MyMedR

AIM: The role of laparoscopy in staging of gastric cancer is widely accepted; however, in Malaysia its usage has been limited. Patients can be classified as resectable or unresectable, which helps in avoiding an unwanted laparotomy and the morbidities associated with it. The aim of this study was to assess the value of laparoscopy in staging of gastric cancer in comparison with CT scan.
MATERIALS AND METHODS: Patients with carcinoma of the stomach after a complete preoperative work-up underwent laparoscopy prior to surgical exploration. TNM staging was used to compare laparoscopy with CT, with the histopathological report used as the gold standard.
RESULTS: Forty cases were included in this study. The sensitivity of laparoscopy for T3 tumours appears to be significant when compared to that of CT. Laparoscopy detected 90.3% of the cases as against the 58% detected with CT. There was not much difference in the N factor. With regard to M factor, the sensitivity was 100% for laparoscopy in comparison with CT.
CONCLUSIONS: Laparoscopy has been shown to be sensitive in detecting metastasis in gastric cancer in comparison to CT, thus helping in avoiding unwanted laparotomy and thus providing a more systemic approach in managing gastric cancers.
KEYWORDS: Gastric cancer; laparoscopic staging

Matched MeSH terms: Stomach Neoplasms*

Fulltext Letter in Reply: Comparing Nasopharyngeal Carcinoma in Oman and Malaysia

Al-Azri A

Oman Med J, 2015 Sep;30(5):398.

PMID: 26421125 DOI: 10.5001/omj.2015.80

Matched MeSH terms: Nasopharyngeal Neoplasms*

Cancer Survivorship in the Indo-Pacific: Priorities for Progress

Koczwara B, Chan A, Jefford M, Lam WWT, Taylor C, Wakefield CE, et al.

JCO Glob Oncol, 2023 Jan;9:e2200305.

PMID: 36749908 DOI: 10.1200/GO.22.00305

Matched MeSH terms: Neoplasms*

Two cases of pancreatic tumour

Hoops AL

Journal of the Malaya Branch of the British Medical Association, 1904.

Matched MeSH terms: Neoplasms; Pancreatic Neoplasms

Nasopharyngeal carcinoma. III. A pathological study of 170 cases

LAWLEY M

Med J Malaya, 1955 Dec;10(2):126-56.

PMID: 13308615

Matched MeSH terms: Nasopharyngeal Neoplasms*

Prediction of toxicity outcomes following radiotherapy using deep learning-based models: A systematic review

Tan D, Mohd Nasir NF, Abdul Manan H, Yahya N

Cancer Radiother, 2023 Sep;27(5):398-406.

PMID: 37482464 DOI: 10.1016/j.canrad.2023.05.001

PURPOSE: This study aims to perform a comprehensive systematic review of deep learning (DL) models in predicting RT-induced toxicity.

MATERIALS AND METHODS: A literature review was performed following the PRISMA guidelines. Systematic searches were performed in PubMed, Scopus, Cochrane and Embase databases from the earliest record up to September 2022. Related studies on deep learning models for radiotherapy toxicity prediction were selected based on predefined PICOS criteria.

RESULTS: Fourteen studies of radiotherapy-treated patients on different types of cancer [prostate (n=2), HNC (n=4), liver (n=2), lung (n=4), cervical (n=1), and oesophagus (n=1)] were eligible for inclusion in the systematic review. Information regarding patient characteristics and model development was summarized. Several approaches, such as ensemble learning, data augmentation, and transfer learning, that were utilized by selected studies were discussed.

CONCLUSION: Deep learning techniques are able to produce a consistent performance for toxicity prediction. Future research using large and diverse datasets and standardization of the study methodologies are required to improve the consistency of the research output.

Matched MeSH terms: Neoplasms*

Tumours of the upper respiratory and alimentary tracts. - (Continued). Acanthoma

Mekie EC

Journal of the Malaya Branch of the British Medical Association, 1938;2:316-28.

Matched MeSH terms: Neoplasms

Gynaecological malignancies

Adlan A

Family Practitioner, 1985;8:39-42.

Matched MeSH terms: Neoplasms

Fulltext Role of Pre-therapeutic (18)F-FDG PET/CT in Guiding the Treatment Strategy and Predicting Prognosis in Patients with Esophageal Carcinoma

Tan TH, Boey CY, Lee BN

Asia Ocean J Nucl Med Biol, 2016;4(2):59-65.

PMID: 27408893 DOI: 10.7508/aojnmb.2016.02.001

The present study aimed to evaluate the role of pre-therapeutic (18)fluorine-fluorodeoxyglucose positron emission tomography-computed tomography ((18)F-FDG PET-CT) and maximum standardized uptake value (SUVmax) in guiding the treatment strategy and predicting the prognosis of esophageal carcinoma, using the survival data of the patients.

Matched MeSH terms: Esophageal Neoplasms

Different time trend and management of esophagogastric junction adenocarcinoma in three Asian countries

Hatta W, Tong D, Lee YY, Ichihara S, Uedo N, Gotoda T

Dig Endosc, 2017 Apr;29 Suppl 2:18-25.

PMID: 28425657 DOI: 10.1111/den.12808

Esophagogastric junction (EGJ) adenocarcinoma has been on the increase in Western countries. However, in Asian countries, data on the incidence of EGJ adenocarcinoma are evidently lacking. In the present review, we focus on the current clinical situation of EGJ adenocarcinoma in three Asian countries: Japan, Hong Kong, and Malaysia. The incidence of EGJ adenocarcinoma has been reported to be gradually increasing in Malaysia and Japan, whereas it has stabilized in Hong Kong. However, the number of cases in these countries is comparatively low compared with Western countries. A reason for the reported difference in the incidence and time trend of EGJ adenocarcinoma among the three countries may be explained by two distinct etiologies: one arising from chronic gastritis similar to distal gastric cancer, and the other related to gastroesophageal reflux disease similar to esophageal adenocarcinoma including Barrett's adenocarcinoma. This review also shows that there are several concerns in clinical practice for EGJ adenocarcinoma. In Hong Kong and Malaysia, many EGJ adenocarcinomas have been detected at a stage not amenable to endoscopic resection. In Japan, histological curability criteria for endoscopic resection cases have not been established. We suggest that an international collaborative study using the same definition of EGJ adenocarcinoma may be helpful not only for clarifying the characteristics of these cancers but also for improving the clinical outcome of these patients.

Matched MeSH terms: Esophageal Neoplasms

Endoscopic gastric mucosal atrophy distinguishes the characteristics of superficial esophagogastric junction adenocarcinoma

Uedo N, Yoshio T, Yoshinaga S, Takeuchi M, Hatta W, Yano T, et al.

Dig Endosc, 2017 Apr;29 Suppl 2:26-36.

PMID: 28425653 DOI: 10.1111/den.12849

BACKGROUND AND AIM: Western studies have suggested two distinct etiologies of esophagogastric junction (EGJ) cancer: Helicobacter pylori-associated atrophic gastritis and non-atrophic gastric mucosa resembling esophageal adenocarcinoma. The present study investigated whether endoscopic gastric mucosal atrophy can distinguish between these two types of EGJ adenocarcinoma.

METHODS: Data were collected from patients with Siewert type II, T1 EGJ adenocarcinoma who underwent endoscopic or surgical resection at eight Japanese institutions in 2010-2015. Clinicopathological characteristics of EGJ cancers with and without endoscopic gastric mucosal atrophy were compared. EGJ was defined as the lower end of the palisade vein and/or the top of the gastric folds.

RESULTS: Of the 229 patients identified, 161 had endoscopic gastric mucosal atrophy and 68 did not. The latter group was younger (64 vs 70 years, P = 0.000); had a higher proportion of patients negative for H. pylori (90% vs 47%, P

Matched MeSH terms: Esophageal Neoplasms

Alloxan in the treatment of carcinoma of the liver

WILLIS GC, SIANG SC

Med J Malaya, 1960 Mar;14:166-76.

PMID: 13785569

Matched MeSH terms: Liver Neoplasms/therapy*; Neoplasms*

An overview of the management of primary malignant epithelial liver tumours in childhood

Hoe, Tuck Sang

Malaysian Journal of Child Health, 1994;6(1):9-11.

MyJurnal

Primary malignant epithelial liver tumours in childhood are rare tumours and used to be associated with poor survival. A review of the various current modalities of treatment is undertaken.

Matched MeSH terms: Liver Neoplasms

Salivary tumour

Monro JK

Med J Malaya, 1950;5.

Mixed salivary tumour is not confined to the parotid. It occurs also in the submandibular gland, and is the commonest cause of subepithelial tumour of the palate. It should be dissected out with its capsule through an adequate incision early, being insensitive to radiation. To shell it out of its capsule is to invite recurrence. It is a disease of young patients, onset at ages of 6 to 46 in this series, and grows slowly.

Matched MeSH terms: Salivary Gland Neoplasms

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