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  1. Shaharuddin NR, Leong CL, Chidambaram SK, Lee C
    Med J Malaysia, 2012 Jun;67(3):337-9.
    PMID: 23082432
    Paraspinal abscess and spondylodiscitis due to Citrobacter koseri is a very rare condition. We report a remarkable case of Citrobacter koseri bacteraemia complicated by paraspinal abscess and spondylodiscitis in a patient who has successfully been treated in our hospital. Our patient demonstrates one of the common challenges in the practice of infectious disease medicine, wherein an innocuous presentation may and often underlie a serious infection. This case report elucidates to us that the diagnosis of a paraspinal abscess and spondylodiscitis requires a high index of suspicion in at risk patient presenting with compatible signs and symptoms.
    Matched MeSH terms: Discitis/complications; Discitis/drug therapy; Discitis/microbiology*
  2. Muhamad Effendi F, Ibrahim MI, Mohd Miswan MF
    BMJ Case Rep, 2016 Jul 05;2016.
    PMID: 27381996 DOI: 10.1136/bcr-2016-215909
    Extraintestinal Salmonella infection involving the thoracic spine is very rare. It commonly presents with non-specific chronic back pain and can occur with no gastrointestinal manifestation. Blood test results and imaging findings are often indistinguishable from more common chronic spine infections such as spine tuberculosis. Culture studies remain the key to establishing a definitive diagnosis and subsequently successful treatment. We report a case in which a patient presented with symptoms and signs suggestive of spine tuberculosis, yet the culture examination revealed otherwise.
    Matched MeSH terms: Discitis/diagnosis*; Discitis/drug therapy; Discitis/microbiology*
  3. Tai, Sharon Mei-Ling, Hazman Mohd Nor, Kartini Rahmat, Pow, Zhen Yuan, Ong, Lay Sim, Tan, Chong Tin, et al.
    Neurology Asia, 2017;22(4):313-323.
    MyJurnal
    Background: Tuberculous disease of spine (spinal TB) is under-recognized in tuberculous (TB) meningitis.
    The objective of the study was to evaluate the frequency, clinical and neuroimaging changes, and
    outcome in the patients with spinal TB.

    Methods: All the patients with spinal TB admitted in the two
    largest tertiary hospitals in Kuala Lumpur from 2009 to 2017 were recruited, the clinical features were
    documented, the magnetic resonance imaging (MRI) of the spine was performed. Clinical outcome was
    assessed with Modified Rankin scale (MRS).

    Results: Twenty two patients were recruited. This was
    out of 70 TB meningitis patients (31.4%) seen over the same period. Eighteen (81.8%) patients had
    concomitant TB meningitis. The clinical features consisted of systemic symptoms with fever (63.6%),
    meningitis symptoms with altered sensorium (45.5%), myelopathy with paraparesis (36.4%). The
    findings on spinal MRI were discitis (36.4%), spinal meningeal enhancement (31.8%), spinal cord
    compression (31.8%), psoas abscess (27.3%), osteomyelitis (22.7%), and cord oedema (22.7%). All
    except two patients (90.9%) had involvement in psoas muscle, bone or leptomeningeal enhancement,
    features that can be used to differentiate from myelopathy that affect the parenchyma only, such as
    demyelination. Unusual manifestations were syringomyelia and paradoxical manifestations seen in 3
    patients each. The outcome were overall poor, with 68% having MRS 3 or more.

    Conclusion: Spinal TB is common in TB meningitis. The outcome is overall poor. A heightened
    awareness is crucial to enable early diagnosis and treatment.
    Matched MeSH terms: Discitis
  4. Ariffin MHM, Ibrahim K, Baharudin A, Tamil AM
    Asian Spine J, 2019 Oct 15.
    PMID: 31608611 DOI: 10.31616/asj.2019.0075
    Study Design: Prospective observational study (n=74).

    Purpose: To evaluate the learning curve for exoscope and three-dimensional (3D) 4K hybrid visualization in terms of operating time, advantages, disadvantages, and surgical complications in tubular-access minimally invasive spine surgery (MISS) and to assess surgeon satisfaction with image quality, ergonomics, and ability to perform target site treatment.

    Overview of Literature: Working through tubular retractors poses a challenge. The extreme angulations during microsurgical decompression, especially contralateral decompression, require surgeons to work non-ergonomically. An exoscope allows surgeons to work ergonomically and independently of the microscope oculars as visualizations are now provided by large 3D 4K monitors. However, the value and efficacy of solely depending on an exoscope and 3D 4K monitors during microsurgical work are still unknown.

    Methods: Seventy-four patients (99 levels) underwent trans-tubular MISS between March 2018 and January 2019. Five patients were excluded: one had pyogenic discitis, two had revisions, and two were trans-tubular transoral. In total, we analyzed 69 for operating time, blood loss, and complications. The learning curve graph was plotted using the surgical time for each procedure. Surgeons were asked to rate their satisfaction with image quality, ability to maintain ergonomic posture, and efficient target site treatment.

    Results: For tubular microdiscectomy, the operating time plateaued after six cases, and for tubular decompression and minimally invasive transforaminal lumbar interbody fusion, the operating time plateaued after nine cases. Mean operating time was significantly reduced after the plateau. Complications included four cases of dural tear. All patients improved symptomatically, and there were no postoperative neurological deficits.

    Conclusions: Use of the exoscope has a short learning curve. Surgeons benefit from improved ergonomic posture during surgery, and resident teaching appears to be good. The only drawback is the need to rearrange the operating table setup. Complications were comparable to those when using the surgical microscope. An exoscope with hybrid digital visualization provides excellent visualization, depth perception, clarity, and precision target site treatment.

    Matched MeSH terms: Discitis
  5. Ahmedy F, Ahmad Fauzi A, Engkasan JP
    PMID: 29844926 DOI: 10.1038/s41394-018-0074-7
    Introduction: Tachycardia, or elevated heart rate is one of the important clinical parameters considered when diagnosing pulmonary embolism (PE) based on Wells' criteria. However, tachycardia is not highly specific and commonly presents in many other conditions.

    Case presentation: A 29-year-old female with incomplete paraplegia secondary to tuberculosis (TB) spondylodiscitis presented with asymptomatic sinus tachycardia. The related medical conditions, including anaemia, acute coronary syndrome, hyperthyroidism and other infective causes had been ruled out. Deep venous thrombosis was not on the list of differentials as she showed improvements in neurological and mobility functions with no clinical signs of calf pain or swelling. She had moderate risk of acute PE based on Wells' criteria with positive D-dimer testing and computed tomography pulmonary angiography (CTPA) showing thrombus formation in the left-ascending pulmonary artery.

    Discussion: Acute PE may present solely with asymptomatic sinus tachycardia in TB spondylodiscitis. This caveat should provide a high index of suspicion to prevent delay in diagnosis and prevention of more sinister complications. Early stratification based on Wells' criteria for a possible diagnosis of acute PE is proven to be a useful approach in conjunction with clinical features.

    Matched MeSH terms: Discitis
  6. Lim SW, Lim HY, Kannaiah T, Zuki Z
    Malays Orthop J, 2017 Nov;11(3):50-52.
    PMID: 29326768 MyJurnal DOI: 10.5704/MOJ.1711.004
    Streptococcus constellatus is an extremely rare cause of pyogenic spondylodiscitis. Literature search yielded only one case report in an elderly 72 years old man with spontaneous T10-T11 S. constellatus spondylodiscitis. It is virtually unheard of in young teenage. We report the case of a 14 years old male teenager who presented with worsening low back pain for one year with no neurological deficit. Imaging studies were consistent with features of L4-L5 spondylodiscitis. CT guided biopsy grew a pure culture of streptococcus constellatus sensitive to penicillin and erythromycin. He showed full recovery with six weeks of intravenous antibiotics. Due to the insidious onset, this case highlight the importance of high clinical suspicion and early diagnosis, with image guided biopsy followed by treatment with appropriate intravenous antibiotics to enable full recovery without further neurological deterioration.
    Matched MeSH terms: Discitis
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