Displaying publications 1 - 20 of 6280 in total

  1. Schroeder H
    Malayan Medical Journal, 1937;12:75-83.
    Matched MeSH terms: Neoplasms
  2. Tull JC
    Matched MeSH terms: Neoplasms
  3. Mahadevan D, Sudirman A, Kandasami P, Ramesh G
    J Minim Access Surg, 2010 Oct;6(4):111-3.
    PMID: 21120068 DOI: 10.4103/0972-9941.72597
    AIM: The role of laparoscopy in staging of gastric cancer is widely accepted; however, in Malaysia its usage has been limited. Patients can be classified as resectable or unresectable, which helps in avoiding an unwanted laparotomy and the morbidities associated with it. The aim of this study was to assess the value of laparoscopy in staging of gastric cancer in comparison with CT scan.
    MATERIALS AND METHODS: Patients with carcinoma of the stomach after a complete preoperative work-up underwent laparoscopy prior to surgical exploration. TNM staging was used to compare laparoscopy with CT, with the histopathological report used as the gold standard.
    RESULTS: Forty cases were included in this study. The sensitivity of laparoscopy for T3 tumours appears to be significant when compared to that of CT. Laparoscopy detected 90.3% of the cases as against the 58% detected with CT. There was not much difference in the N factor. With regard to M factor, the sensitivity was 100% for laparoscopy in comparison with CT.
    CONCLUSIONS: Laparoscopy has been shown to be sensitive in detecting metastasis in gastric cancer in comparison to CT, thus helping in avoiding unwanted laparotomy and thus providing a more systemic approach in managing gastric cancers.
    KEYWORDS: Gastric cancer; laparoscopic staging
    Matched MeSH terms: Stomach Neoplasms*
  4. Al-Azri A
    Oman Med J, 2015 Sep;30(5):398.
    PMID: 26421125 DOI: 10.5001/omj.2015.80
    Matched MeSH terms: Nasopharyngeal Neoplasms*
  5. Koczwara B, Chan A, Jefford M, Lam WWT, Taylor C, Wakefield CE, et al.
    JCO Glob Oncol, 2023 Jan;9:e2200305.
    PMID: 36749908 DOI: 10.1200/GO.22.00305
    Matched MeSH terms: Neoplasms*
  6. Ordóñez-Mena JM, Schöttker B, Mons U, Jenab M, Freisling H, Bueno-de-Mesquita B, et al.
    BMC Med, 2016;14(1):62.
    PMID: 27044418 DOI: 10.1186/s12916-016-0607-5
    BACKGROUND: Smoking is the most important individual risk factor for many cancer sites but its association with breast and prostate cancer is not entirely clear. Rate advancement periods (RAPs) may enhance communication of smoking related risk to the general population. Thus, we estimated RAPs for the association of smoking exposure (smoking status, time since smoking cessation, smoking intensity, and duration) with total and site-specific (lung, breast, colorectal, prostate, gastric, head and neck, and pancreatic) cancer incidence and mortality.
    METHODS: This is a meta-analysis of 19 population-based prospective cohort studies with individual participant data for 897,021 European and American adults. For each cohort we calculated hazard ratios (HRs) for the association of smoking exposure with cancer outcomes using Cox regression adjusted for a common set of the most important potential confounding variables. RAPs (in years) were calculated as the ratio of the logarithms of the HRs for a given smoking exposure variable and age. Meta-analyses were employed to summarize cohort-specific HRs and RAPs.
    RESULTS: Overall, 140,205 subjects had a first incident cancer, and 53,164 died from cancer, during an average follow-up of 12 years. Current smoking advanced the overall risk of developing and dying from cancer by eight and ten years, respectively, compared with never smokers. The greatest advancements in cancer risk and mortality were seen for lung cancer and the least for breast cancer. Smoking cessation was statistically significantly associated with delays in the risk of cancer development and mortality compared with continued smoking.
    CONCLUSIONS: This investigation shows that smoking, even among older adults, considerably advances, and cessation delays, the risk of developing and dying from cancer. These findings may be helpful in more effectively communicating the harmful effects of smoking and the beneficial effect of smoking cessation.
    KEYWORDS: Cancer; Cohort; Incidence; Meta-analysis; Mortality; Smoking
    Matched MeSH terms: Neoplasms*
  7. Hoops AL
    Matched MeSH terms: Neoplasms; Pancreatic Neoplasms
    Med J Malaya, 1955 Dec;10(2):126-56.
    PMID: 13308615
    Matched MeSH terms: Nasopharyngeal Neoplasms*
  9. Tan D, Mohd Nasir NF, Abdul Manan H, Yahya N
    Cancer Radiother, 2023 Sep;27(5):398-406.
    PMID: 37482464 DOI: 10.1016/j.canrad.2023.05.001
    PURPOSE: This study aims to perform a comprehensive systematic review of deep learning (DL) models in predicting RT-induced toxicity.

    MATERIALS AND METHODS: A literature review was performed following the PRISMA guidelines. Systematic searches were performed in PubMed, Scopus, Cochrane and Embase databases from the earliest record up to September 2022. Related studies on deep learning models for radiotherapy toxicity prediction were selected based on predefined PICOS criteria.

    RESULTS: Fourteen studies of radiotherapy-treated patients on different types of cancer [prostate (n=2), HNC (n=4), liver (n=2), lung (n=4), cervical (n=1), and oesophagus (n=1)] were eligible for inclusion in the systematic review. Information regarding patient characteristics and model development was summarized. Several approaches, such as ensemble learning, data augmentation, and transfer learning, that were utilized by selected studies were discussed.

    CONCLUSION: Deep learning techniques are able to produce a consistent performance for toxicity prediction. Future research using large and diverse datasets and standardization of the study methodologies are required to improve the consistency of the research output.

    Matched MeSH terms: Neoplasms*
  10. Adlan A
    Family Practitioner, 1985;8:39-42.
    Matched MeSH terms: Neoplasms
  11. Tan TH, Boey CY, Lee BN
    Asia Ocean J Nucl Med Biol, 2016;4(2):59-65.
    PMID: 27408893 DOI: 10.7508/aojnmb.2016.02.001
    The present study aimed to evaluate the role of pre-therapeutic (18)fluorine-fluorodeoxyglucose positron emission tomography-computed tomography ((18)F-FDG PET-CT) and maximum standardized uptake value (SUVmax) in guiding the treatment strategy and predicting the prognosis of esophageal carcinoma, using the survival data of the patients.
    Matched MeSH terms: Esophageal Neoplasms
  12. Hatta W, Tong D, Lee YY, Ichihara S, Uedo N, Gotoda T
    Dig Endosc, 2017 Apr;29 Suppl 2:18-25.
    PMID: 28425657 DOI: 10.1111/den.12808
    Esophagogastric junction (EGJ) adenocarcinoma has been on the increase in Western countries. However, in Asian countries, data on the incidence of EGJ adenocarcinoma are evidently lacking. In the present review, we focus on the current clinical situation of EGJ adenocarcinoma in three Asian countries: Japan, Hong Kong, and Malaysia. The incidence of EGJ adenocarcinoma has been reported to be gradually increasing in Malaysia and Japan, whereas it has stabilized in Hong Kong. However, the number of cases in these countries is comparatively low compared with Western countries. A reason for the reported difference in the incidence and time trend of EGJ adenocarcinoma among the three countries may be explained by two distinct etiologies: one arising from chronic gastritis similar to distal gastric cancer, and the other related to gastroesophageal reflux disease similar to esophageal adenocarcinoma including Barrett's adenocarcinoma. This review also shows that there are several concerns in clinical practice for EGJ adenocarcinoma. In Hong Kong and Malaysia, many EGJ adenocarcinomas have been detected at a stage not amenable to endoscopic resection. In Japan, histological curability criteria for endoscopic resection cases have not been established. We suggest that an international collaborative study using the same definition of EGJ adenocarcinoma may be helpful not only for clarifying the characteristics of these cancers but also for improving the clinical outcome of these patients.
    Matched MeSH terms: Esophageal Neoplasms
  13. Uedo N, Yoshio T, Yoshinaga S, Takeuchi M, Hatta W, Yano T, et al.
    Dig Endosc, 2017 Apr;29 Suppl 2:26-36.
    PMID: 28425653 DOI: 10.1111/den.12849
    BACKGROUND AND AIM: Western studies have suggested two distinct etiologies of esophagogastric junction (EGJ) cancer: Helicobacter pylori-associated atrophic gastritis and non-atrophic gastric mucosa resembling esophageal adenocarcinoma. The present study investigated whether endoscopic gastric mucosal atrophy can distinguish between these two types of EGJ adenocarcinoma.

    METHODS: Data were collected from patients with Siewert type II, T1 EGJ adenocarcinoma who underwent endoscopic or surgical resection at eight Japanese institutions in 2010-2015. Clinicopathological characteristics of EGJ cancers with and without endoscopic gastric mucosal atrophy were compared. EGJ was defined as the lower end of the palisade vein and/or the top of the gastric folds.

    RESULTS: Of the 229 patients identified, 161 had endoscopic gastric mucosal atrophy and 68 did not. The latter group was younger (64 vs 70 years, P = 0.000); had a higher proportion of patients negative for H. pylori (90% vs 47%, P 
    Matched MeSH terms: Esophageal Neoplasms
    Med J Malaya, 1960 Mar;14:166-76.
    PMID: 13785569
    Matched MeSH terms: Liver Neoplasms/therapy*; Neoplasms*
  15. Hoe, Tuck Sang
    Primary malignant epithelial liver tumours in childhood are rare tumours and used to be associated with poor survival. A review of the various current modalities of treatment is undertaken.
    Matched MeSH terms: Liver Neoplasms
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