MyMedR

OBJECTIVE: The objective of this study was to map evidence of the association of ABO blood groups with allergic diseases such as allergic rhinitis (AR), atopic dermatitis (AD) and asthma.

DESIGN: A scoping review.

DATA SOURCES: PubMed, Scopus, Direct Open Access Journal, Medline, Cumulative Index to Nursing and Allied Health Literature, ScienceDirect and SpringerLink were searched from October 2017 until May 2018.

ELIGIBILITY CRITERIA FOR SELECTING STUDIES: We selected all types of studies including case-control studies, prospective or retrospective cohort studies, cross-sectional studies and experimental studies, and we included reviews such as literature reviews, systematic reviews with or without meta-analysis and scoping reviews that were published in English and associated the ABO blood group with the three allergic diseases (asthma, AR and AD) in humans of all age groups.

DATA EXTRACTION AND SYNTHESIS: Two reviewers independently screened the titles and abstracts and assessed the full-text articles of the abstracts that met the eligibility requirements. Data from the included studies were extracted, evaluated and reported in the form of narrative synthesis.

RESULTS: Of the 10 246 retrieved titles, only 14 articles were selected for a scoping review based on the eligibility criteria. The majority of the studies demonstrated a significant association between ABO blood groups and allergic diseases. We found that blood group O is prominent in patients with AR and asthma, while a non-O blood group is common in patients with AD.

CONCLUSION: This scoping review serves as preliminary evidence for the association of ABO blood groups with allergic diseases. Further studies need to be conducted so that the relationship between ABO blood groups and allergic diseases can be fully established. This could be helpful for clinicians and health professionals in consulting and managing patients who suffer from allergic diseases in the future.

Matched MeSH terms: Blood Group Antigens/blood*; Hypersensitivity, Immediate/blood*

AN INVESTIGATION INTO THE COMMON CAUSES OF BLOODSTAIN DETERIORATION.I

SINGH S, KHUAN OY

Med J Malaysia, 1964 Jun;18:251-61.

PMID: 14199443

Matched MeSH terms: Blood Chemical Analysis*; Blood Group Antigens*; Blood Stains*

Fulltext Assessment of quality of platelets preserved in plasma and platelet additive solution: A Malaysian experience

Mokhtar MB, Hashim HB, Joshi SR

Asian J Transfus Sci, 2016 Jan-Jun;10(1):84-7.

PMID: 27011678 DOI: 10.4103/0973-6247.172177

A use of platelet additives solution (PAS) improves storage conditions so as to give increased shelf life to platelets and to maintain hemostatic function.

Matched MeSH terms: Blood Platelets; Blood Preservation

AN INVESTIGATION INTO THE COMMON CAUSES OF BLOODSTAIN DETERIORATION. II. EFFECT OF PERSPIRATION AND SALIVA ON BLOOD GROUPING

SINGH S, KUNG TT

Med J Malaysia, 1964 Jun;18:262-8.

PMID: 14199444

Matched MeSH terms: Blood Chemical Analysis*; Blood Grouping and Crossmatching*; Blood Group Antigens*; Blood Stains*

Evaluation of dextrostix in blood sugar estimation

Buttery JE, de Witt GF, Ahmad UO

Med J Malaya, 1967 Jun;21(4):362-5.

PMID: 4230505

Matched MeSH terms: Blood Glucose/analysis*

Fulltext Serum alpha-i acid glycoprotein in thyroid dysfunctions

Ho CL, Cheah JS

Med J Malaysia, 1982 Mar;37(1):70-1.

PMID: 7121352

The serum alpha-1 acid glycoprotein of 9 euthyroid subjects, 14 hypothyroid patients and 21 hyperthyroid patients was determined by radial immunodiffussion in agar plates. The serum alpha1 acid glycoprotein level in both the hypothyroid and hyperthyroid patients were significantly lowered when compared to the euthyroid subjects. There was no significant correlation between the alpha-1 acid glycoprotein level mid the Liothyronine resin uptake (T3 resin. uptake) and the serum total Thyroxine Iodide (T4I) level.

Matched MeSH terms: Hyperthyroidism/blood; Hypothyroidism/blood; Thyroid Diseases/blood*

Fulltext In Vitro Cell Proliferation and Migration Properties of Oral Mucosal Fibroblasts: A Comparative Study on the Effects of Cord Blood- and Peripheral Blood-Platelet Lysate

Azmi AF, Yahya MAAM, Azhar NA, Ibrahim N, Ghafar NA, Ghani NAA, et al.

Int J Mol Sci, 2023 Mar 17;24(6).

PMID: 36982842 DOI: 10.3390/ijms24065775

Cord blood-platelet lysate (CB-PL), containing growth factors such as a platelet-derived growth factor, has a similar efficacy to peripheral blood-platelet lysate (PB-PL) in initiating cell growth and differentiation, which makes it a unique alternative to be implemented into oral ulceration healing. This research study aimed to compare the effectiveness of CB-PL and PB-PL in promoting oral wound closure in vitro. Alamar blue assay was used to determine the optimal concentration of CB-PL and PB-PL in enhancing the proliferation of human oral mucosal fibroblasts (HOMF). The percentage of wound closure was measured using the wound-healing assay for CB-PL and PB-PL at the optimal concentration of 1.25% and 0.3125%, respectively. The gene expressions of cell phenotypic makers (Col. I, Col. III, elastin and fibronectin) were determined via qRT-PCR. The concentrations of PDGF-BB were quantified using ELISA. We found that CB-PL was as effective as PB-PL in promoting wound-healing and both PL were more effective compared to the control (CTRL) group in accelerating the cell migration in the wound-healing assay. The gene expressions of Col. III and fibronectin were significantly higher in PB-PL compared to CB-PL. The PDGF-BB concentration of PB-PL was the highest and it decreased after the wound closed on day 3. Therefore, we concluded that PL from both sources can be a beneficial treatment for wound-healing, but PB-PL showed the most promising wound-healing properties in this study.

Matched MeSH terms: Blood Platelets/metabolism; Fetal Blood*

Fulltext Office blood pressure measurement: A comprehensive review

Siddique S, Hameed Khan A, Shahab H, Zhang YQ, Chin Tay J, Buranakitjaroen P, et al.

J Clin Hypertens (Greenwich), 2021 03;23(3):440-449.

PMID: 33420745 DOI: 10.1111/jch.14169

The conventional auscultatory methods for measuring blood pressure have been used to screen, diagnose, and manage hypertension since long. However, these have been found to be prone to errors especially the white coat phenomena which cause falsely high blood pressure readings. The Mercury sphygmomanometer and the Aneroid variety are no longer recommended by WHO for varying reasons. The Oscillometric devices are now recommended with preference for the Automated Office Blood Pressure measurement device which was found to have readings nearest to the Awake Ambulatory Blood Pressure readings. The downside for this device is the cost barrier. The alternative is to use the simple oscillometric device, which is much cheaper, with the rest and isolation criteria of the SPRINT study. This too may be difficult due to space constraints and the post-clinic blood measurement is a new concept worth further exploration.

Matched MeSH terms: Blood Pressure; Blood Pressure Determination; Blood Pressure Monitoring, Ambulatory*

The role of peripheral blood smear examination in the evaluation of suspected platelet-related disorders in children: A practical approach and an illustrated review

Tyrrell L, Scruggs M, Kerwin A, Kahwash SB

Malays J Pathol, 2022 Dec;44(3):397-413.

PMID: 36591709

Platelets, along with coagulation factors and vasculature, represent the three main compartments of hemostasis. Upon investigation of a suspected hemostasis disorder, platelet count, size and morphology often offer important clues to the diagnosis or help narrow the differential diagnosis. In this review, we describe a general approach to diagnosing platelet disorders, starting with easily obtained data such as findings of complete blood count (CBC) and microscopic review of a stained peripheral blood smear. We discuss general findings that help separate consumptive from underproduction thrombocytopenia. We further touch on inherited thrombocytopenia disorders after classifying them into those associated with small, normal sized or large platelets. Illustrative microscopic images are provided where contributory. We conclude with a suggested algorithmic step-by-step approach to investigating a suspected platelet disorder in children.

Matched MeSH terms: Blood Coagulation Disorders*; Blood Platelets

Normotensive Primary Aldosteronism - Does it Exist?

Loh HH, Sukor N

Horm Metab Res, 2025 Mar;57(3):149-155.

PMID: 40049223 DOI: 10.1055/a-2530-1792

Heightened aldosterone levels are associated with increased risk of renal sequelae, cardiovascular morbidity and mortality. Historically, primary aldosteronism is linked to hypertension. However, growing evidence reveals its presence even in normotensive individuals. This review consolidates data from diverse sources, delves into clinical studies of this underexplored condition, discusses the potential mechanisms, and provides a comprehensive and an up-to-date overview of the current state of knowledge. It highlights the evidence and understanding of normotensive primary aldosteronism, summarizes findings, and identifies opportunities for future research in this area. By addressing the clinical evidence, risk of hypertension development and possible mechanisms involved, this review aims to advance the understanding of this distinct form of primary aldosteronism and inspire further research in this emerging field.

Matched MeSH terms: Aldosterone/blood; Blood Pressure

Response: importance of screening for macroprolactin in hyperprolactinaemic sera

Jamaluddin FA

Malays J Pathol, 2013 Dec;35(2):190.

PMID: 24362487

Matched MeSH terms: Blood Chemical Analysis/methods*; Hyperprolactinemia/blood*; Prolactin/blood*

Fulltext Comparing measured total carbon dioxide and calculated bicarbonate

Nasir NM, Sthaneshwar P, Yunus PJ, Yap SF

Malays J Pathol, 2010 Jun;32(1):21-6.

PMID: 20614722 MyJurnal

The objective of the study is to determine the level of agreement between measured total carbon dioxide (TCO2) and calculated bicarbonate (HCO3-) in our laboratory.

Matched MeSH terms: Bicarbonates/blood*; Blood Gas Analysis/methods; Carbon Dioxide/blood*

Blood cholinesterase levels in the elderly and newborn

Chan L

Malays J Pathol, 1995 Dec;17(2):87-9.

PMID: 8935132

The spectrophotometric method of Ellman was used to determine cholinesterase (ChE) levels in plasma and whole blood in elderly patients and umbilical cord blood of newborn infants. The mean +/- SD for plasma and whole blood ChE levels were 2.24 +/- 0.58 micromol/min/ml and 4.38 +/- 0.65 micromol/min/ml respectively in a group of healthy elderly patients (n = 25). The mean +/- SD for plasma and whole blood ChE levels were 2.23 +/- 0.77 and 3.31 +/- 0.56 respectively in cord blood of healthy full term newborn infants (n = 25). In a group of healthy adult blood donors the general mean +/- SD for plasma and whole blood ChE have been shown to be 2.71 +/- 0.75 and 4.87 +/- 0.73 micromol/min/ml respectively. Statistical analysis revealed that the mean levels of plasma and whole blood ChE in elderly, newborn infants and adults were different (p < 0.001). However, there was no statistical difference between the mean level of plasma ChE in elderly and cord blood but each shared statistically significant difference when compared to the mean level in adults. The mean activity of whole blood ChE in the 3 groups was different from one another. Theoretically, decreased levels of ChE would suggest a careful assessment of drugs that are hydrolysed by ChE.

Matched MeSH terms: Aging/blood*; Cholinesterases/blood*; Fetal Blood/enzymology*

Fulltext Blood transfusion services amidst the COVID-19 pandemic

Noordin SS, Yusoff NM, Karim FA, Chong SE

J Glob Health, 2021 Apr 17;11:03053.

PMID: 33884188 DOI: 10.7189/jogh.11.03053

Matched MeSH terms: Blood Banks/supply & distribution*; Blood Banks/trends; Blood Donors/supply & distribution*

Fulltext The Effects of High-Intensity Interval Training on Cardiometabolic Health in Children and Adolescents: A Systematic Review and Meta-Analysis

Song Y, Lan H

J Sports Sci Med, 2024 Dec;23(4):690-706.

PMID: 39649559 DOI: 10.52082/jssm.2024.690

High-intensity interval training (HIIT) interventions are typically prescribed according to several laboratory-based parameters and fixed reference intensities to accurately calibrate exercise intensity. Repeated all-out printing efforts, or sprint interval training, is another form of HIIT that is prescribed without individual reference intensity as it is performed in maximal intensities. No previous study has performed a systematic review and meta-analysis to investigate the effect of HIIT and SIT on cardiometabolic health markers in children and adolescents. Moreover, previous studies have focused on single risk factors and exercise modalities, which may restrict their ability to capture a complete picture of the factors that could be affected by different interval interventions. The present study aimed to conduct a novel meta-analysis on the effects of HIIT and SIT on multiple cardiometabolic health markers in children and adolescents. An electronic search was conducted in three main online databases including PubMed, Web of Science, and Scopus were searched from inception to July 2024 to identify randomized and non-randomized control trials comparing HIIT and SIT versus the non-exercise control group in children and adolescents with mean age ranges from 6 to 18 years old on cardiometabolic health markers including fasting glucose and insulin, insulin resistance, triglyceride (TG), total cholesterol (TC), low-density lipoprotein cholesterol (LDL), high-density lipoprotein cholesterol (HDL), systolic blood (SBP) and diastolic blood (DBP) pressures. Standardized mean differences (SMD), weighted mean differences (WMD), and confidence were calculated using a random effect model. HIIT decreased insulin, insulin resistance, TG, TC, LDL, and SBP and increased HDL but did not decrease glucose and DBP. Furthermore, subgroup analyses show that insulin and insulin resistance were decreased by sprint interval training (SIT) and in those with obesity. Lipid profile mainly is improved by SIT and in those with obesity. Also, SBP was decreased by SIT and in those with obesity. Our results prove that HIIT is an effective intervention for improving cardiometabolic health in children and adolescents, mainly those with obesity. Specifically, SIT is an effective interval training mode in children and adolescents.

Matched MeSH terms: Blood Pressure; Lipids/blood; Triglycerides/blood; Biomarkers/blood

Fulltext The relationships between thyroid hormones and thyroid-stimulating hormone with lipid profile in euthyroid men

Chin KY, Ima-Nirwana S, Mohamed IN, Aminuddin A, Johari MH, Ngah WZ

Int J Med Sci, 2014;11(4):349-55.

PMID: 24578612 DOI: 10.7150/ijms.7104

Alteration in lipid profile is a common observation in patients with thyroid dysfunction, but the current knowledge on the relationship between lipids and thyroid hormone levels in euthyroid state is insufficient. The current study aimed to determine the association between thyroid hormones and thyroid-stimulating hormone (TSH) with lipid profile in a euthyroid male population.

Matched MeSH terms: Cholesterol/blood; Lipids/blood*; Cholesterol, HDL/blood; Cholesterol, LDL/blood; Thyroid Hormones/blood*; Thyrotropin/blood*; Thyroxine/blood; Triglycerides/blood; Triiodothyronine/blood

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