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Fulltext The Relationship between Skipping Breakfast and Dietary Intake with Body Mass Index of a Private University Students in Shah Alam, Malaysia

Yu Ke Xin, Suwandini Ambalavanan, Ainor Farahin Binti Aziz, Pravina Deligannu

Journal of Management & Science, 2021;19(1):70-78.
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Breakfast consumption is correlated with a range of positive outcomes, namely good academic performance, appropriate nutrient intake and body mass index (BMI). However, many university students have the habits of skipping breakfast and consume insufficient amount of nutrients. The aim of this study was to determine the relationship between the behaviour of skipping breakfast and dietary intake with BMI among students of a private university in Shah Alam, Malaysia. A cross sectional study was performed among 200 students, using a self-administered questionnaire. The questionnaire consisted of socio-demographics, dietary habits and 24-hour recall food intake. The data was analysed using SPSS and Nutritionist pro software. A total of 58% students (60% male and 56% female) had the habit of breakfast skipping. The common reason of student skipping breakfast is do not have time (n = 146; 73%). Most of the respondents taking more than 2500kcal daily were overweight. The results showed no significant association (p = 0.831) between breakfast skipping and BMI. There was no significant association (p > 0.05) between covariates (socio-demography, anthropometry, intakes of protein, carbohydrate, sodium, iron and vitamin C) with BMI of students. There was significant association (p = 0.001) between dietary intake (calorie) and BMI. In conclusion, it is evidenced that the dietary intake of these students influences their BMI status, instead of the behaviour of skipping breakfast. The importance of having breakfast should be emphasised among the university students, the students should prioritise their daily nutrient intake by taking regular breakfast.
Fulltext Larvicidal activity, inhibition effect on development, histopathological alteration and morphological aberration induced by seaweed extracts in Aedes aegypti (Diptera: Culicidae)

Yu KX, Wong CL, Ahmad R, Jantan I

Asian Pac J Trop Med, 2015 Dec;8(12):1006-1012.
PMID: 26706671 DOI: 10.1016/j.apjtm.2015.11.011

OBJECTIVE: To investigate the larvicidal activity, inhibition effect on development, histopathological alteration and morphological aberration induced by the extracts derived from seaweeds Bryopsis pennata (B. pennata), Sargassum binderi (S. binderi) and Padina australis in Aedes aegypti (Ae. aegypti) larvae and to characterize the phytochemical components of the three seaweeds.
METHODS: Larvicidal activity of the seaweeds towards the larvae of Ae. aegypti was determined according to WHO. The inhibition effect of seaweeds was assessed by determining the mortality, adult emergence rate, larval and pupa duration of the treated larvae. Histopathological effect on midgut epithelium of larvae and morphological aberration induced by the methanol extracts were examined. Phytochemical analysis was done to determine the presence of alkaloids, saponins, steroids and terpenoids in the seaweeds.
RESULTS: Chloroform partition of B. pennata extract exhibited the strongest larvicidal activity (LC50 = 82.55 μg/mL), followed by methanol extract of B. pennata (LC50 = 160.07 μg/mL) and chloroform partition of S. binderi extract (LC50 = 192.43 μg/mL). The methanol extract of S. binderi exhibited the strongest effect on prolongation of larval period (1.5-fold longer as compared to control) and resulted in strongest inhibition effect in adult emergence (98.67%). The histopathological study showed that larvae treated with seaweed extracts had cytopathological alteration of the midgut epithelium. The morphological observation revealed that the anal papillae and terminal spiracles of larvae were the common sites of aberrations.
CONCLUSIONS: The study provided information on various effects of seaweed extracts on Ae. aegypti. Further investigation on identifying the active compounds and their mechanisms of action is recommended.
The major bioactive components of seaweeds and their mosquitocidal potential

Yu KX, Jantan I, Ahmad R, Wong CL

Parasitol Res, 2014 Sep;113(9):3121-41.
PMID: 25115733 DOI: 10.1007/s00436-014-4068-5

Seaweeds are one of the most widely studied natural resources for their biological activities. Novel seaweed compounds with unique chemical structures have been reported for their pharmacological properties. The urge to search for novel insecticidal compound with a new mode of action for development of botanical insecticides supports the relevant scientific research on discovering the bioactive compounds in seaweeds. The mosquitocidal potential of seaweed extracts and their isolated compounds are documented in this review paper, along with the discussion on bioactivities of the major components of seaweeds such as polysaccharides, phenolics, proteins, terpenes, lipids, and halogenated compounds. The effects of seaweed extracts and compounds toward different life stages of mosquito (egg, larva, pupa, and adult), its growth, development, and reproduction are elaborated. The structure-activity relationships of mosquitocidal compounds are discussed to extrapolate the possible chemical characteristics of seaweed compounds responsible for insecticidal properties. Furthermore, the possible target sites and mode of actions of the mosquitocidal seaweed compounds are included in this paper. The potential synergistic effects between seaweeds and commercial insecticides as well as the toxic effects of seaweed extracts and compounds toward other insects and non-target organisms in the same habitat are also described. On top of that, various factors that influence the mosquitocidal potential of seaweeds, such as abiotic and biotic variables, sample preparation, test procedures, and considerations for a precise experimental design are discussed. The potential of active seaweed extracts and compounds in the development of effective bioinsecticide are also discussed.
Fulltext Mosquitocidal and Oviposition Repellent Activities of the Extracts of Seaweed Bryopsis pennata on Aedes aegypti and Aedes albopictus

Yu KX, Wong CL, Ahmad R, Jantan I

Molecules, 2015;20(8):14082-102.
PMID: 26247928 DOI: 10.3390/molecules200814082

The ever-increasing threat from infectious diseases and the development of insecticide resistance in mosquito populations drive the global search for new natural insecticides. The aims of this study were to evaluate the mosquitocidal activity of the extracts of seaweed Bryopsis pennata against dengue vectors Aedes aegypti and Aedes albopictus, and determine the seaweed's toxic effect on brine shrimp nauplii (as a non-target organism). In addition, the chemical compositions of the active larvicidal extract and fraction were analyzed by using liquid chromatography-mass spectrometry (LC-MS). Chloroform extract exhibited strong ovicidal activity (with LC50 values of 229.3 and 250.5 µg/mL) and larvicidal activity against Ae. aegypti and Ae. albopictus. The larvicidal potential of chloroform extract was further ascertained when its A7 fraction exhibited strong toxic effect against Ae. aegypti (LC50 = 4.7 µg/mL) and Ae. albopictus (LC50 = 5.3 µg/mL). LC-MS analysis of the chloroform extract gave a tentative identification of 13 compounds; Bis-(3-oxoundecyl) tetrasulfide was identified as the major compound in A7 fraction. Methanol extract showed strong repellent effect against female oviposition, along with weak adulticidal activity against mosquito and weak toxicity against brine shrimp nauplii. The mosquitocidal results of B. pennata suggest further investigation for the development of effective insecticide.