Displaying all 11 publications

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  1. Tan YO
    Family Practitioner, 1985;8(3):30-34.
    Matched MeSH terms: Anemia, Macrocytic*
  2. Pallister RA
    Matched MeSH terms: Anemia, Macrocytic
  3. Llewellynjones D
    Aust N Z J Obstet Gynaecol, 1965 Nov;5(4):191-7.
    PMID: 5215888
    Matched MeSH terms: Anemia, Macrocytic*
  4. Dutt KA, Velathaun T
    Med J Malaya, 1971 Sep;26(1):65-7.
    PMID: 4258580
    Matched MeSH terms: Anemia, Macrocytic/epidemiology*
  5. Norasyikin AW, Rozita M, Mohd Johan MJ, Suehazlyn Z
    Med Princ Pract, 2014;23(4):387-9.
    PMID: 24401542 DOI: 10.1159/000357645
    OBJECTIVE: To report an uncommon presentation of a rare case of autoimmune polyglandular syndrome type IIIb in an elderly woman.
    CLINICAL PRESENTATION AND INTERVENTION: A 62-year-old woman presented with anaemic symptoms and jaundice. Blood tests showed macrocytic anaemia due to vitamin B12 deficiency with Coombs negative haemolysis. A thyroid function test was consistent with hypothyroidism. Autoimmune antibody assays were positive for anti-parietal cell, anti-intrinsic factor and anti-thyroid peroxidase antibodies. A final diagnosis of autoimmune thyroiditis with pernicious anaemia, which constituted autoimmune polyglandular syndrome type IIIb, was made and the patient was treated with L-thyroxine, vitamin B12 injection and a blood transfusion. She was discharged uneventfully after a week of hospitalization.
    CONCLUSION: This case showed that the presence of one autoimmune endocrine disease should prompt clinicians to look for other coexisting autoimmune diseases which may be asymptomatic despite positive autoantibodies.
    Matched MeSH terms: Anemia, Macrocytic/physiopathology
  6. ENG LL, DEWITT G
    Med J Malaysia, 1964 Jun;18:269-75.
    PMID: 14199445
    Matched MeSH terms: Anemia, Macrocytic*
  7. Ong HC
    J Trop Med Hyg, 1974 Jan;77(1):22-6.
    PMID: 4811560
    Matched MeSH terms: Anemia, Macrocytic/epidemiology
  8. Shmukler BE, Kedar PS, Warang P, Desai M, Madkaikar M, Ghosh K, et al.
    Am J Hematol, 2010 Oct;85(10):824-8.
    PMID: 20799361 DOI: 10.1002/ajh.21836
    Familial distal renal tubular acidosis (dRTA) can be caused by mutations in the Cl2/HCO32 exchanger of the renal Type A intercalated cell, kidney AE1/SLC4A1. dRTA-associated AE1 mutations have been reported in families from North America, Europe, Thailand, Malaysia, Papua-New Guinea, Taiwan, and the Philippines, but not India. The dRTA mutation AE1 A858D has been detected only in the context of compound heterozygosity. We report here two unrelated Indian patients with combined hemolytic anemia and dRTA who share homozygous A858D mutations of the AE1/SLC4A1 gene. The mutation creates a novel restriction site that is validated for diagnostic screening.
    Matched MeSH terms: Anemia, Macrocytic/complications; Anemia, Macrocytic/drug therapy
  9. Hibbard BM, Hibbard ED
    J Obstet Gynaecol Br Commonw, 1972 Jul;79(7):584-91.
    PMID: 5043421
    Matched MeSH terms: Anemia, Macrocytic/epidemiology
  10. Lee KT, Teoh CS, Chew TK, Goh AS
    J R Coll Physicians Edinb, 2020 Jun;50(2):144-147.
    PMID: 32568285 DOI: 10.4997/JRCPE.2020.213
    Vitamin B12 deficiency and folate deficiency are common causes of macrocytic anaemia and both are important for many cellular processes. These deficiencies could be due to inadequate dietary intake, impaired absorption or drug ingestion. We present a case of a 47-year-old male with a history of diffuse large B-cell lymphoma (DLBCL) who was admitted for fatigue, persistent frontal headache and left upper-quadrant abdominal pain. Further investigation showed that he had pancytopenia with microangiopathic haemolytic anaemia (MAHA) and intracranial bleeding (ICB). Serum vitamin B12 and folate were later found to be low and a diagnosis of combined vitamin B12 and folate deficiency mimicking thrombotic thrombocytopenic purpura (TTP) was made. The patient responded well to vitamin B12 and folate replacement.
    Matched MeSH terms: Anemia, Macrocytic
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