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  1. Dessie BK, Mehari B, Osman M, Gari SR, Desta AF, Melaku S, et al.
    Biometals, 2022 Dec;35(6):1341-1358.
    PMID: 36163536 DOI: 10.1007/s10534-022-00448-8
    The Akaki River in the Upper Awash Basin, which flows through Addis Ababa, the capital city of Ethiopia, has been highly polluted by sewage from factories and residential areas. A population-based cross-sectional study was used to assess the association between trace elements and kidney injury from residents living in polluted areas downstream (Akaki-Kality) versus upstream (Gullele) in Sub-Cities of Addis Ababa. A total of 95 individuals (53 from Akaki-Kality and 42 from Gullele) were included in the study. Kidney injury molecule 1 (KIM-1), lead, arsenic, cadmium, cobalt, lead, manganese, zinc, iron, copper, chromium and nickel were evaluated in residents' urine and nail samples. A large proportion (74%) of the sample population contained KIM-1, including 81% residents in Akaki-Kality and 64% residents in Gullele. KIM-1 was, however, not significantly different (p = 0.05) between the two Sub-Cities, with median of 0.224 ng/mL in Akaki-Kality and 0.152 ng/mL in Gullele. Most of the analyzed elements, except Pb, As, Cd and Co, were found in all of the nail samples, with median (µg/g) in the range of 442‒714 Fe, 97.0‒246 Zn, 11.6‒24.1 Mn, 4.49‒5.85 Cu, 1.46‒1.66 Cr and 1.22‒1.41 Ni. The high incidence of KIM-1 indicates a potential for long term renal tubular damage among residents of the Sub-Cities. The concentrations of the elements in nails were, however, not significantly associated (p = 0.05) with the corresponding levels of KIM-1 in urine. Hence, the observed KIM-1 might be related to exposure to toxic substances or factors other than those included in this study.
    Matched MeSH terms: Ethiopia/epidemiology
  2. Ali AS, Gari SR, Goodson ML, Walsh CL, Dessie BK, Ambelu A
    PLoS One, 2023;18(11):e0288425.
    PMID: 37939075 DOI: 10.1371/journal.pone.0288425
    INTRODUCTION: Childhood diarrhea is one of the major contributors to the morbidity of under-five children in Ethiopia. Although researchers determine the risk factors varyingly, the exposure route to the pathogens is usually complicated. This study aims to investigate the prevalence and risk factors of diarrhea among children under the age of five among wastewater irrigation farming households in Addis Ababa, Ethiopia.

    METHODS: Cross-sectional study was conducted among 402 farming households from November 2021 to February 2022. Data was collected using a face-to-face interviewer-administered questionnaire. Stata version 14 software was used to analyze data. Factors associated with the prevalence of diarrhea was identified using binary logistic regression. Multivariable analysis was carried out to determine an adjusted odds ratio at a confidence level of 95% and level of significance at 0.05.

    RESULTS: The overall prevalence of under-five children diarrheal cases was 22.3%. The odds of diarrhea are associated with a multitude of variables. Major wastewater-related determinants associated with diarrhea are body washing with irrigation water [AOR: 37.7, 95%CI (3.1, 358)], contaminated cloth with irrigation water [AOR:10.8,95%CI(0.6, 205)], use of protective clothing during farm work [28.9,95%CI (3.9, 215)], use of farm work cloths at home [AOR: 31.7, 95%CI (4.4, 226)], and bringing unwashed farm tools to home [94 (5.7, 1575)].

    CONCLUSION: The high prevalence of under-five children diarrheal disease among wastewater irrigation households was strongly associated with factors related to occupational exposure. Thus, to decrease childhood diarrheal among urban agriculture farmers, appropriate precautions need to be taken.

    Matched MeSH terms: Ethiopia/epidemiology
  3. Ali AS, Gari SR, Goodson ML, Walsh CL, Dessie BK, Ambelu A
    Int J Environ Health Res, 2025 Apr;35(4):909-921.
    PMID: 38944842 DOI: 10.1080/09603123.2024.2374001
    The importance of diarrhea risk associated with wastewater exposure in agriculture is almost unknown. This study aimed to examine diarrheal infection and risk factors among farmers using wastewater for irrigation in Addis Ababa. A cross-sectional study was employed among 380 farmers (190 exposed and 190 unexposed farmers). Among these, a cohort of 200 adults (100 wastewater-exposed, 100 unexposed farmers) aged 25-69 years were selected and followed up biweekly for two successive vegetables growing seasons to examine the incidence of diarrhea. The incidence rate of reported diarrhea was 12 episodes per 1,000 person-weeks at risk and a maximum of 17 episodes per 1,000 person-weeks at risk. Strongly associated risk factors include washing body and clothes with wastewater [AOR: 4.2, 95%CI (1, 11.2)], using working clothes at home [AOR: 4.7, 95%CI (0.25, 87)], and wearing protective cloth [AOR: 5.6, 95 CI (0.3, 70)]. Moreover, hand washing after work, washing feet and boots, and on-site hand washing were significant determinants of farmers' diarrhea. Exposure to wastewater significantly contributes to the risk of diarrhea among adults. Significant determinants of diarrhea among farmers include washing the body and clothes with irrigation water, contamination with soil and irrigation water, and on-site hand washing. Increased risk factors include hand contamination, washing vegetables with irrigation water, eating raw vegetables, and using work clothes at home.
    Matched MeSH terms: Ethiopia/epidemiology
  4. Gebrezihier BG, Abdulkadir M, Sbhatu DB, Tsegay E, Berhe GG
    BMC Res Notes, 2024 Nov 12;17(1):336.
    PMID: 39533436 DOI: 10.1186/s13104-024-06998-z
    OBJECTIVE: Dandruff, a condition caused by lipophilic Malassezia fungi, is an excessive shed of dead skin cells from the scalp. Effective preventive and curative measures of the condition depend on knowledge and understanding of the prevalence of the condition, the common etiologic species, and the associated factors. This study aimed to investigate the prevalence, common etiologic species, and associated factors of Malassezia infection in Mekelle City, Ethiopia.

    METHOD: A facility-based cross-sectional study was conducted from February 2019 to June 2020 involving 217 participants who were visiting dermatology clinics to seek treatment for dandruff conditions. Information on the socio-demographic characteristics and hair care behaviors of the participants was obtained. Isolation and identification of Malassezia species from scalp scrapings using cultural and biochemical tests were carried out.

    RESULTS: Out of the 217 participants with dandruff, 111 (51.15%) were positive for Malassezia fungi. One hundred forty (140) Malassezia isolates were collected from the 111 positive participants. Further study of the isolates yielded three etiologic species: Malassezia globosa (67.15%), M. furfur (21.70%), and M. restricta (12.15%). Demographic characteristics, namely gender (AOR = 2.605; 95%CI: 1.427 - 4.757) and age (AOR = 2.667; 95%CI: 1.046 - 6.795), as well as hair care behaviors, namely use of hair oil (AOR = 2.964; 95%CI: 1.288 - 6.820), were associated with the presence of Malassezia species. However, the use of anti-dandruff shampoo (AOR = 2.782; 95%CI: 1.301 - 10.993) was negatively associated with the presence of Malassezia species among the participants with dandruff conditions. These findings open opportunities to devise effective prevention, management, and control measures for Malassezia-based dandruff conditions.

    Matched MeSH terms: Ethiopia/epidemiology
  5. Sheferaw WE, Ogunmola GA, Marzo RR, Abebaw S, Belay A, James BC, et al.
    BMC Pediatr, 2025 Jan 16;25(1):35.
    PMID: 39819552 DOI: 10.1186/s12887-025-05400-6
    BACKGROUND: Despite numerous government nutrition-specific and sensitive interventions, undernutrition (e.g., underweight) remains the major public health concern among under-five-year-old children in Ethiopia. Therefore, this study aimed to assess underweight and associated factors among children in Ethiopia using 2016 EDHS data.

    METHOD: The current study used 9,013 children under five years old. An ordinal logistic regression (e.g., proportional odds model) was applied to determine the associated risk factors of being underweight. The current study used SAS software version 9.4 at the 5% significance level.

    RESULTS: The prevalence of underweight was 25.3%. Variables such as children's sex, place of residence, whether the child is twin at birth, breastfeeding status, size of children at birth, childbirth order, employment status of mothers, parents' educational level, children's age groups, the incidence of diarrhea in the past two weeks, and baby fortified food were statistically associated with underweight among under-five age in years.

    CONCLUSIONS: Underweight among under-five children is predicted by place of residence. In addition, there is a regional disparity of underweight among children. Therefore, further effort is needed to improve health education in children's welfare and health facilities to enhance patients' understanding of proper information and feeding.

    Matched MeSH terms: Ethiopia/epidemiology
  6. Cherenet T, Sani RA, Panandam JM, Nadzr S, Speybroeck N, van den Bossche P
    Onderstepoort J Vet Res, 2004 Dec;71(4):307-12.
    PMID: 15732457
    During a period of four consecutive years, trypanosomosis surveys were conducted in a tsetse-infested and tsetse-free area of the Amhara Region of north-west Ethiopia. In each study area randomly selected communal cattle were sampled and their blood was investigated using parasitological diagnostic methods. At the same time the population of biting flies was sampled. The monthly average prevalence of trypanosome infections in cattle did not differ significantly between study areas. In both study areas, the prevalence of trypanosome infections was highest during the long rainy season. Trypanosome infections were mainly due to Trypanosoma vivax and they significantly reduced the average packed cell volume and the body condition of the animals. The monthly prevalence of infection was correlated with the density of biting flies, such as Tabanidae and Stomoxys spp., in the preceding month suggesting an important role of mechanical transmission in the epidemiology of trypanosomosis in both areas.
    Matched MeSH terms: Ethiopia/epidemiology
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