Displaying publications 1 - 20 of 80 in total

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  1. Abdul Mujid, A., Zailina, H., Juliana, J., Sharnsul Bahri, M.T.
    MyJurnal
    Satu kajian keratan rentas telah daalanlcan ke atas kanak-lcanak yang tinggal 0.5 km dari sebuah lcuari di Sungai Siput Utara. Objelctif kajian ini ialah untulc mengkaji hubungan PM10 dengan fungsi paru-paru kanak-kanak tersebut. Seramai 51 orang kanak-/canak yang ringgal berhampiran kuari dan terdedah dengan debu kaur tehih dipilih, manakala 37 orang kanak-kanak yang tinggal berjauhan tetapi di daerah yang sama telah dipilih sebagai perbandingan untuk lag ian ini. Borang soalselidik telah digunakan untuk mendapatlcan maklumat latarbelakang dan sejarah respiratori dari ibu bapa kanalc-kanak terlibat. Fungsi paru-paru kanak-kanak pula diukur dengan menggunakan Pony Graphic S pirometer. Min kepekatan PM1 0 selama 24 jam di dalam rumah kediaman di kawasan terdedah ialah 76.66 (g/m3 dan di kawasan perbandingan 41 .55 (g/m3. Perbezaan kepekatan PM10 di antara kedua kawasan ini adalah signifikan (p=0.01). Hasil ujian fungsi paru-paru menunjukkan perbezaan yang signifikan di antara fungsi paru-paru kanalc-kanalc terdedah dengan kanak-kanak perbandingan dari segi FVC % jangkaan (t = -8.227, p = 0.01) dan FEV1 % jangkaan (t = -8.729, p = 0.01). Min fungsi paru-paru kanak-kanak lelaki di kawasan terdedah, (FVC % jangkaan = 68.05, FEV1 % jangkaan = 73.71) adalah lebih rendah daripada kawasan perbandingan (FVC % jangkaan= 89.78, FEV1 %~ jangkaan = 86.97). Min fungsi paru-paru kanak-kanak perempuan di kawasan terdedah (FVC % jangkaan= 69.64, FEV1 % jangkaan =74.90) juga adalah lebih rendah daripada hawasan perbandingan ( F VC % jangkaan = 90.99, FEV1 % jangkaan : 87 .7 9). Prevalens kejejasan parurparu FVC % jangkaan l
    Matched MeSH terms: Horses
  2. Mayaki AM, Abdul Razak IS, Noraniza MA, Mazlina M, Rasedee A
    J Equine Vet Sci, 2020 03;86:102907.
    PMID: 32067661 DOI: 10.1016/j.jevs.2019.102907
    Neurological disorders (NDs) are often fatal to horses. Thus, symptoms of equine NDs commonly indicate euthanasia. Current diagnostic approaches for equine NDs is based on clinical signs, differential diagnoses, analysis of cerebrospinal fluid (CSF), assessment of histopathological lesions, and imaging. However, advances in biofluid biomarkers in the diagnosis of human neurological diseases can potentially be applied to equine NDs. In this review, we described the established human blood and CSF neurobiomarkers that could potentially be used to diagnose equine NDs.
    Matched MeSH terms: Horses
  3. Lake, S.T., Aug, L.C.
    MyJurnal
    This survey elucidated the perceptions and implementation 0f orthodontic Clinical Practice Guidelines (CPGs) by all ortlmduntistc and dental officers in the Ministry of Health Mahysia (MOH). Two different set: uf xelf-administered questionnaires were targeted at first·year dental officers (FYDO), dental officcrx (DO) and administrative Senior Dental Officers (SDO) in one group and unhocluntists in another group. Only 30% responded from a total of 1,327 MOH dental officers, with no participation from three States. Majority (89%) of officers have heard of CPG: although some were unsure of their purpose and usage. About 69% have read orthodontic CPG; of whom 87% have read other MOH dental CPG:. About 78.6% found CPGs 'gaud to excellenf but 16,0% did not answer this question. Same comments received included: language was confusing, inadequate details and pictures, need improvement, irrelevant, need CPG: for other orthodontic problems, need more knowledge first and requests for mare copies. Only 27.7% used them often, 53% occasionally and 15% hardly follow CPG:. About 82% felt that they were encouraged to use CPGx in their workplace and the majority (86%) knew where they were kept especially SDC: and DO; About 90% in the orthndonzist group have received hard copies of orthodontic CPGs but the majority (76%) has not seen them on the website. Although all felt that CPG; were useful to officers and encouraged their use, only 62.5% have introduced CPGs to their officers. There was generally more awareness and usage of CPGS among SDOs compared with DOs and FY DO; The dissemination and availability of orthodontic CPG: is reasonably good. However, the implementation by mthodontists and administrative officers can be improved for better awareness, understanding and usage by dental officers, especially FYDOs.
    Matched MeSH terms: Horses
  4. Yiew, X.T., Khairuddin, N.H., Murdoch, A.I.K., Patil, P.V., Shashi Singam, R., Koay, C.P.
    Jurnal Veterinar Malaysia, 2015;27(2):8-11.
    MyJurnal
    A six-year-old Thoroughbred race horse was presented with left unilateral mucopurulent nasal discharge. Endoscopic examination revealed atypical mycotic lesion within the guttural pouch in which the fungal mass was not located on any neurovascular structures. This case was successfully treated by the combination of manual debulking of fungal diphtheritic plaques and medical treatment that included daily local irrigation and systemic medication. There were no complications and the horse returned to race three weeks later.
    Matched MeSH terms: Horses
  5. Shaw DJ, Rosanowski SM
    Vet. J., 2019 Aug;250:24-27.
    PMID: 31383416 DOI: 10.1016/j.tvjl.2019.05.015
    Epiglottic entrapment is a condition in racing horses, associated with abnormal respiratory noises and exercise intolerance. Epiglottic entrapment has been linked to both poor and superior athletic performance, leading to concerns regarding whether surgery is indicated, and whether surgical correction may have a deleterious effect on future race performance. The objective of the current study was to assess the race-day performance of horses racing with epiglottic entrapment and the effect of surgical correction on performance outcomes using an intra-oral technique in anaesthetised horses. A case-control study was conducted at the Singapore Turf Club from 2008 to 2011. Controls were selected 1:1 to cases, based on Malaysian Racing Authority number. The performance of horses racing with epiglottic entrapment was recorded and post-surgery race performance was described. Further, post-surgery race performance was compared between cases and with non-case controls. Twenty horses raced with epiglottic entrapment were retrospectively enrolled. There was a significant difference in racing performance in case horses racing with and without epiglottic entrapment (P 
    Matched MeSH terms: Horses/physiology*; Horses/surgery
  6. Labens R, Khairuddin NH, Murray M, Jermyn K, Ahmad RS
    Vet Surg, 2019 Jan;48(1):96-104.
    PMID: 30403407 DOI: 10.1111/vsu.13123
    OBJECTIVE: To assess fracture gap reduction and stability of linear vs triangular 4.5-mm lag screw repair of experimental, uniarticular, and complete forelimb proximal phalanx (P1) fractures.

    STUDY DESIGN: Experimental.

    SAMPLE POPULATION: Fourteen equine cadaver limbs/horses.

    METHODS: Simulated fractures were repaired with 2 lag screws under 4-Nm insertion torque (linear repair). Computed tomography (CT) imaging was performed with the leg unloaded and loaded to forces generated while walking. The fracture repair was revised to include 3 lag screws placed with the same insertion torque (triangular repair) prior to CT. The width of the fracture gap was assessed qualitatively by 2 observers and graded on the basis of gap measurements relative to the average voxel size at dorsal, mid, and palmar P1 sites. Interobserver agreement was assessed with Cohen's κ. The effect of repair type, loading condition, and measurement site on fracture gap grades was evaluated by using Kendall's τ-b correlation coefficients and paired nonparametric tests. Significance was set at P ≤ .05.

    RESULTS: Agreement between loading and fracture gap widening was fair in triangular (κ = 0.53) and excellent in linear (κ = 0.81) repairs. Loading resulted in fracture gap distraction in linear repairs (Plinear  = .008). Triangular repairs reduced fractures better irrespective of loading (Punloaded  = .003; Ploaded  

    Matched MeSH terms: Horses/injuries; Horses/surgery*
  7. Asmah Rahmat, Rozita Rosli, Tan, Mui Hoon, Nasir Umar-Tsafe, Abdul Manaf Ali, Mohd Fadzelly Abu Bakar
    MyJurnal
    Objective: Previous studies have shown milk to contain cancer inhibitors. In this context, this study was conducted to screen the potential cytotoxic properties of four different types of milk, namely cow's milk, goat's milk, mare's milk and human milk.
    Methods: In evaluating the cytotoxic properties of milk, two different human leukemia cell lines namely, Raji and CEM-SS were used. The treated and untreated cells of milk were cultured at 37°C in 5% CO2 for 5 days according to standard guidelines. The CellTiter 96® Aqueous (MTS) assay was carried out on the first, third and fifth days to measure cell viability. The percentage of cell viability was determined by comparing the optical density of the treated cells against the untreated controls. One-way ANOYA at p
    Matched MeSH terms: Horses
  8. PATERSON PY, LEY HL, WISSEMAN CL, POND WL, SMADEL JE, DIERCKS FH, et al.
    Am J Hyg, 1952 Nov;56(3):320-33.
    PMID: 12996500
    Matched MeSH terms: Horses
  9. Mayaki AM, Abdul Razak IS, Adzahan NM, Mazlan M, Rasedee A
    J Vet Sci, 2020 Nov;21(6):e82.
    PMID: 33263229 DOI: 10.4142/jvs.2020.21.e82
    BACKGROUND: The clinical presentation of horses with back pain (BP) vary considerably with most horse's willingness to take part in athletic or riding purpose becoming impossible. However, there are some clinical features that are directly responsible for the loss or failure of performance.

    OBJECTIVES: To investigate the clinical features of the thoracolumbar region associated with BP in horses and to use some of the clinical features to classify equine BP.

    METHODS: Twenty-four horses comprised of 14 with BP and 10 apparently healthy horses were assessed for clinical abnormality that best differentiate BP from normal horses. The horses were then graded (0-5) using the degree of pain response, muscular hypertonicity, thoracolumbar joint stiffness and overall physical dysfunction of the horse.

    RESULTS: The common clinical features that significantly differentiate horses with BP from non-BP were longissimus dorsi spasm at palpation (78.6%), paravertebral muscle stiffness (64.3%), resist lateral bending (64.3%), and poor hindlimb impulsion (85.7%). There were significantly (p < 0.05) higher scores for pain response to palpation, muscular hypertonicity, thoracolumbar joint stiffness and physical dysfunction among horses with BP in relation to non-BP. A significant relationship exists between all the graded abnormalities. Based on the cumulative score, horses with BP were categorized into mild, mild-moderate, moderate and severe cases.

    CONCLUSIONS: BP in horse can be differentiated by severity of pain response to back palpation, back muscle hypertonicity, thoracolumbar joint stiffness, physical dysfunctions and their cumulative grading score is useful in the assessment and categorization of BP in horses.

    Matched MeSH terms: Horses
  10. Hanis F, Chung ELT, Kamalludin MH, Idrus Z
    J Equine Vet Sci, 2020 11;94:103230.
    PMID: 33077069 DOI: 10.1016/j.jevs.2020.103230
    The present study aimed to provide preliminary data on the prevalence of oral stereotypic, locomotory stereotypic, and redirected behaviors as well as their associations with stable management and feeding practices. In this cross-sectional study, a total of 207 working horses used for leisure riding, equestrian sport, polo, endurance, and patrolling were selected from seven equine facilities. Data on the stable management and feeding practices were obtained through the stable records, interviews, and on-site monitoring visits, whereas the prevalence of abnormal behaviors in the studied population was determined using the instantaneous scan sampling method. Most horses in the present study worked for more than 8 hours per week (n = 93). In addition, more horses were fed three times per day (n = 65) with different amounts of hay, concentrate, and chaff. Among the study population, oral stereotypic behaviors had the highest prevalence (n = 281; 54%), followed by redirected behavior (n = 181; 34%), and locomotory stereotypic behaviors had the lowest prevalence (n = 63; 12%). The oral stereotypic behavior was found to be significantly influenced (P < .05) by the working hours, amount of hay, and amount of concentrate. Both locomotory stereotypic and redirected behaviors were found to be influenced (P < .05) by the number of feedings per day and the amount of hay. In summary, the present study has proven that the stable management and feeding practices could influence the prevalence of different abnormal behaviors in the majority of working horses, with oral stereotypy being the most common abnormal behavior in this country.
    Matched MeSH terms: Horses
  11. Al-Majhali SH, Khairuddin NH, Abdul Razak IS, Radzi Z, Rahman MT, Sapalo JT, et al.
    J Equine Vet Sci, 2021 04;99:103399.
    PMID: 33781409 DOI: 10.1016/j.jevs.2021.103399
    The use of a self-inflating tissue expander is a technique to stretch cutaneous tissues for potential use in reconstructive skin surgeries. This study investigates the mechanical properties of horse skin stretched by the subcutaneous implantation of anisotropic tissue expanders at the forehead, right shoulder, and dorsomedial part of the cannon region of the right forelimb in six (n = 6) horses. After 14 days of skin expansion, expanded and normal (control) skin samples were harvested and their mechanical properties of elastic modulus (EM), maximum force (MF), maximum stress (MSs) and maximum strain (MSr) were evaluated using uniaxial tension test. The expanded skin from shoulder area has higher EM, MSs, MSr and MF than the normal skin when compared to the forehead and lower forelimb. Statistically, there was a significant (P= .02) mean difference for MSs between the expanded shoulder and lower forelimb skin, but the pairwise comparison of EM, MSr and MF showed no significant difference between the locations. The overall effect of locations on EM and MSs was statistically significant (P < .05), however, there was no overall effect of horse factor, treatment factor (normal and expanded skin) and location interaction on the EM, MSS, MF and MSr. In conclusion, the expanded skin from the frontal head and the distal limb are less elastic (stiffer) compared to that of the expanded skin of the shoulder, thus anatomical location of the skin has some degree of effect on EM and MSs.
    Matched MeSH terms: Horses
  12. Alamaary MS, Haron AW, Ali M, Hiew MWH, Adamu L, Peter ID
    Vet World, 2019 Jan;12(1):34-40.
    PMID: 30936651 DOI: 10.14202/vetworld.2019.34-40
    Aim: Different types of extenders have a variety of components which show the tolerance effect on sperm protection during freezing procedures. In the present study, we have examined the impact of the extenders HF-20 and Tris, which were locally manufactured, and they are competing with commercial extenders INRA Freeze® (IMV Technologies, France) and EquiPlus Freeze® (Minitube, Germany) on the quality of horses frozen semen.

    Materials and Methods: A total of 15 ejaculates from three healthy stallions were collected and cryopreserved in the same environment. Each semen sample collected was divided into four equal parts and processed. All samples were analyzed before and after freezing for motility, viability, plasma membrane integrity, and morphology. Furthermore, twenty mares were inseminated using post-thawed semen.

    Results: There were no differences observed among all extenders in all the parameters before freezing. Sperm cryopreserved using HF-20 showed better motility, viability, and plasma membrane integrity than Tris extender. The Tris extender showed the most inferior quality of post-thawed semen between all the extenders. HF-20, INRA Freeze®, and EquiPlus Freeze® extenders revealed the same capacity of semen preservation in vitro and in vivo.

    Conclusion: HF-20 extender has the same quality as INRA Freeze® and EquiPlus Freeze® that can be considered as one of the best extenders for the semen cryopreservation in horses. In contrast, Tris extender needs some degree of improvement.

    Matched MeSH terms: Horses
  13. HALE JH, WITHERINGTON DH
    J Comp Pathol, 1953 Jul;63(3):195-8.
    PMID: 13084794
    Matched MeSH terms: Horses
  14. Louis YD, Bhagooli R, Seveso D, Maggioni D, Galli P, Vai M, et al.
    Mol Ecol, 2020 11;29(22):4382-4394.
    PMID: 32967057 DOI: 10.1111/mec.15642
    Corals show spatial acclimatisation to local environment conditions. However, the various cellular mechanisms involved in local acclimatisation and variable bleaching patterns in corals remain to be thoroughly understood. In this study, the modulation of a protein implicated in cellular heat stress tolerance, the heat shock protein 70, was compared at both gene (hsp70) and protein (Hsp70) expression level in bleaching tolerant near-coast Acropora muricata colonies and bleaching susceptible reef colonies, in the lagoon of Belle Mare (Mauritius). The relative Hsp70 levels varied significantly between colonies from the two different locations, colonies having different health conditions and the year of collection. Before the bleaching event of 2016, near-coast colonies had higher basal levels of both Hsp70 gene and protein compared to reef colonies. During the bleaching event, the near-coast colonies did not bleach and had significantly higher relative levels of both Hsp70 gene and protein compared to bleached reef colonies. No significant genetic differentiation between the two studied coral populations was observed and all the colonies analysed were associated with Symbiodiniaceae of the genus Symbiodinium (Clade A) irrespective of location and sampling period. These findings provide further evidence of the involvement of Hsp70 in conferring bleaching tolerance to corals. Moreover, the consistent expression differences of Hsp70 gene and protein between the near-coast and reef coral populations in a natural setting indicate that the modulation of this Hsp is involved in local acclimatisation of corals to their environments.
    Matched MeSH terms: Horses
  15. Alamaary MS, Haron AW, Hiew MWH, Ali M
    Vet Med Sci, 2020 11;6(4):666-672.
    PMID: 32602662 DOI: 10.1002/vms3.315
    Present study aimed to investigate the effect of adding antioxidants, cysteine and ascorbic acid on the levels of glutamic oxaloacetic transaminase (GOT), glutamic-pyruvate (GPT), alkaline phosphatase (ALP), lactate dehydrogenase (LDH) and γ-glutamyl transpeptidase (GGT) enzymes of post-thawed stallion sperm. Ten ejaculates were collected each from four healthy stallions and cryopreserved using HF-20 freezing extender containing either 0 mg/ml cysteine or ascorbic acid, 0.5 mg/ml cysteine and 0.5 mg/ml ascorbic acid. All samples in freezing extender containing cysteine or ascorbic acid or none of them were assessed for sperm motility, viability, plasma membrane integrity, morphology and enzymes concentration. The ALP, LDH and GGT were significantly higher in 0-group compared with cysteine and ascorbic acid groups. The sperm motility of frozen-thawed semen with 0-group was significantly better compared with cysteine and ascorbic acid groups. The variation on viability, sperm membrane integrity and morphology were insignificant between all treated groups. Therefore, these enzymes were reduced when using antioxidants in the freezing extender. Results of the present study suggest that concentration of ALP, LDH and GGT enzymes could be used as parameters for prediction of frozen-thawed stallion semen.
    Matched MeSH terms: Horses/physiology*
  16. Selmi R, Dhibi M, Ben Said M, Ben Yahia H, Abdelaali H, Ameur H, et al.
    Trop Biomed, 2019 Sep 01;36(3):742-757.
    PMID: 33597496
    Livestock constitute habitual hosts and carriers for several infectious pathogens which may represent a serious public health concern affecting the readiness of military forces and lead to wide economic losses. The present report aimed to investigate the prevalence of some haemopathogens infecting military livestock, particularly, dromedaries, sheep and horses using Giemsa-stained blood smears. A total of 300 animals (100 from each species) were selected, clinically examined and sampled. Trypanosoma spp. (22.0%), Anaplasma spp. (17.0%) and Babesia spp. (1.0%) were identified in camels' blood. Six dromedaries were found to be co-infected by Trypanosoma and Anaplasma organisms (6.0%). Camels of female gender, infested by ticks and showing clinical signs were statistically more infected by Trypanosoma spp., compared to those of male gender, free of ticks and apparently healthy (P= 0.027, 0.000 and 0.004, respectively). Babesia spp. infection (1.0%) was identified, for the first time in Tunisia, in one adult female camel that presented abortion and anemia. Anaplasma spp. was the only haemopathogen identified in examined sheep (6.0%) and horses (17.0%). Horses infested by Hippobosca equina flies and sheep infested by Rhipicephalus turanicus ticks were more infected by Anaplasma spp. than other non-infested animals (P=0.046 and 0.042, respectively). Hyalomma dromedarii, H. impeltatum and H. excavatum were the most prevalent diagnosed ticks removed from camels with an intensity of infestation of 1.2 ticks per animal. However, in sheep, only R. turanicus was identified. H. equina and Tabanus spp. were the potential hematophagous flies found in dromedaries and horses herds. This useful data must be taken into consideration during animal treatment and vectors' control programs in Tunisian military farms which help to limit the diffusion of vector-borne diseases, keep our livestock healthy and reduce economic losses.
    Matched MeSH terms: Horses/parasitology
  17. Lee CK, Chan CY, Kwan MK
    Asian Spine J, 2015 Dec;9(6):962-5.
    PMID: 26713131 DOI: 10.4184/asj.2015.9.6.962
    Managing multiple level spinal metastases is challenging. We report the case of a 58-year-old female with advanced lung cancer who presented with multiple pathological fractures of the thoracic spine (T5, T6, T7, and T8 vertebrae). She was treated with palliative radiotherapy. Her resting pain improved, but the instability pain persisted. One month later, she had a trivial fall leading to a pathological fracture of the L2 vertebra with cauda equine syndrome. The patient was treated surgically with minimally invasive decompression of the L2 and with percutaneous instrumented stabilization using an ultra-long construct from T3 to L5 (15 spinal levels), spanning the previously radiated zone and the decompression site. Postoperatively, she had significant improvements in pain and neurology. There were no surgical complications. Ultra long construct minimally invasive spinal stabilization is the ideal approach for symptomatic multicentric spinal metastasis with poor prognostic scores. Using this technique, the goals of spinal stabilization and direct neural decompression can be achieved with minimal morbidity.
    Matched MeSH terms: Horses
  18. Khairuddin NH, Sullivan M, Pollock PJ
    Ir Vet J, 2017 04 20;70:12.
    PMID: 28439406 DOI: 10.1186/s13620-017-0090-0
    BACKGROUND: In horses, the extracranial and intracranial pathway of the internal carotid artery has been described. The extracranial pathway of the internal carotid artery begins at the carotid termination and runs on the dorsal surface of the medial compartment of the guttural pouch. Thereafter the internal carotid artery passes through the foramen lacerum to continue intracranially, forming part of the rostrolateral quadrants of the cerebral arterial circle (Circle of Willis). The objectives of this study were to define and record the anatomy of the carotid arterial tree and the internal carotid artery in donkeys using angiographic techniques. This is a prospective descriptive study on 26 cadaveric donkeys.

    METHODS: Twenty six donkey cadavers of mixed, age, sex and use presented for reasons unrelated to disease of the guttural pouch were subjected to carotid and cerebral angiography using rotational angiography. Rotational angiographic and 3 dimensional multiplanar reconstructive (3D-MPR) findings were verified with an arterial latex casting technique followed by dissection and photography.

    RESULTS: The following variations of the carotid arterial tree were identified: [1] the internal carotid and occipital arteries shared a common trunk, [2] the linguofacial trunk originated from the common carotid artery causing the common carotid artery to terminate as four branches, [3] the external carotid artery was reduced in length before giving rise to the linguofacial trunk, mimicking the appearance of the common carotid artery terminating in four branches, [4] the internal carotid artery originated at a more caudal position from the common carotid artery termination.

    CONCLUSION: Veterinarians should be aware that considerable variation exists in the carotid arterial tree of donkeys and that this variation may differ markedly from that described in the horse.

    Matched MeSH terms: Horses
  19. Shaik Alaudeen, Nor Muslim, Kamarul Faridah, Hamid Arshat
    MyJurnal
    Milk lipids play an important role in the early nutrition of an infant's life. A study was undertaken to investigate the total lipid content of milk obtained from urban, exclusively breastfeeding Malaysian mothers offill term infants. Results from approximately 600 samples analysed using a commercial kit [MerckotestO] , showed that the total lipid concentration was lowest in colostrum [1.9 + 0.1 g/dl J, however this value increased gradually with days of lactation and attained a maximum concentration of 3.1 ± 0.1 g/dl during the mature milk stage. This agrees with results from other studies that the total lipid content is indeed influenced by the stage of lactation. The effect of socioeconomic factors such as income and parity on the milk lipids was also investi-gated and the results revealed that the above factors had no significant influence on the total lipid content of Malaysian mother 's milk obtained during all three stages of lactation studied [colostrum, transitional and mature milk] . However; ethnicity showed significant influence during the mature but not in the early [colostrum and transitional] stage of lactation. This however, is not filly explained by this study. As a whole, this study suggests that the human breast, through a mechanism that is ill understood, maintains cm optimal level of total lipid in milk despite their differing cultural and genetic background. It is hoped that such scientific evidence will instil more confidence among breastfeeding mothers in this fast developing cosmopolitan nation.
    Matched MeSH terms: Horses
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