MyMedR

Non-haemoglobin liver iron was estimated in 275 presumably normal individuals from Kuala Lumpur and Singapore at necropsy. Liver Iron concentrations were highest during the first two years after birth but declined sharply during childhood. They then rose gradually and reached a value of 20 mg/100gm in adult males. Liver iron concentrations of childbearing women remained low and it was only after menopause that values in women rose to those of males. Liver iron stores increased with age to a plateau of about 300 mg in adults, suggesting that this value may represent the adult size for liver iron store. Among the three major ethnic groups in Malaysia and Singapore, Chinese, being in a better socio-eonomic class, had larger liver iron stores. The median liver iron concentrations of Malaysians and Singaporeans, on the whole, were lower than those reported from western populations and as many as 35 per cent of the women were in a subclinical state of iron deficiency.

Matched MeSH terms: Anemia, Hypochromic/epidemiology

Anaemia in pregnancy in an aboriginal population

Ong HC

J Trop Med Hyg, 1974 Jan;77(1):22-6.

PMID: 4811560

Matched MeSH terms: Anemia, Hypochromic/epidemiology

Serum levels of iron, folic acid and vitamin B 12 in the maternal and cord blood in the three major ethnic groups in Malaysia

Sindhu SS

Indian Pediatr, 1974 Dec;11(12):775-80.

PMID: 4448540

Matched MeSH terms: Anemia, Hypochromic/epidemiology

Fulltext Prevalence of 3.7 and 4.2 deletions in Sudanese patients with red cells hypochromia and microcytosis

Osman HA, Hamid MMA, Ahmad RB, Saleem M, Abdallah SA

BMC Res Notes, 2020 Feb 10;13(1):65.

PMID: 32041645 DOI: 10.1186/s13104-020-4933-5

OBJECTIVE: Alpha-thalassemia is a genetic disorder characterized by deletions of one or more α globin genes that result in deficient of α globin chains reducing haemoglobin concentration. The study aimed to screen 97 patients with microcytosis and hypochromasia for the 3.7 and 4.2 alpha thalassemia deletion mutations.

RESULTS: Out of 97 patients screened, only 7 were carriers for the 3.7 deletion and all patients were negative for the 4.2 deletion. The 3.7 deletion was found in Foor, Hawsa and Rezagat Sudanese tribes. In the carriers of the 3.7 deletion, Red Blood Cells and Haematocrit were significantly increased. The Red Blood Cells were 7.23 ± 0.78 × 1012/L in adult males and 7.21 ± 0.67 × 1012/L in adult females while in children were 5.07 ± 0.87 × 1012/L. The mean cell volume and mean cell haemoglobin were significantly decreased, but the mean cell haemoglobin concentration slightly decreased. Haemoglobin levels didn't revealed statistically significant decrease in adult males (11.7 ± 0.57 g/dL) and adult females (11.25 ± 0.64 g/dL), while in children were (11.6 ± 2.95 g/dL). Haemoglobin electrophoresis revealed two patients of the 3.7 and 4.2 negative were carriers for β-thalassemia. The study concluded that α3.7 deletion has frequency of 0.07 in Sudanese with hypochromasia and microcytosis.

Matched MeSH terms: Anemia, Hypochromic/epidemiology

Anaemia and folate status in late pregnancy in a mixed Asiatic population

Hibbard BM, Hibbard ED

J Obstet Gynaecol Br Commonw, 1972 Jul;79(7):584-91.

PMID: 5043421

Matched MeSH terms: Anemia, Hypochromic/epidemiology

Iron deficiency in the tropics

Fleming AF

Clin Haematol, 1982 Jun;11(2):365-88.

PMID: 7042157

Matched MeSH terms: Anemia, Hypochromic/epidemiology*

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