MyMedR

Fulltext A persistent left superior vena cava

Paval J, Nayak S

Singapore Med J, 2007 Mar;48(3):e90-3.

Persistent left superior vena cava is the most common form of anomalous venous drainage involving the superior vena cava, and represents persistence of the left horn of the embryonic sinus venosus, which normally involutes during normal development to become the coronary sinus. Almost always, a persistent left superior vena cava enters the right atrium through the orifice of an enlarged coronary sinus. In this case report of a 60-year-old male cadaver, we describe a persistent left superior vena cava and discuss its embryology and clinical significance.

Effect of ascorbic acid on the monosodium glutamate-induced neurobehavioral changes in periadolescent rats

Narayanan SN, Kumar RS, Paval J, Nayak S

Bratisl Lek Listy, 2010;111(5):247-52.

PMID: 20568412

In the current study we evaluated adverse effects of monosodium glutamate (MSG) on memory formation and its retrieval as well as the role of ascorbic acid (Vitamin-C) in prevention of MSG-induced alteration of neurobehavioral performance in periadolescent rats.

Analysis of emotionality and locomotion in radio-frequency electromagnetic radiation exposed rats

Narayanan SN, Kumar RS, Paval J, Kedage V, Bhat MS, Nayak S, et al.

Neurol Sci, 2013 Jul;34(7):1117-24.

PMID: 22976773 DOI: 10.1007/s10072-012-1189-4

In the current study the modulatory role of mobile phone radio-frequency electromagnetic radiation (RF-EMR) on emotionality and locomotion was evaluated in adolescent rats. Male albino Wistar rats (6-8 weeks old) were randomly assigned into the following groups having 12 animals in each group. Group I (Control): they remained in the home cage throughout the experimental period. Group II (Sham exposed): they were exposed to mobile phone in switch-off mode for 28 days, and Group III (RF-EMR exposed): they were exposed to RF-EMR (900 MHz) from an active GSM (Global system for mobile communications) mobile phone with a peak power density of 146.60 μW/cm(2) for 28 days. On 29th day, the animals were tested for emotionality and locomotion. Elevated plus maze (EPM) test revealed that, percentage of entries into the open arm, percentage of time spent on the open arm and distance travelled on the open arm were significantly reduced in the RF-EMR exposed rats. Rearing frequency and grooming frequency were also decreased in the RF-EMR exposed rats. Defecation boli count during the EPM test was more with the RF-EMR group. No statistically significant difference was found in total distance travelled, total arm entries, percentage of closed arm entries and parallelism index in the RF-EMR exposed rats compared to controls. Results indicate that mobile phone radiation could affect the emotionality of rats without affecting the general locomotion.

Anti-arthritic potential of the plant Justicia gendarussa Burm F

Paval J, Kaitheri SK, Potu BK, Govindan S, Kumar RS, Narayanan SN, et al.

Clinics (Sao Paulo), 2009;64(4):357-62.

PMID: 19488595

OBJECTIVE: To evaluate the anti-arthritic potential of the plant Justicia gendarussa using two different rat models.

MATERIALS AND METHOD: The anti-arthritic potential of the alcoholic extract of the plant Justicia gendarussa was evaluated using the Freund's adjuvant-induced and collagen-induced arthritic rat models. The rats were treated with the ethanolic extract of Justicia gendarussa and with standard aspirin.

RESULTS: The ethanolic extract of Justicia gendarussa showed significant anti-arthritic activity that was statistically similar to that of aspirin. Our results suggest that the alcoholic extract of Justicia gendarussa exhibits significant anti-arthritic potential.

Displaying all 4 publications