and 3D CNNs from intelligently selected neuroimaging data

Ur Rahman J, Hanif M, Ur Rehman O, Haider U, Mian Qaisar S, Pławiak P

Sci Rep, 2025 Mar 18;15(1):9238.
PMID: 40102464 DOI: 10.1038/s41598-025-93560-x

Detection of Alzheimer's Disease (AD) is critical for successful diagnosis and treatment, involving the common practice of screening for Mild Cognitive Impairment (MCI). However, the progressive nature of AD makes it challenging to identify its causal factors. Modern diagnostic workflows for AD use cognitive tests, neurological examinations, and biomarker-based methods, e.g., cerebrospinal fluid (CSF) analysis and positron emission tomography (PET) imaging. While these methods are effective, non-invasive imaging techniques like Magnetic Resonance Imaging (MRI) are gaining importance. Deep Learning (DL) approaches for evaluating alterations in brain structure have focused on combining MRI and Convolutional Neural Networks (CNNs) within the spatial architecture of DL. This combination has garnered significant research interest due to its remarkable effectiveness in automating feature extraction across various multilayer perceptron models. Despite this, MRI's noisy and multidimensional nature requires an intelligent preprocessing pipeline for effective disease prediction. Our study aims to detect different stages of AD from the multidimensional neuroimaging data obtained through MRI scans using 2D and 3D CNN architectures. The proposed preprocessing pipeline comprises skull stripping, spatial normalization, and smoothing. It is followed by a novel and efficient pixel count-based frame selection and cropping approach, which renders a notable dimension reduction. Furthermore, the learnable resizer method is applied to enhance the image quality while resizing the data. Finally, the proposed shallow 2D and 3D CNN architectures extract spatio-temporal attributes from the segmented MRI data. Furthermore, we merged both the CNNs for further comparative analysis. Notably, 2D CNN achieved a maximum accuracy of 93%, while 3D CNN reported the highest accuracy of 96.5%.
Image steganalysis using active learning and hyperparameter optimization

Bohang L, Li N, Yang J, Alfarraj O, Albelhai F, Tolba A, et al.

Sci Rep, 2025 Mar 01;15(1):7340.
PMID: 40025136 DOI: 10.1038/s41598-025-92082-w

Image steganalysis, detecting hidden data in digital images, is essential for enhancing digital security. Traditional steganalysis methods typically rely on large, pre-labeled image datasets, which are difficult and costly to compile. To address this, this paper introduces an innovative approach that combines active learning and off-policy Deep Reinforcement Learning (DRL) to improve image steganalysis with minimal labeled data. Active learning allows the model to intelligently choose which unlabeled images should be annotated, thus reducing the amount of labeled data needed for effective training. Traditional active learning strategies often use static selection methods that restrict flexibility and do not adjust well to dynamic environments. To overcome this, our method incorporates off-policy DRL for strategic data selection. The off-policy in DRL can increase sample efficiency and significantly enhance learning outcomes. We also use the Differential Evolution (DE) algorithm to fine-tune the hyperparameters of the model, reducing its sensitivity to different settings and ensuring more stable results. Our testing on the extensive BossBase 1.01 and BOWS-2 datasets demonstrates the robust ability of the approach to distinguish between unaltered and steganographic images, achieving an average F-measure of 93.152% on BossBase 1.01 and 91.834% on the BOWS-2 dataset. In summary, this research enhances digital security by employing advanced image steganalysis to detect hidden data, significantly improving detection accuracy with minimal labeled data.