MyMedR

Fulltext Palatal pleomorphic adenoma and its management with island flaps

Janakarajah N, Dias AP

Med J Malaysia, 1983 Sep;38(3):251-4.

PMID: 6323936

Matched MeSH terms: Palatal Neoplasms/surgery*

Atypical peripheral ameloblastoma of the palate

Siar CH, Ng KH, Ngui CH, Chuah CH

J Laryngol Otol, 1990 Mar;104(3):252-4.

PMID: 2341785

Clinical, radiological and histological characteristics of the peripheral ameloblastoma are briefly outlined. A case found occurring in the palate and presenting with atypical histological features is reported. The differential diagnosis of this lesion, its treatment and histogenesis are discussed.

Matched MeSH terms: Palatal Neoplasms/pathology*

Fulltext Haemangioma of the uvula causing loud habitual snoring--a rare entity

Thong JF, Pang KP, Siow JK

Med J Malaysia, 2008 Dec;63(5):408-9.

PMID: 19803302

Mucosal haemangiomas are unusual and typically involve frequently traumatised areas such as the lip, buccal mucosa and lateral borders of the tongue. Uvular haemangioma is rare and to our knowledge, has never been reported to cause obstructive sleep apnoea (OSA). We report an unusual case of uvular haemangioma causing loud habitual snoring and symptoms suggestive of OSA. This case report illustrates a rare cause of OSA and demonstrates the efficacy of surgery for obvious obstructive lesions of the pharynx.

Matched MeSH terms: Palatal Neoplasms/complications*; Palatal Neoplasms/pathology; Palatal Neoplasms/surgery

Carcinosarcoma of the palate: report of a case with a diagnosis of sarcomatoid metastasis by fine needle aspiration cytology

Jayaram G, Elsayed EM

Acta Cytol., 2005 Sep-Oct;49(5):520-4.

PMID: 16334029

BACKGROUND: Carcinosarcoma (sarcomatoid carcinoma) is a rare tumor with a high predilection for the aerodigestive tract. Cytologic diagnosis of metastatic carcinosarcoma has been reported in very few cases.

CASE: An 84-year-old woman presented with a 2-cm-diameter, right cervical lymph node that was referred for fine needle aspiration cytology (FNAC). She had received radiotherapy for a palatal squamous cell carcinoma 2 years earlier. The FNAC smears had a sarcomatoid appearance. Repeat fine needle aspiration was performed, with cytologic and immunocytochemical staining. Careful consideration of the cytologic and immunophenotypic features led to an impression of carcinosarcoma. Histologic sections of the palatal biopsy that had been previously diagnosed as squamous cell carcinoma were reviewed, and a final diagnosis of carcinosarcoma was established.

CONCLUSION: Metastasis of rare lesions, such as carcinosarcoma may be confusing and difficult to diagnose on FNAC, especially when the cytologic sample shows a predominantly sarcomatoid component. The difficulty is compounded when the sarcomatoid component happens to have been overlooked on the initial histologic assessment. With representative cytologic sampling, immunocytochemical staining and review of the histologic material, the correct diagnosis was achieved in this case.

Matched MeSH terms: Palatal Neoplasms/diagnosis*; Palatal Neoplasms/pathology; Palatal Neoplasms/secondary*

An immunohistochemical study of two cases of either peripheral odontogenic fibroma (WHO type) or peripheral ameloblastoma

Chong Huat Siar, Kok Han Ng

J Nihon Univ Sch Dent, 1996 Mar;38(1):52-6.

PMID: 8648412

Two cases of either peripheral odontogenic fibroma (POF) (WHO type) or peripheral ameloblastoma are reported. Their immunohistochemical characteristics were investigated in an attempt to clarify their histogenesis. The results showed that the epithelial component of this neoplasm tended to retain its distinct odontogenic character and expressed a keratin profile different from that of the overlying oral epithelium from which both cases most probably originated. The connective tissue element of these tumors was vimentin-positive and S-100 protein negative, confirming their mesodermal nature but precluding the possibility of ectomesenchymal derivation. No reactivity for desmin was noted.

Matched MeSH terms: Palatal Neoplasms/pathology; Palatal Neoplasms/chemistry

Oral carcinoma in the Chinese female

Ramanathan K, Lakshimi S

Med J Malaysia, 1973 Dec;28(2):84-7.

PMID: 4276246

Matched MeSH terms: Palatal Neoplasms/epidemiology

Rehabilitation of an extraoral and intraoral defect complicated with microstomia. A study case

Abdulhadi LM

Eur J Prosthodont Restor Dent, 2012 Jun;20(2):81-5.

PMID: 22852525

A 72-year-old man was referred from the surgery department for rehabilitation following surgical resection of Basaloid carcinoma. The first surgical intervention involved the anterior palatal region and was restored with a simple obturator. Two years later further surgery was undertaken to excise a recurrent tumor in the nose and part of the cheek. This resulted in an exposed nasal cavity and maxillary sinus. In addition, there was a small oral aperture composed of thin tissue that stretched to its maximum due to scar formation. The defect was restored with a full thickness skin flap but it subsequently broke down leaving the midface exposed with limited mouth opening due to tissue contraction and scar formation after the flap operation. The defect was rehabilitated with Co-Cr obturator intraorally and a silicone nose retained to the naso-palatal extension of the obturator by a magnet extraorally. This resulted in practically good retention, placement, and adaptation of the two parts of the prosthesis.

Matched MeSH terms: Palatal Neoplasms/complications; Palatal Neoplasms/rehabilitation

Oral carcinoma in the first three decades of life

Ramanathan K

Med J Malaya, 1972 Sep;27(1):20-6.

PMID: 4345644

Matched MeSH terms: Palatal Neoplasms/epidemiology; Palatal Neoplasms/pathology

Oral carcinoma in the Malay male

Ramanathan K, Lakshimi S

Med J Malaysia, 1974 Mar;28(3):143-8.

PMID: 4278210

Matched MeSH terms: Palatal Neoplasms/epidemiology

Frequency of oral precancerous conditions in 407 Malaysians--with correlation to oral habits

Ramanathan K, Canaganayagam A, Keat TC, Retnanesan A

Med J Malaysia, 1973 Mar;27(3):173-81.

PMID: 4268919

Matched MeSH terms: Palatal Neoplasms/epidemiology

Epstein-Barr virus (EBV) in Malaysian upper-aerodigestive-tract lymphoma: incidence and sub-type

Peh SC, Sandvej K, Pallesen G

Int J Cancer, 1995 May 4;61(3):327-32.

PMID: 7729943

Epstein-Barr virus (EBV) type B, a less potent transformer of B lymphocytes than type A, has rarely been detected in EBV-associated neoplasms except in AIDS-related lymphomas, in which about 50% of the cases contained this sub-type. In this study we analyzed the association of EBV and the distribution of virus sub-types in Asian non-Hodgkin's lymphoma (NHL) of the upper aerodigestive tract. We studied archival material of 29 NHL cases from Malaysia. B- and T-cell associated antigens were demonstrated by immunohistochemistry, and EBV early RNA EBER-1 was demonstrated using the RNA in situ hybridization technique. EBV was detected in the majority of tumour cells in 11/13 T-NHL but in only 1/16 B-NHL. EBV was sub-typed by single-step polymerase chain reaction of the EBNA-2 gene. This was successful in 9/10 cases of EBER-1-positive tumours and all contained type-A virus only. Our results showed a preponderance of T-cell lymphoma of the upper aerodigestive tract in the ethnic Chinese group of Malaysian patients, and EBV was strongly associated with T-NHL but not with B-NHL. Our results suggest that type-A EBV is the prevalent sub-type in Asian NHL of the upper aerodigestive tract, similarly to findings in Asian nasopharyngeal carcinoma.

Matched MeSH terms: Palatal Neoplasms/immunology; Palatal Neoplasms/epidemiology; Palatal Neoplasms/pathology; Palatal Neoplasms/virology*

Prevalence and incidence of oral cancer in low- and middle-income countries: A scoping review

Shrestha AD, Vedsted P, Kallestrup P, Neupane D

Eur J Cancer Care (Engl), 2020 Mar;29(2):e13207.

PMID: 31820851 DOI: 10.1111/ecc.13207

INTRODUCTION: Oral cancer is common cancer in many low- and middle-income countries (LMICs) with a low five-year survival rate. It is among the four most common types of cancer in South East Asia region. In South-Central Asia, lip and oral cavity cancer is the second most common cancer according to the specific cancer types.

METHODS: This scoping review intended to investigate published studies on the current prevalence and incidence of oral cancer in LMICs. The review was conducted applying the search words "Oral Cancer" and "Mouth neoplasm" as the Medical Subject Heading (MeSH) major topic and "Epidemiology" and ("prevalence" OR "incidence") as the MeSH subheading; the search was supplemented by cross-references. Included studies met the following criteria: original studies, reporting of prevalence or incidence rates, population-based studies, studies in English language and studies involving humans.

RESULTS: The sample sizes ranged from 486 to 101,761 with 213,572 persons included. Buccal mucosa is one of the most common sites of oral cancer, associated with the widespread exposure to chewing tobacco. The incidence is likely to rise in the region where gutkha, pan masala, pan-tobacco and various other forms of chewing tobacco are popular.

CONCLUSION: This review contributes to useful information on prevalence and incidence estimates of oral cancer in LMICs.

Matched MeSH terms: Palatal Neoplasms/epidemiology

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