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  1. Fulltext Relationship between tear film stability, dry eye symptoms, and night driving vision among Malaysian adults
    Woi PJ, Pathmanathan P, Sieh SYH, Abd Rahman MH, Abdul Mutalib H, Bhandari M, et al.
    PLoS One, 2025;20(3):e0320223.
    PMID: 40138276 DOI: 10.1371/journal.pone.0320223
    Background Dry eye disease, a prevalent condition globally, affects the quality of the tear film and, subsequently, vision, especially during visually demanding tasks like driving at night. This study aims to evaluate the relationship between tear film stability, dry eye symptoms, and self-reported difficulties in night driving among Malaysian adults.

    METHODS: Ninety participants aged 18-40 years with at least one year of night driving experience were recruited. Tear film stability was assessed using non-invasive tear break-up time (NIBUT), while dry eye symptoms were measured with the Ocular Surface Disease Index (OSDI). Night driving vision difficulties were evaluated using the Vision and Night Driving Questionnaire (VND-Q).

    RESULTS: Participants with shorter NIBUT (mean =  3.95 ±  1.32 s; median =  3.97 s, IQR: 2.87-5.03 s) reported significantly greater difficulties in night driving compared to those with normal NIBUT (mean =  9.80 ±  3.86 s; median =  8.23 s, IQR: 6.90-11.70 s) (p night driving difficulties. Future studies should explore interventions aimed at improving tear film stability and dry eye symptoms to enhance driving safety at night.

    Matched MeSH terms: Night Vision/physiology
  2. A negative waveform in the scotopic response in a patient with phosphoglycerate kinase deficiency: a visual electrophysiology report
    Mohd Khialdin S, Grigg J, Rowe N, Crofts S, Wilson M, Troedson C
    Documenta ophthalmologica. Advances in ophthalmology, 2015 Dec;131(3):215-20.
    PMID: 26396085 DOI: 10.1007/s10633-015-9511-0
    Phosphoglycerate kinase (PGK) deficiency is an X-linked neurometabolic genetic disorder with variable systemic manifestations. So far, only one patient with retinal anomalies has been reported, but no visual electrophysiology findings were described. We report the first description of visual electrophysiology in a child with PGK deficiency. This provides further information for the site of involvement in the eye.
    Matched MeSH terms: Night Vision/physiology*
  3. Fulltext Retinitis punctata albescens presenting with tunnel vision: diagnostic dilemmas
    Norhayaty S., Nurul Dalila M.S., Tai, Evelyn L.M., Liza Sharmini A.T., Zunaina E., Azhany Y.
    Journal of Biomedical and Clinical Sciences, 2017;2(1):20-22.
    MyJurnal
    Tunnel vision is a classic sign among patients with advanced glaucoma. However, other conditions such as retinitis pigmentosa, optic neuritis and rod-cone dystrophy may be characterized by similar visual field defects. A 52-year-old lady with a family history of glaucoma presented with bilateral gradual loss of peripheral vision for two years. She claimed to have poor night vision about 20 years prior to this presentation. Her visual acuity was 6/7.5 in both eyes. The anterior chamber depth was moderate bilaterally, with Schaffer grading on gonioscopy of grade I to II. The intraocular pressure was 14 mmHg in both eyes. The optic discs appeared normal. Fundus examination showed scattered hypopigmented changes sparing the fovea. Humphrey visual field test revealed bilateral constricted visual fields. She was diagnosed with retinitis punctata albescens (RPA) based on her symptom of poor night vision, supported by the diffuse hypopigmented changes in her fundi. The management of this condition involves careful counselling regarding the genetic nature of the disease and its progressive course. We discuss this case to illustrate the importance of a thorough history taking and careful fundus examination in the workup of patients presenting with tunnel vision.
    Matched MeSH terms: Night Vision
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